Search Results - "Hilger, C S"

Paramagnetic metalloporphyrins: infarct avid contrast agents for diagnosis of acute myocardial infarction by MRI by Marchal, G, Ni, Y, Herijgers, P, Flameng, W, Petré, C, Bosmans, H, Yu, J, Ebert, W, Hilger, C S, Pfefferer, D, Semmler, W, Baert, A L

“…In previous experiments in tumors we demonstrated that metalloporphyrins are particularly avid for nonviable tumor components. This study was performed to find…”
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Synthesis of 1-(2-Aminophenyl)isoquinolines and the Biological Activity of Their cis-Dichloro Platinum(II) Complexes by von Nussbaum, Franz, Miller, Bernhard, Wild, Stefan, Hilger, Christoph S, Schumann, Susanne, Zorbas, Haralabos, Beck, Wolfgang, Steglich, Wolfgang

“…The broad biological effects of isoquinolines prompted us to use them as chelating, nonleaving ligands in cis-platinum(II) antitumor complexes. The synthesis…”
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Molecular Imaging of Atherosclerosis Using a Technetium-99m-Labeled Endothelin Derivative by Dinkelborg, Ludger M, Duda, Stephan H, Hanke, Hartmut, Tepe, Gunnar, Hilger, Christoph S, Semmler, Wolfhard

“…Endothelins have been implicated in the pathogenesis of atherosclerosis and restenosis. The aim of this study was to characterize the potential of an…”
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Paramagnetic metalloporphyrins: from enhancers of malignant tumors to markers of myocardial infarcts by Ni, Y, Marchal, G, Herijgers, P, Flameng, W, Petré, C, Ebert, W, Hilger, C S, Pfefferer, D, Semmler, W, Baert, A L

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18F-labelling of a potent nonpeptide CCR1 antagonist: synthesis of 1-(5-chloro-2-{2-[(2R)-4-(4-[18F]fluorobenzyl)-2-methylpiperazin-1-yl]-2-oxoethoxy}phenyl)urea in an automated module by Mäding, P., Füchtner, F., Johannsen, B., Steinbach, J., Hilger, C. S., Friebe, M., Halks-Miller, M., Horuk, R., Mohan, R.

“…The synthesis of 1‐(5‐chloro‐2‐{2‐[(2R)‐4‐(4‐[18F]fluorobenzyl)‐2‐methylpiperazin‐1‐yl]‐2‐oxoethoxy}phenyl)urea ([18F]4), a potent nonpeptide CCR1 antagonist,…”
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Tc-99m-labeled endothelin derivative for imaging of experimentally induced atherosclerosis by Tepe, Gunnar, Duda, Stephan H., Meding, Jörg, Brehme, Ute, Ritter, Josef, Hanke, Hartmut, Hilger, Christoph S., Claussen, Claus D., Dinkelborg, Ludger M.

“…Objective: to characterize the potential of an endothelin derivative labeled with technetium-99m (Tc-99m) for the imaging of experimentally induced…”
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Localization of metalloporphyrin-induced "specific" enhancement in experimental liver tumors: comparison of magnetic resonance imaging, microangiographic, and histologic findings by Ni, Y, Marchal, G, Yu, J, Lukito, G, Petré, C, Wevers, M, Baert, A L, Ebert, W, Hilger, C S, Maier, F K

“…We investigated the tumor specificity of gadolinium mesoporphyrin (Gd-MP) and manganese tetraphenylporphyrin (Mn-TPP) as magnetic resonance (MR) imaging…”
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Tumor Targeting by an Aptamer by Hicke, Brian J, Stephens, Andrew W, Gould, Ty, Chang, Ying-Fon, Lynott, Cynthia K, Heil, James, Borkowski, Sandra, Hilger, Christoph-Stephan, Cook, Gary, Warren, Stephen, Schmidt, Paul G

“…Aptamers are small oligonucleotides that are selected to bind tightly and specifically to a target molecule. We sought to determine whether aptamers have…”
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Radioimmunotherapy of Solid Tumors by Targeting Extra Domain B Fibronectin: Identification of the Best-Suited Radioimmunoconjugate by BERNDORFF, Dietmar, BORKOWSKI, Sandra, SIEGER, Stephanie, ROTHER, Axel, FRIEBE, Matthias, VITI, Francesca, HILGER, Christoph S, CYR, John E, DINKELBORG, Ludger M

“…Purpose: The expression of extra domain B (ED-B) fibronectin is always associated with angiogenic processes and can be exclusively observed in tissues…”
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18 F‐labelling of a potent nonpeptide CCR1 antagonist: synthesis of 1‐(5‐chloro‐2‐{2‐[(2R)‐4‐(4‐[ 18 F]fluorobenzyl)‐2‐methylpiperazin‐1‐yl]‐2‐oxoethoxy}phenyl)urea in an automated module by Mäding, P., Füchtner, F., Johannsen, B., Steinbach, J., Hilger, C. S., Friebe, M., Halks‐Miller, M., Horuk, R., Mohan, R.

“…Abstract The synthesis of 1‐(5‐chloro‐2‐{2‐[(2R)‐4‐(4‐[ 18 F]fluorobenzyl)‐2‐methylpiperazin‐1‐yl]‐2‐oxoethoxy}phenyl)urea ( [ 18 F]4 ), a potent nonpeptide…”
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Tc-99m-labeling of modified RNA by Hilger, C S, Willis, M C, Wolters, M, Pieken, W A

“…The synthesis of Tc-99m-labeled, modified RNA is reported. This new class of radiopharmaceuticals is of potential interest as target specific imaging agents…”
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12th Workshop of the Central European Division e.V. of the International Isotope Society by Snieckus, V., Geach, N. J., Randall, G. P., Winfield, C. J., Studer, A., Spivey, A. C., Jones, T., Noban, C., Ellames, G. J., Kohler, A., Wadsworth, H., Rieke-Zapp, J., Stone-Elander, S., Goehl, J., Perry, B., Windels, J., Marx, M. H., Krüger, J., Manmontri, B., Fels, G., Wüst, F., Kniess, T., Bergmann, R., Mäding, P., Füchtner, F., Hilger, C. S., Halks-Miller, M., Horuk, R., Matei, L., Postolache, C., Fugaru, V., Condac, E., Dinischiotu, A., Costache, M., Atzrodt, J., Derdau, V.

“…V Snieckus [Queen's University, Canada]—The Directed Ortho Metalation—Cross Coupling Symbiosis in Aromatic Synthesis. N Geach, GP Randall, CJ Winfield…”
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Synthesis of Tc-99m-labeled, modified RNA by Hilger, Christoph S., Willis, Michael C., Wolters, Mark, Pieken, Wolfgang A.

“…The synthesis of Tc-99m-labeled, modified RNA is reported. This new class of radiopharmaceuticals is of potential interest as target specific imaging agents…”
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