Search Results - "Hikichi, Yuta"
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Mechanistic Analysis of the Broad Antiretroviral Resistance Conferred by HIV-1 Envelope Glycoprotein Mutations
Published in mBio (12-01-2021)“…Despite the effectiveness of antiretroviral (ARV) therapy, virological failure can occur in some HIV-1-infected patients in the absence of mutations in drug…”
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Impaired protective role of HLA-B57:01/58:01 in HIV-1 CRF01_AE infection: a cohort study in Vietnam
Published in International journal of infectious diseases (01-03-2023)“…•The protective effect of HLA-B*57:01/58:01 on HIV-1 CRF01_AE infection was examined.•The protective impact is impaired against CRF01_AE…”
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Exploring HIV-1 Maturation: A New Frontier in Antiviral Development
Published in Viruses (06-09-2024)“…HIV-1 virion maturation is an essential step in the viral replication cycle to produce infectious virus particles. Gag and Gag-Pol polyproteins are assembled…”
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Increased HIV-1 sensitivity to neutralizing antibodies by mutations in the Env V3-coding region for resistance to CXCR4 antagonists
Published in Journal of general virology (01-09-2016)“…HIV-1 passage in cell culture in the presence of chemokine receptor antagonists can result in selection of viruses with env mutations that confer resistance to…”
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HIV-1 Matrix Trimerization-Impaired Mutants Are Rescued by Matrix Substitutions That Enhance Envelope Glycoprotein Incorporation
Published in Journal of virology (12-12-2019)“…The matrix (MA) domain of HIV-1 Gag plays key roles in virus assembly by targeting the Gag precursor to the plasma membrane and directing the incorporation of…”
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Ignition and supersonic combustion behavior of liquid ethanol in a scramjet model combustor with cavity flame holder
Published in Proceedings of the Combustion Institute (01-01-2015)“…This study carried out experiments to investigate the combustion behavior of ethanol at Mach 2.0 and stagnation temperatures between 1800 and 2200K using a…”
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HIV-1 matrix mutations that alter gag membrane binding modulate mature core formation and post-entry events
Published in Virology (New York, N.Y.) (01-06-2019)“…The matrix (MA) domain of HIV-1 Gag directs membrane binding of the Gag precursor polyprotein during the late events of virus replication. However, the effects…”
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Neutral sphingomyelinase 2 is required for HIV-1 maturation
Published in Proceedings of the National Academy of Sciences - PNAS (11-07-2023)“…HIV-1 assembly occurs at the inner leaflet of the plasma membrane (PM) in highly ordered membrane microdomains. The size and stability of membrane microdomains…”
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Epistatic pathways can drive HIV-1 escape from integrase strand transfer inhibitors
Published in Science advances (01-03-2024)“…People living with human immunodeficiency virus (HIV) receiving integrase strand transfer inhibitors (INSTIs) have been reported to experience virological…”
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Cronkhite-Canada syndrome associated with myelodysplastic syndrome
Published in World journal of gastroenterology : WJG (14-12-2009)“…We report a case of Cronkhite-Canada syndrome (CCS) associated with myelodysplastic syndrome (MDS). A 54-year-old woman, diagnosed as MDS the prior year after…”
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