Search Results - "Highfield, A"
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Genotyping an Emiliania huxleyi (prymnesiophyceae) bloom event in the North Sea reveals evidence of asexual reproduction
Published in Biogeosciences (29-09-2014)“…Due to the unprecedented rate at which our climate is changing, the ultimate consequence for many species is likely to be either extinction or migration to an…”
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The sustainability of the critical care workforce
Published in Nursing in critical care (01-01-2019)Get full text
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3
Stress and Fear: Clinical Implications for Providers and Patients (in the Time of COVID-19 and Beyond)
Published in Mayo Clinic proceedings (01-11-2020)“…In light of the coronavirus disease 2019 pandemic, we explore the role of stress, fear, and the impact of positive and negative emotions on health and disease…”
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Flaccid Brachial Monoplegia As Initial Presentation in a Patient With Progressive Multifocal Leukoencephalopathy
Published in Curēus (Palo Alto, CA) (17-04-2022)“…Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease caused by activation of John Cunningham virus (JCV) replication in the setting of…”
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5
Reinstatement of cocaine seeking in 129X1/SvJ mice: effects of cocaine priming, cocaine cues and food deprivation
Published in Psychopharmacologia (01-06-2002)“…The mechanisms underlying relapse to cocaine seeking induced by exposure to priming cocaine injections, cues associated with cocaine self-administration and…”
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Impact of Reirradiation Utilizing Fractionated Stereotactic Radiotherapy for Recurrent Glioblastoma
Published in Curēus (Palo Alto, CA) (26-01-2024)“…Patients with recurrent glioblastoma (GBM) have limited treatment options. This study determined whether patients with recurrent GBM treated with initial…”
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Alleviation of X-Irradiation-Based Deficit in Memory-Based Learning by D-Amphetamine: Suggestions for Attention Deficit-Hyperactivity Disorder
Published in Proceedings of the National Academy of Sciences - PNAS (12-05-1998)“…Selective exposure to x-irradiation during infancy, from postnatal days (PND) 2-11 in the rat, results in severe hippocampal granule cell hypoplasia…”
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Synthesis, hydroxyl radical production and cytotoxicity of analogues of bleomycin
Published in Bioorganic & medicinal chemistry (01-05-2000)“…Two pyridine analogues of the metal complexing region of the anticancer drug bleomycin and two related but deactivated prodrugs have been linked to a…”
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The NMDA Antagonist MK-801 Affects Nonspatial Learning in Preweanling Rats
Published in Behavioral neuroscience (01-04-1996)“…The N -methyl- d -aspartate (NMDA) subtype of the excitatory amino acid receptor has been implicated in several kinds of learning and memory, as well as in…”
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A randomized controlled trial of interim methadone maintenance: 10-Month follow-up
Published in Drug and alcohol dependence (05-01-2007)“…Abstract This study compares interim maintenance (IM) to a waiting list condition at an opioid treatment program (OTP). As defined by US federal regulations,…”
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Effects of Early Postnatal Alcohol Exposure on Learning in the Developing Rat: Replication With Intubation Method of Delivery
Published in Alcoholism, clinical and experimental research (01-06-1999)“…Early postnatal exposure to alcohol during early development produces deficits in learned persistence, as reflected in the partial reinforcement extinction…”
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Ng-nitro-L-arginine, an NOS inhibitor, reduces tolerance to morphine in the rat locus coeruleus
Published in Synapse (New York, N.Y.) (01-07-1998)“…Ng‐nitro‐L‐arginine (L‐NArg), a potent nitric oxide synthase inhibitor, has been implicated as a potential mechanism for attenuating the development of…”
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Intravenous and intranasal heroin-dependent treatment-seekers: characteristics and treatment outcome
Published in Addiction (Abingdon, England) (01-11-2007)“…ABSTRACT Aims This study compared the characteristics of intravenous (i.v.) and intranasal (i.n.) heroin users seeking methadone treatment, and their response…”
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Reversal of a Postnatal Alcohol-Induced Deficit in Learned Persistence in the Rat by d-Amphetamine
Published in Alcoholism, clinical and experimental research (01-06-1999)“…Periodic (high peak) exposure to alcohol during early infancy in the rat has been shown to disrupt the partial reinforcement extinction effect (PREE), a…”
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Synthesis and properties of prodrugs activated in hypoxia to give bleomycin analogues
Published in Bioorganic & medicinal chemistry letters (22-09-1998)“…Prodrugs bioreductively activated to bleomycin analogues are reported. The production of hydroxyl radicals in the presence of Fe(II) and dioxygen by both the…”
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Scaling-up interim methadone maintenance: Treatment for 1,000 heroin-addicted individuals
Published in Journal of substance abuse treatment (01-12-2009)“…Abstract The objectives of this study were to determine the following: (a) the feasibility of expanding interim methadone treatment (IM), (b) the impact of IM…”
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Brief vs. Extended Buprenorphine Detoxification in a Community Treatment Program: Engagement and Short-Term Outcomes
Published in The American journal of drug and alcohol abuse (01-01-2009)“…Background: Despite evidence supporting the efficacy of buprenorphine relative to established detoxification agents such as clonidine, little research has…”
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A Randomized Controlled Trial of Interim Methadone Maintenance
Published in Archives of general psychiatry (01-01-2006)“…CONTEXT Effective alternatives to long waiting lists for entry into methadone hydrochloride maintenance treatment are needed to reduce the complications of…”
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Extracellular characteristics of putative cholinergic neurons in the rat laterodorsal tegmental nucleus
Published in Brain research (13-09-1991)“…The extracellular electrophysiological properties of neurons in the laterodorsal tegmental nucleus (LDT), a major source of cholinergic afferents to the…”
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The role of a conserved inter-transmembrane domain interface in regulating alpha(2a)-adrenergic receptor conformational stability and cell-surface turnover
Published in Molecular pharmacology (01-04-2001)“…Functional and structural data from G protein-coupled receptors (GPCR) predict that transmembrane-domain (TM)2 is adjacent to TM7 within the GPCR structure,…”
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