Search Results - "Hilbert, DM"

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL by Cerutti, Andrea, Litinskiy, Mikhail B, Nardelli, Bernardetta, Hilbert, David M, He, Bing, Schaffer, Andras, Casali, Paolo

“…Immunoglobulin (Ig) class-switch DNA recombination (CSR) is thought to be highly dependent upon engagement of CD40 on B cells by CD40 ligand on T cells. We…”
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Cutting Edge: BLyS Enables Survival of Transitional and Mature B Cells Through Distinct Mediators by Hsu, Benjamin L, Harless, Susan M, Lindsley, R. Coleman, Hilbert, David M, Cancro, Michael P

“…These studies characterize BLyS responsiveness and receptor expression among transitional and mature peripheral B cells. The results show a…”
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B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels by Collins, Christopher E, Gavin, Amanda L, Migone, Thi-Sau, Hilbert, David M, Nemazee, David, Stohl, William

“…Considerable evidence points to a role for B lymphocyte stimulator (BLyS) overproduction in murine and human systemic lupus erythematosus (SLE). Nevertheless,…”
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Synthesis and release of B-lymphocyte stimulator from myeloid cells by Nardelli, Bernardetta, Belvedere, Ornella, Roschke, Viktor, Moore, Paul A., Olsen, Henrik S., Migone, Thi Sau, Sosnovtseva, Svetlana, Carrell, Jeffrey A., Feng, Ping, Giri, Judith G., Hilbert, David M.

“…B-lymphocyte stimulator (BLyS) is a recently identified novel member of the tumor necrosis factor ligand superfamily shown to exist in a membrane-bound and…”
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BLyS: Member of the Tumor Necrosis Factor Family and B Lymphocyte Stimulator by Moore, Paul A., Belvedere, Ornella, Orr, Amy, Pieri, Krystyna, LaFleur, David W., Feng, Ping, Soppet, Daniel, Charters, Meghan, Gentz, Reiner, Parmelee, David, Li, Yuling, Galperina, Olga, Giri, Judith, Roschke, Viktor, Nardelli, Bernardetta, Carrell, Jeffrey, Sosnovtseva, Svetlana, Greenfield, Wilbert, Ruben, Steven M., Olsen, Henrik S., Fikes, James, Hilbert, David M.

“…The tumor necrosis factor (TNF) superfamily of cytokines includes both soluble and membrane-bound proteins that regulate immune responses. A member of the…”
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BLyS and APRIL Form Biologically Active Heterotrimers That Are Expressed in Patients with Systemic Immune-Based Rheumatic Diseases by Roschke, Viktor, Sosnovtseva, Svetlana, Ward, Christopher D, Hong, June S, Smith, Rodger, Albert, Vivian, Stohl, William, Baker, Kevin P, Ullrich, Stephen, Nardelli, Bernardetta, Hilbert, David M, Migone, Thi-Sau

“…BLyS and APRIL are two members of the TNF superfamily that are secreted by activated myeloid cells and have costimulatory activity on B cells. BLyS and APRIL…”
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Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus by Stohl, W, Metyas, S, Tan, S-M, Cheema, G S, Oamar, B, Roschke, V, Wu, Y, Baker, K P, Hilbert, D M

“…Objective: To assess longitudinal expression of a proliferation-inducing ligand (APRIL) in patients with systemic lupus erythematosus (SLE) and its correlation…”
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Aryl-hydrocarbon Receptor-Deficient Mice Are Resistant to 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Toxicity by Fernandez-Salguero, Pedro M., Hilbert, David M., Rudikoff, Stuart, Ward, Jerrold M., Gonzalez, Frank J.

“…Acute exposure of mammals to the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) results in a diverse set of toxicologic and pathologic…”
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Competition for BLyS-mediated signaling through Bcmd/BR3 regulates peripheral B lymphocyte numbers by Harless, Susan M., Lentz, Vicky M., Sah, Alex P., Hsu, Benjamin L., Clise-Dwyer, Karen, Hilbert, David M., Hayes, Colleen E., Cancro, Michael P.

“…Striking cell losses occur during late B lymphocyte maturation [1–3], reflecting BcR-mediated selection coupled with requisites for viability promoting signals…”
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Immune System Impairment and Hepatic Fibrosis in Mice Lacking the Dioxin- Binding Ah Receptor by Fernandez-Salguero, Pedro, Pineau, Thierry, Hilbert, David M., McPhail, Timothy, Susanna S. T. Lee, Kimura, Shioko, Nebert, Daniel W., Rudikoff, Stuart, Ward, Jerrold M., Gonzalez, Frank J.

“…The aryl hydrocarbon (Ah) receptor (AHR) mediates many carcinogenic and teratogenic effects of environmentally toxic chemicals such as dioxin. An AHR-deficient…”
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BLyS and BLyS receptor expression in non-Hodgkin's lymphoma by Briones, Javier, Timmerman, John M, Hilbert, David M, Levy, Ronald

“…B Lymphocyte Stimulator (BLyS) protein and its receptor are new members of the tumor necrosis factor family, with specific effects exclusively on B cells. We…”
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Context-aware communication by Schilit, B.N., Hilbert, D.M., Trevor, J.

“…This article describes how the changing information about an individual's location, environment, and social situation can be used to initiate and facilitate…”
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Baculovirus Stimulates Antiviral Effects in Mammalian Cells by Gronowski, A M, Hilbert, D M, Sheehan, K C, Garotta, G, Schreiber, R D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Raised levels of anti-glucose-6-phosphate isomerase IgG in serum and synovial fluid from patients with inflammatory arthritis by Schaller, M, Stohl, W, Tan, S M, Benoit, V M, Hilbert, D M, Ditzel, H J

“…Background: In K/BxN mice, anti-glucose-6-phosphate isomerase (GPI) antibodies (Abs) are arthritogenic, and their transfer into naïve mice induces arthritis…”
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Interleukin 6 is essential for in vivo development of B lineage neoplasms by Hilbert, D M, Kopf, M, Mock, B A, Köhler, G, Rudikoff, S

“…Interleukin (IL) 6 has been suggested to be the major cytokine responsible for proliferation of neoplastic plasma cells in both human myeloma and mouse…”
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Web interaction using very small Internet devices by Schilit, B.N., Trevor, J., Hilbert, D.M., Tzu Khiau Koh

“…Internet-enabled cell phones typically accommodate only three to 12 text lines, and their design emphasizes portability. Web interaction has, so far, been a…”
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B Lymphocyte Stimulator Protein-Associated Increase in Circulating Autoantibody Levels May Require CD4 + T Cells: Lessons from HIV-Infected Patients by Stohl, William, Cheema, Gurtej S., Briggs, William S., Xu, Dong, Sosnovtseva, Svetlana, Roschke, Viktor, Ferrara, Dardo E., Labat, Kimberly, Sattler, Fred R., Pierangeli, Silvia S., Hilbert, David M.

“…To assess the helper T cell dependence of B lymphocyte stimulator (BLyS) protein-driven autoantibody production in vivo, serum levels of BLyS protein, total…”
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B lymphocytes from individuals with common variable immunodeficiency respond to B lymphocyte stimulator (BLyS protein) in vitro by Stewart, Donn M, McAvoy, Michael J, Hilbert, David M, Nelson, David L

“…B lymphocyte stimulator (BLyS protein) is a member of the human TNF family of ligands. BLyS induces B-lymphocyte proliferation and Ig secretion in vitro and in…”
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Discovery of high-affinity peptide binders to BLyS by phage display by Fleming, Tony J., Sachdeva, Meena, Delic, Marko, Beltzer, James, Wescott, Charles R., Devlin, Mary, Lander, Robert C., Nixon, Andrew E., Roschke, Viktor, Hilbert, David M., Sexton, Daniel J.

“…B lymphocyte stimulator (BLyS) is a tumor necrosis factor (TNF) family member and a key regulator of B cell responses. We employed a phage display‐based…”
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BLyS BINDS TO B CELLS WITH HIGH AFFINITY AND INDUCES ACTIVATION OF THE TRANSCRIPTION FACTORS NF-κB AND ELF-1 by Kanakaraj, Palanisamy, Migone, Thi-Sau, Nardelli, Bernardetta, Ullrich, Stephen, Li, Yuling, Olsen, Henrik S., Salcedo, Theodora W., Kaufman, Thomas, Cochrane, Erika, Gan, Yuxiang, Hilbert, David M., Giri, Judith

“…B lymphocyte stimulator (BLyS) is a novel member of the TNF family of proteins expressed by myeloid cells as membrane-bound and soluble forms. BLyS was shown…”
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