Biomarkers of Renal Function: Towards Clinical Actionability

This review provides an overview of the clinical value of the most relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and chronic kidney disease. We categorize biomarkers according to their actionability, in terms of a documented response to treatment in relatio...

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Bibliographic Details
Published in:	Clinical pharmacology and therapeutics Vol. 102; no. 3; pp. 481 - 492
Main Authors:	Binnenmars, S Heleen, Hijmans, RS, Navis, G, Borst, MH
Format:	Journal Article
Language:	English
Published:	United States 01-09-2017
Subjects:	Acute Kidney Injury - physiopathology Biomarkers - metabolism Humans Kidney - metabolism Kidney - physiopathology Kidney Function Tests Renal Insufficiency, Chronic - physiopathology
Online Access:	Get full text
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Summary:	This review provides an overview of the clinical value of the most relevant renal biomarkers, focusing on two main clinical conditions: acute kidney injury and chronic kidney disease. We categorize biomarkers according to their actionability, in terms of a documented response to treatment in relation to outcomes. Furthermore, we introduce a new category of renal biomarkers, metabolic biomarkers, and underscore their capacity to be highly actionable.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0009-9236 1532-6535
DOI:	10.1002/cpt.765