Search Results - "Higuchi, William I"

Efficacy of the injectable calcium phosphate ceramics suspensions containing magnesium, zinc and fluoride on the bone mineral deficiency in ovariectomized rats by Otsuka, Makoto, Oshinbe, Ayako, Legeros, Racquel Z, Tokudome, Yoshihiro, Ito, Atsuo, Otsuka, Kuniko, Higuchi, William I

“…The purpose of this study was to evaluate the therapeutic efficacy of a new calcium phosphate (CaP)-based formulation in improving the bone mineral deficiency…”
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Effect of geometrical structure on the in vivo quality change of a three-dimensionally perforated porous bone cell scaffold made of apatite/collagen composite by Otsuka, Makoto, Nakagawa, Hidenori, Otsuka, Kuniko, Ito, Atsuo, Higuchi, William I.

“…Biodegradable artificial bone blocks with interconnective pores were prepared using a self‐setting apatite/collagen composite cement as a cell scaffold for…”
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Effects of oxygen-containing terpenes as skin permeation enhancers on the lipoidal pathways of human epidermal membrane by Chantasart, Doungdaw, Pongjanyakul, Thaned, Higuchi, William I, Li, S Kevin

“…The present study investigated the effects of oxygen-containing terpenes as skin permeation enhancers on the lipoidal pathways of human epidermal membrane…”
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Effect of Geometrical Structure on the Biodegradation of a Three-Dimensionally Perforated Porous Apatite/Collagen Composite Bone Cell Scaffold by Hamada, Hideyuki, Ohshima, Hiroyuki, Ito, Atsuo, Higuchi, William I., Otsuka, Makoto

“…A Biodegradable artificial bone with inter-connective pores was prepared using a self-setting apatite/collagen composite cement as a cell scaffold for bone…”
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Comparison of the effects of chemical permeation enhancers on the lipoidal pathways of human epidermal membrane and hairless mouse skin and the mechanism of enhancer action by Chantasart, Doungdaw, Sa-Nguandeekul, Piyanuch, Prakongpan, Sompol, Li, S Kevin, Higuchi, William I

“…Previously, the effects of chemical permeation enhancers upon the permeability of the lipoidal pathway of hairless mouse skin (HMS) were investigated and a…”
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Evaluation of constant current alternating current iontophoresis for transdermal drug delivery by Yan, Guang, Li, S. Kevin, Higuchi, William I.

“…Previous studies in our laboratory have demonstrated that alternating current (AC) iontophoresis can significantly decrease skin electric resistance and…”
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Effect of nanostructure on biodegradation behaviors of self-setting apatite/collagen composite cements containing vitamin K2 in rats by Otsuka, Makoto, Kuninaga, Tomoaki, Otsuka, Kuniko, Higuchi, William I.

“…Apatite cement and collagen were combined by a mechanochemical method to create a new self‐setting apatite/collagen composite cement, and menatetrenone (VK2)…”
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Influence of crystallite microstrain on surface complexes governing the metastable equilibrium solubility behavior of carbonated apatites by Papangkorn, Kongnara, Yan, Guang, Heslop, Dustin D., Moribe, Kunikazu, Baig, Arif A., Otsuka, Makoto, Higuchi, William I.

“…This study was on the influence of the mineral phase crystallite microstrain (CM) on the nature of the surface complex (SC) governing the metastable…”
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Effects of electrophoresis and electroosmosis during alternating current iontophoresis across human epidermal membrane by Yan, Guang, Peck, Kendall D, Zhu, Honggang, Higuchi, William I, Li, S Kevin

“…Previous studies in our laboratory have demonstrated that skin electrical resistance can be controlled by an alternating current (AC) electric field. By…”
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Novel Dexamethasone Sodium Phosphate Treatment (DSP-Visulex) for Noninfectious Anterior Uveitis: A Randomized Phase I/II Clinical Trial by Papangkorn, Kongnara, Truett, Kim R., Vitale, Albert T., Jhaveri, Chirag, Scales, David K., Foster, C. Stephen, Montieth, Alyssa, Higuchi, John W., Brar, Balbir, Higuchi, William I.

“…Purpose: Frequent steroid drops represent a challenge in patient compliance. This study evaluated the safety and efficacy of 5 minute topical dexamethasone…”
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Capric Acid Absorption in the Presence of Hydroxypropyl-β-Cyclodextrin in the Rat Ileum using the In Situ Single-Pass Perfusion Technique by Hymas, Richard V, Ho, Norman F H, Higuchi, William I

“…The purpose of the present study was to gain quantitative mechanistic insight into the role cyclodextrin carriers may play in the intestinal absorption of…”
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Influences of alkyl group chain length and polar head group on chemical skin permeation enhancement by Warner, K S, Li, S K, Higuchi, W I

“…Previous investigations in our laboratory on the influence of the n-alkanols and the 1-alkyl-2-pyrrolidones as skin permeation enhancers for steroid molecules…”
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Quantitative study of electrophoretic and electroosmotic enhancement during alternating current iontophoresis across synthetic membranes by Yan, Guang, Li, S Kevin, Peck, Kendall D, Zhu, Honggang, Higuchi, William I

“…One of the primary safety and tolerability limitations of direct current iontophoresis is the potential for electrochemical burns associated with the necessary…”
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Osteotropic Peptide That Differentiates Functional Domains of the Skeleton by Wang, Dong, Miller, Scott C, Shlyakhtenko, Luda S, Portillo, Alexander M, Liu, Xin-Ming, Papangkorn, Kongnara, Kopečková, Pavla, Lyubchenko, Yuri, Higuchi, William I, Kopeček, Jindřich

“…HPMA copolymer−d-aspartic acid octapeptide (D-Asp8) conjugates have been found to target the entire skeleton after systemic administration. In a recent study…”
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Effect of geometrical structure on drug release rate of a three-dimensionally perforated porous apatite/collagen composite cement by Otsuka, Makoto, Nakagawa, Hidenori, Ito, Atsuo, Higuchi, William I

“…To improve the biocompatibility, inter-connective pore structure, and drug delivery ability of self-setting apatite/collagen composite cement (ACC), a…”
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Chemometric evaluation of physicochemical properties of carbonated-apatitic preparations by Fourier transform infrared spectroscopy by Otsuka, Makoto, Papangkorn, Kongnara, Baig, Arif A., Higuchi, William I.

“…The purpose of this study was to develop a simple and quick method of evaluating the physicochemical properties of carbonated apatite preparations (CAP) as an…”
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Transscleral iontophoretic and intravitreal delivery of a macromolecule: Study of ocular distribution in vivo and postmortem with MRI by Molokhia, Sarah A., Jeong, Eun-Kee, Higuchi, William I., Li, S. Kevin

“…The distribution and clearance of macromolecules in ocular delivery are not well understood. It has been hypothesized that iontophoresis can enhance…”
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Mechanistic aspects of iontophoresis in human epidermal membrane by Higuchi, William I, Li, S.Kevin, Ghanem, Abdel-Halim, Zhu, Honggang, Song, Yang

“…A large number of factors are involved in the movement of ions and molecules across human epidermal membrane (HEM) under the influence of an electric field…”
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Ion-exchange membrane assisted transdermal iontophoretic delivery of salicylate and acyclovir by Xu, Qingfang, Ibrahim, Sarah A., Higuchi, William I., Li, S. Kevin

“…The presence of endogenous competing counterions is a main reason for the generally low efficiency of transdermal iontophoretic drug delivery. The objective of…”
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Transport behavior of hairless mouse skin during constant current DC iontophoresis I: baseline studies by Liddell, Mark R, Li, S Kevin, Higuchi, William I

“…The fluxes of charged and nonionic molecules across hairless mouse skin (HMS) were induced by direct current iontophoresis and used to characterize the…”
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