Search Results - "Hill, Aubrey R"

Synthesis of long prebiotic oligomers on mineral surfaces by Ferris, James P, Hill, Aubrey R, Liu, Rihe, Orgel, Leslie E

“…Most theories of the origin of biological organization assume that polymers with lengths in the range of 30-60 monomers are needed to make a genetic system…”
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Photooxidation of oligodeoxynucleotides by uranyl ions by Hill, Aubrey R, Orgel, Leslie E

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Polymerization on the rocks: negatively-charged alpha-amino acids by Hill, A. R. Jr, Bohler, C., Orgel, L. E., Bada, J. L.

“…Oligomers of the negatively-charged amino acids, glutamic acid, aspartic acid, and O-phospho-L-serine are adsorbed by hydroxylapatite and illite with…”
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Template-directed oligomerization of 3-isoadenosine 5'-phosphate by Hill, Aubrey R., Jr, Orgel, Leslie E., Kumar, Shiv, Leonard, Nelson J.

“…Template-directed oligomerization of an activated derivative of 3-isoadenosine 5'-phosphate (piA) on polyuridylic acid was studied. The reaction of ImpiA is…”
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Catalysis of the oligomerization of O-phospho-serine, aspartic acid, or glutamic acid by cationic micelles by Bohler, C, Hill, Jr, A R, Orgel, L E

“…Treatment of relatively concentrated aqueous solutions of O-phospho-serine (50 mM), aspartic acid (100 mM) or glutamic acid (100 mM) with carbonyldiimidazole…”
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Oligomerization of L-gamma-carboxyglutamic acid by Hill, A. R. Jr, Orgel, L. E., Bada, J. L.

“…Unlike glutamic acid, L-gamma-carboxyglutamic acid does not oligomerize efficiently when treated with carbonyldiimidazole in aqueous solution. However,…”
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Which 3-ribofuranosyl-substituted purine 5'-phosphates undergo template-directed oligomerization ? by HILL, A. R, SHIV KUMAR, PATIL, V. D, LEONARD, N. J, ORGEL, L. E

“…We have studied the oligomerization reactions of the 2-methylimidazolide derivatives of 3-isoisoguanosine 5'-phosphate (2) and 3-isoxanthosine 5'-phosphate (5)…”
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Cyclization of nucleotide analogues as an obstacle to polymerization by Hill, A. R. Jr, Nord, L. D., Orgel, L. E., Robins, R. K.

“…Cyclization of activated nucleotide analogues by intramolecular phosphodiester-bond formation is likely to compete very effectively with template-directed…”
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Oligomerization of negatively-charged amino acids by carbonyldiimidazole by Hill, Jr, A R, Orgel, L E

“…The carbonyldiimidazole-induced oligomerizations of aspartic acid, glutamic acid and O-phospho-serine are amongst the most efficient reported syntheses of…”
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The limits of template-directed synthesis with nucleoside-5'-phosphoro(2-methyl)imidazolides by Hill, Aubrey R., Orgel, Leslie E., Wu, Taifeng

“…In earler work we have shown that C-rich templates containing isolated A, T or G residues and short oligo(G) sequences can be copied effectively using…”
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