Search Results - "Hileman, Ronald E"
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Bioinformatic methods for allergenicity assessment using a comprehensive allergen database
Published in International archives of allergy and immunology (01-08-2002)“…A principal aim of the safety assessment of genetically modified crops is to prevent the introduction of known or clinically cross-reactive allergens. Current…”
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Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate
Published in Nature medicine (01-08-1997)Get full text
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Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins
Published in BioEssays (01-02-1998)“…Although interactions of proteins with glycosaminoglycans (GAGs), such as heparin and heparan sulphate, are of great biological importance, structural…”
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Thermodynamic Analysis of the Heparin Interaction with a Basic Cyclic Peptide Using Isothermal Titration Calorimetry
Published in Biochemistry (Easton) (27-10-1998)“…Brain natriuretic peptide (BNP) was examined as part of a continuing study of the interaction of proteins and peptides with the glycosaminoglycan heparin. BNP…”
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Safety Assessment of Cre Recombinase
Published in Journal of agricultural and food chemistry (01-11-2006)“…Cre recombinase, when used as a tool in agricultural biotechnology, can precisely excise DNA sequences that may be useful in the introduction of a new trait…”
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Interaction of Secretory Leukocyte Protease Inhibitor with Heparin Inhibits Proteases Involved in Asthma
Published in The Journal of biological chemistry (29-05-1998)“…Protease inhibition by secretory leukocyte protease inhibitor (SLPI) is accelerated by the sulfated polysaccharides. The nature of the SLPI-polysaccharide…”
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Isolation and characterization of heparan sulfate from crude porcine intestinal mucosal peptidoglycan heparin
Published in Carbohydrate research (16-10-1995)“…A method for the preparation of heparan sulfate from peptidoglycan heparin is described. The objective of this research was to provide a basis for the…”
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Enzymatic Preparation of Heparin Oligosaccharides Containing Antithrombin III Binding Sites
Published in The Journal of biological chemistry (13-12-1996)“…Two new oligosaccharides were prepared from heparin by its partial depolymerization using heparin lyase I (EC 4.2.2.7) in an attempt to prepare…”
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Tissue distribution of [14C]sucrose octasulfate following oral administration to rats
Published in Pharmaceutical research (01-06-2002)“…Aluminum sucrose octasulfate (SOS) is used clinically to prevent ulcers. Under physiologic conditions, the sodium salt of this drug can be formed. Our…”
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Tissue distribution and antithrombotic activity of unlabeled or 14C-labeled porcine intestinal mucosal heparin following administration to rats by the oral route
Published in Canadian journal of physiology and pharmacology (01-04-2000)“…Distribution and antithrombotic activity of orally administered unfractionated porcine heparin were studied. [14C]Heparin was prepared by de-N-acetylation of…”
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Characteristics of the eukaryotic initiation factor 2 associated 67-kDa polypeptide
Published in Biochemistry (Easton) (18-05-1993)“…A eukaryotic initiation factor 2 (eIF-2) associated 67-kDa polypeptide (p67) protects the eIF-2 alpha-subunit from eIF-2 kinase(s) catalyzed phosphorylation,…”
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Thermodynamic Characterization of the Cooperativity of 40S Complex Formation during the Initiation of Eukaryotic Protein Synthesis
Published in Biochemistry (Easton) (01-12-1994)“…The first step in mammalian protein synthesis is the formation of the 40S initiation complex, composed of the 40S ribosomal subunit (R), mRNA (M, here, a…”
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Synthesis and Characterization of Conjugates Formed between Periodate-Oxidized Ribonucleotides and Amine-Containing Fluorophores
Published in Bioconjugate chemistry (01-09-1994)“…The synthesis and purification of new fluorescently labeled derivatives of GDP and ATP are described. The fluorescent groups are coupled initially through…”
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Structural differences and the presence of unsubstituted amino groups in heparan sulphates from different tissues and species
Published in Biochemical journal (01-03-1997)“…This study presents a comparison of heparan sulphate chains isolated from various porcine and bovine tissues. 1H-NMR spectroscopy (500 MHz) was applied for…”
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Dermatan sulfate as a potential therapeutic agent
Published in General Pharmacology (01-05-1995)“…1. 1. Dermatan sulfate is a linear, sulfated polysaccharide and is a glycosaminoglycan component of several important proteoglycans. This minireview discusses…”
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Interaction of Fibroblast Growth Factor-1 and Related Peptides with Heparan Sulfate and Its Oligosaccharides
Published in Archives of biochemistry and biophysics (15-10-1997)“…Fibroblast growth factors (FGFs) are a family of angiogenic and mitogenic proteins that promote cell division. The binding of FGFs to the heparan sulfate of…”
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Preparation and structure of heparin lyase-derived heparan sulfate oligosaccharides
Published in Glycobiology (Oxford) (01-03-1997)“…Porcine intestinal mucosal heparan sulfate was exhaustively depolymerized on a large scale using beparin lyase II (heparinase II) or heparin lyase III…”
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Glycosaminoglycans Can Influence Fibroblast Growth Factor-2 Mitogenicity without Significant Growth Factor Binding
Published in Biochemical and biophysical research communications (18-06-1997)“…Fibroblast growth factors are important heparin binding, mitogenic proteins. The binding site in heparin and heparan sulfate for fibroblast growth factor-2…”
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Affinity capillary electrophoresis employing immobilized glycosaminoglycan to resolve heparin-binding peptides
Published in Electrophoresis (01-03-1998)“…A new capillary electrophoresis technique has been developed for the affinity resolution of synthetic heparin-binding peptides using an immobilized…”
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