Search Results - "Hill, Colin S"

A safety study of intraoperative radiation therapy following stereotactic body radiation therapy and multi-agent chemotherapy in the treatment of localized pancreatic adenocarcinoma: study protocol of a phase I trial by Reddy, Abhinav V, Hill, Colin S, Zheng, Lei, He, Jin, Narang, Amol K

“…Localized pancreatic adenocarcinoma carries a poor prognosis even after aggressive therapy. Up to 40% of patients may develop locoregional disease as the first…”
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Vertebral body and splenic irradiation are associated with lymphopenia in localized pancreatic cancer treated with stereotactic body radiation therapy by Reddy, Abhinav V, Deek, Matthew P, Jackson, Juan F, Hill, Colin S, Sehgal, Shuchi, He, Jin, Zheng, Lei, Herman, Joseph M, Meyer, Jeffrey, Narang, Amol K

“…The purpose of this study was to determine if vertebral body and splenic dosimetry was associated with the development of lymphopenia in patients with…”
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Fiducial-based image-guided SBRT for pancreatic adenocarcinoma: Does inter-and intra-fraction treatment variation warrant adaptive therapy? by Hill, Colin S, Han-Oh, Sarah, Cheng, Zhi, Wang, Ken Kang-Hsin, Meyer, Jeffrey J, Herman, Joseph M, Narang, Amol K

“…Variation in target positioning represents a challenge to set-up reproducibility and reliability of dose delivery with stereotactic body radiation therapy…”
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Upfront Chemotherapy Followed by Stereotactic Body Radiation Therapy with or without Surgery in Older Patients with Localized Pancreatic Cancer: A Single Institution Experience and Review of the Literature by Reddy, Abhinav V, Sehgal, Shuchi, Hill, Colin S, Zheng, Lei, He, Jin, Herman, Joseph M, Meyer, Jeffrey, Narang, Amol K

“…To report on clinical outcomes and toxicity in older (age ≥ 70 years) patients with localized pancreatic cancer treated with upfront chemotherapy followed by…”
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Impact of somatic mutations on clinical and pathologic outcomes in borderline resectable and locally advanced pancreatic cancer treated with neoadjuvant chemotherapy and stereotactic body radiotherapy followed by surgical resection by Reddy, Abhinav V, Hill, Colin S, Sehgal, Shuchi, Ding, Ding, Hacker-Prietz, Amy, He, Jin, Zheng, Lei, Herman, Joseph M, Meyer, Jeffrey, Narang, Amol K

“…The purpose of this study was to determine if somatic mutations are associated with clinical and pathologic outcomes in patients with borderline resectable…”
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Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ) by Rahman, Ghazi M, Shanker, Sreejesh, Lewin, Nancy E, Kedei, Noemi, Hill, Colin S, Prasad, B V Venkataram, Blumberg, Peter M, Das, Joydip

“…PKC (protein kinase C) θ is predominantly expressed in T-cells and is critically involved in immunity. Design of PKCθ-selective molecules to manage autoimmune…”
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Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP by Garcia, Lia C., Donadío, Lucia Gandolfi, Mann, Ella, Kolusheva, Sofiya, Kedei, Noemi, Lewin, Nancy E., Hill, Colin S., Kelsey, Jessica S., Yang, Jing, Esch, Timothy E., Santos, Marina, Peach, Megan L., Kelley, James A., Blumberg, Peter M., Jelinek, Raz, Marquez, Victor E., Comin, Maria J.

“…[Display omitted] The development of selective agents capable of discriminating between protein kinase C (PKC) isoforms and other diacylglycerol…”
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The Current Role of Radiation in Pancreatic Cancer and Future Directions by Hill, Colin S., Herman, Joseph M.

“…Survival outcomes for localized pancreatic adenocarcinoma remains poor. Multimodality therapeutic regimens are critical to maximizing survival outcomes for…”
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Phase I Study of Adjuvant Allogeneic GM-CSF-Transduced Pancreatic Tumor Cell Vaccine, Low Dose Cyclophosphamide, and SBRT followed by FFX in High-Risk Resected Pancreatic Ductal Adenocarcinoma by Hill, Colin S., Parkinson, Rose, Jaffee, Elizabeth M., Sugar, Elizabeth, Zheng, Lei, Onners, Beth, Weiss, Matthew J., Wolfgang, Christopher L., Cameron, John L., Pawlik, Timothy M., Rosati, Lauren, Le, Dung T., Hacker-Prietz, Amy, Lutz, Eric R., Schulick, Richard, Narang, Amol K., Laheru, Daniel A., Herman, Joseph M.

“…Local and distant progression remain common following resection of resectable pancreatic ductal adenocarcinoma (PDAC) despite adjuvant multiagent chemotherapy…”
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Neoadjuvant Stereotactic Body Radiotherapy After Upfront Chemotherapy Improves Pathologic Outcomes Compared With Chemotherapy Alone for Patients With Borderline Resectable or Locally Advanced Pancreatic Adenocarcinoma Without Increasing Perioperative Toxicity by Hill, Colin S., Rosati, Lauren M., Hu, Chen, Fu, Wei, Sehgal, Shuchi, Hacker-Prietz, Amy, Wolfgang, Christopher L., Weiss, Matthew J., Burkhart, Richard A., Hruban, Ralph H., De Jesus-Acosta, Ana, Le, Dung T., Zheng, Lei, Laheru, Daniel A., He, Jin, Narang, Amol K., Herman, Joseph M.

“…Background Patients with borderline resectable pancreatic cancer (BRPC) or locally advanced pancreatic cancer (LAPC) are at high risk of margin-positive…”
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Effectiveness of the nutrition referral system in a multidisciplinary pancreatic cancer clinic by Wong, Sydnee C., Reddy, Abhinav V., Hacker-Prietz, Amy, Kress, Laura, Pathak, Priya, Hill, Colin S., Lin, Timothy A., Herman, Joseph M., He, Jin, Zheng, Lei, Brown, Mary-Eve, Narang, Amol K.

“…Purpose Proactive nutrition screening and intervention is associated with improved outcomes for patients with pancreatic adenocarcinoma (PDAC). To better…”
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High neutrophil-to-lymphocyte ratio following stereotactic body radiation therapy is associated with poor clinical outcomes in patients with borderline resectable and locally advanced pancreatic cancer by Reddy, Abhinav V, Hill, Colin S, Sehgal, Shuchi, He, Jin, Zheng, Lei, Herman, Joseph M, Meyer, Jeffrey, Narang, Amol K

“…The purpose of this study is to report on the prognostic role of pre- and post-stereotactic body radiation therapy (SBRT) neutrophil-to-lymphocyte ratio (NLR)…”
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Multiagent Chemotherapy and Stereotactic Body Radiation Therapy in Patients with Unresectable Pancreatic Adenocarcinoma: A Prospective Nonrandomized Controlled Trial by Hill, Colin S., Rosati, Lauren, Wang, Hao, Tsai, Hua-Ling, He, Jin, Hacker-Prietz, Amy, Laheru, Daniel A., Zheng, Lei, Sehgal, Shuchi, Bernard, Vincent, Le, Dung T., Pawlik, Timothy M., Weiss, Matthew J., Narang, Amol K., Herman, Joseph M.

“…In a prospective multicenter study, gemcitabine monotherapy followed by stereotactic body radiation therapy (SBRT) was well tolerated with outcomes comparable…”
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Location, Location, Location: What Should be Targeted Beyond Gross Disease for Localized Pancreatic Ductal Adenocarcinoma? Proposal of a Standardized Clinical Tumor Volume for Pancreatic Ductal Adenocarcinoma of the Head: The “Triangle Volume” by Hill, Colin S., Fu, Wei, Hu, Chen, Sehgal, Shuchi, Reddy, Abhinav V., He, Jin, Herman, Joseph M., Meyer, Jeffrey J., Zaheer, Atif, Narang, Amol K.

“…In patients with borderline resectable or locally advanced pancreatic adenocarcinoma (BRPC/LAPC), local failure rates after resection remain significant, even…”
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Stereotactic body radiation therapy for the treatment of locally recurrent pancreatic cancer after surgical resection by Reddy, Abhinav V, Hill, Colin S, Sehgal, Shuchi, He, Jin, Zheng, Lei, Herman, Joseph M, Meyer, Jeffrey, Narang, Amol K

“…To report on a cohort of radiation-naïve patients with pancreatic cancer who developed isolated local recurrence following surgical resection and were…”
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Post-radiation neutrophil-to-lymphocyte ratio is a prognostic marker in patients with localized pancreatic adenocarcinoma treated with anti-PD-1 antibody and stereotactic body radiation therapy by Reddy, Abhinav V, Hill, Colin S, Sehgal, Shuchi, Zheng, Lei, He, Jin, Laheru, Daniel A, Jesus-Acosta, Ana De, Herman, Joseph M, Meyer, Jeffrey, Narang, Amol K

“…To investigate the role of pre- and post-stereotactic body radiation therapy (SBRT) neutrophil-to-lymphocyte ratio (NLR) in patients with localized pancreatic…”
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Design and synthesis of protein kinase C epsilon selective diacylglycerol lactones (DAG-lactones) by Ann, Jihyae, Yoon, Suyoung, Baek, Jisoo, Kim, Da Hye, Lewin, Nancy E., Hill, Colin S., Blumberg, Peter M., Lee, Jeewoo

“…DAG-lactones afford a synthetically accessible, high affinity platform for probing structure activity relationships at the C1 regulatory domain of protein…”
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Charge Density Influences C1 Domain Ligand Affinity and Membrane Interactions by Kelsey, Jessica S., Geczy, Tamas, Lewin, Nancy E., Kedei, Noemi, Hill, Colin S., Selezneva, Julia S., Valle, Christopher J., Woo, Wonhee, Gorshkova, Inna, Blumberg, Peter M.

“…The C1 domain, which represents the recognition motif on protein kinase C for the lipophilic second messenger diacylglycerol and its ultrapotent analogues, the…”
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Creating Inclusive and Accessible Residency Training programs: Lessons Learned from Establishing a Deaf and American Sign Language Inclusive Model for Residency Training by Hill, Colin S., Deville, Curtiland, Kiess, Ana, Narang, Amol K., Ratnanather, Tilak, Bienstock, Jessica, Brinckerhoff, Loring, Hodukavich, Aaron, Anderson, Roberta, Alcorn, Sara, DeWeese, Theodore, Viswanathan, Akila, Page, Brandi. R.

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