Search Results - "Hilberg, F"

Nintedanib selectively inhibits the activation and tumour-promoting effects of fibroblasts from lung adenocarcinoma patients by Gabasa, M, Ikemori, R, Hilberg, F, Reguart, N, Alcaraz, J

“…Background: Nintedanib is a clinically approved multikinase receptor inhibitor to treat non-small cell lung cancer with adenocarcinoma (ADC) histology in…”
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Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis by Chaudhary, N. I, Roth, G. J, Hilberg, F, Muller-Quernheim, J, Prasse, A, Zissel, G, Schnapp, A, Park, J. E

“…BIBF 1000 is a small molecule inhibitor targeting the receptor kinases of platelet-derived growth factor (PDGF), basic fibroblast growth factor and vascular…”
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Phase I clinical trial of nintedanib plus paclitaxel in early HER-2-negative breast cancer (CNIO-BR-01-2010/GEICAM-2010-10 study) by Quintela-Fandino, M, Urruticoechea, A, Guerra, J, Gil, M, Gonzalez-Martin, A, Marquez, R, Hernandez-Agudo, E, Rodriguez-Martin, C, Gil-Martin, M, Bratos, R, Escudero, M J, Vlassak, S, Hilberg, F, Colomer, R

“…Introduction: Previous small-molecule antiangiogenics have compromised chemotherapy dose intensity in breast cancer. We present a phase I trial of a novel…”
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Targeted Disruption of Mouse Fibroblast Activation Protein by Niedermeyer, J, Kriz, M, Hilberg, F, Garin-Chesa, P, Bamberger, U, Lenter, M C, Park, J, Viertel, B, Püschner, H, Mauz, M, Rettig, W J, Schnapp, A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Adjuvant inhibition of the epidermal growth factor receptor after fractionated irradiation of FaDu human squamous cell carcinoma by Krause, M, Hessel, F, Zips, D, Hilberg, F, Baumann, M

“…Experiments performed by others have shown that inhibition of EGFR before and after single dose irradiation prolonged growth delay and improved local tumour…”
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Selective inhibition of the epidermal growth factor receptor tyrosine kinase by BIBX1382BS and the improvement of growth delay, but not local control, after fractionated irradiation in human FaDu squamous cell carcinoma in the nude mouse by Baumann, M., Krause, M., Zips, D., Eicheler, W., Dörfler, A., Ahrens, J., Petersen, C., Brüchner, K., Hilberg, F.

“…Purpose: To investigate the effect of BIBX1382BS, an inhibitor of the epidermal growth factor receptor tyrosine kinase, on proliferation and clonogenic cell…”
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Expression of the fibroblast activation protein during mouse embryo development by Niedermeyer, J, Garin-Chesa, P, Kriz, M, Hilberg, F, Mueller, E, Bamberger, U, Rettig, W J, Schnapp, A

“…Human Fibroblast Activation Protein (FAP), a member of the serine prolyl oligopeptidase family, is a type II cell surface glycoprotein that acts as a…”
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Embryonic Stem Cell Virus, a Recombinant Murine Retrovirus with Expression in Embryonic Stem Cells by Grez, Manuel, Akgun, Ercan, Hilberg, Frank, Ostertag, Wolfram

“…The expression of Moloney murine leukemia virus and vectors derived from it is restricted in undifferentiated mouse embryonal carcinoma and embryonal stem (ES)…”
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BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy by Hilberg, Frank, Roth, Gerald J, Krssak, Martin, Kautschitsch, Susanna, Sommergruber, Wolfgang, Tontsch-Grunt, Ulrike, Garin-Chesa, Pilar, Bader, Gerd, Zoephel, Andreas, Quant, Jens, Heckel, Armin, Rettig, Wolfgang J

“…Inhibition of tumor angiogenesis through blockade of the vascular endothelial growth factor (VEGF) signaling pathway is a novel treatment modality in oncology…”
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Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells by Chen, J, Stewart, V, Spyrou, G, Hilberg, F, Wagner, E F, Alt, F W

“…To determine the potential roles of c-jun in lymphocyte development, we generated somatic chimeric mice by injecting homozygous c-jun mutant embryonic stem…”
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Functional Analysis of a Retroviral Host-Range Mutant: Altered Long Terminal Repeat Sequences Allow Expression in Embryonal Carcinoma Cells by Hilberg, Frank, Stocking, Carol, Ostertag, Wolfram, Grez, Manuel

“…A retroviral host-range neomycin-resistant myeloproliferative sarcoma virus mutant, which is expressed in the embryonal carcinoma cell lines F9 and PCC4aza1R,…”
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Retroviral Mutants Efficiently Expressed in Embryonal Carcinoma Cells by Franz, Thomas, Hilberg, Frank, Seliger, Barbara, Stocking, Carol, Ostertag, Wolfram

“…The myeloproliferative sarcoma virus (MPSV) is a unique member of the Moloney murine sarcoma virus family. Due to mutations in the U3 region of its long…”
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CD44-Deficient Mice Develop Normally with Changes in Subpopulations and Recirculation of Lymphocyte Subsets by Protin, Ursula, Schweighoffer, Tamas, Jochum, Wolfram, Hilberg, Frank

“…Cell adhesion molecules are considered to be pivotal elements required for proper embryo development. The transmembrane glycoprotein CD44, which is expressed…”
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DMBT1 Confers Mucosal Protection In Vivo and a Deletion Variant Is Associated With Crohn’s Disease by Renner, Marcus, Bergmann, Gaby, Krebs, Inge, End, Caroline, Lyer, Stefan, Hilberg, Frank, Helmke, Burkhard, Gassler, Nikolaus, Autschbach, Frank, Bikker, Floris, Strobel–Freidekind, Olga, Gronert–Sum, Sabine, Benner, Axel, Blaich, Stephanie, Wittig, Rainer, Hudler, Melanie, Ligtenberg, Antoon J, Madsen, Jens, Holmskov, Uffe, Annese, Vito, Latiano, Anna, Schirmacher, Peter, Amerongen, Arie V. Nieuw, D’Amato, Mauro, Kioschis, Petra, Hafner, Mathias, Poustka, Annemarie, Mollenhauer, Jan

“…Background & Aims: Impaired mucosal defense plays an important role in the pathogenesis of Crohn’s disease (CD), one of the main subtypes of inflammatory bowel…”
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Cloning of hexokinase structural genes from Saccharomyces cerevisiae mutants with regulatory mutations responsible for glucose repression by Entian, K D, Hilberg, F, Opitz, H, Mecke, D

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Functions of c-Jun in Liver and Heart Development by Eferl, Robert, Sibilia, Maria, Hilberg, Frank, Fuchsbichler, Andrea, Kufferath, Iris, Guertl, Barbara, Zenz, Rainer, Wagner, Erwin F., Zatloukal, Kurt

“…Mice lacking the AP-1 transcription factor c-Jun die around embryonic day E13.0 but little is known about the cell types affected as well as the cause of…”
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c-Jun is essential for normal mouse development and hepatogenesis by Hilberg, Frank, Aguzzi, Adriano, Howells, Norma, Wagner, Erwin F

“…The proto-oncogene c-jun is the cellular homologue of v-jun, the transforming oncogene of the avian sarcoma virus 17 (ref. 1). c-jun encodes one major…”
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CD44 is a determinant of inflammatory bone loss by Hayer, Silvia, Steiner, Günter, Görtz, Birgit, Reiter, Erika, Tohidast-Akrad, Makiyeh, Amling, Michael, Hoffmann, Oskar, Redlich, Kurt, Zwerina, Jochen, Skriner, Karl, Hilberg, Frank, Wagner, Erwin F, Smolen, Josef S, Schett, Georg

“…Chronic inflammation is a major trigger of local and systemic bone loss. Disintegration of cell-matrix interaction is a prerequisite for the invasion of…”
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unusual hexose-ATP-kinase with two catalytic sites and a role in carbon catabolite repression in the yeast Schwanniomyces occidentalis by McCann, A.K, Hilberg, F, Kenworthy, P, Barnett, J.A

“…School of Biological Sciences, University of East Anglia, Norwich NR4 7TJ, UK {Received 26 June 1986 ABSTRACT The hexose-ATP-kinase of wild-type Schwanniomyces…”
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Targeting receptor kinases by a novel indolinone derivative in multiple myeloma: abrogation of stroma-derived interleukin-6 secretion and induction of apoptosis in cytogenetically defined subgroups by Bisping, Guido, Kropff, Martin, Wenning, Doris, Dreyer, Britta, Bessonov, Sergey, Hilberg, Frank, Roth, Gerald J., Munzert, Gerd, Stefanic, Martin, Stelljes, Matthias, Scheffold, Christian, Müller-Tidow, Carsten, Liebisch, Peter, Lang, Nicola, Tchinda, Jöelle, Serve, Hubert L., Mesters, Rolf M., Berdel, Wolfgang E., Kienast, Joachim

“…In multiple myeloma (MM), both vascular endothelial (VEGF) and basic fibroblast growth factor (bFGF) promote tumor growth and survival. We have used the novel…”
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