Search Results - "Higgs, Nathalie"
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Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites
Published in Cell reports (Cambridge) (04-10-2016)“…Correct mitochondrial distribution is critical for satisfying local energy demands and calcium buffering requirements and supporting key cellular processes…”
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Miro1‐dependent mitochondrial positioning drives the rescaling of presynaptic Ca2+ signals during homeostatic plasticity
Published in EMBO reports (01-02-2017)“…Mitochondrial trafficking is influenced by neuronal activity, but it remains unclear how mitochondrial positioning influences neuronal transmission and…”
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Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition
Published in Cell reports (Cambridge) (19-02-2019)“…Altered excitatory/inhibitory (E/I) balance is implicated in neuropsychiatric and neurodevelopmental disorders, but the underlying genetic etiology remains…”
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Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling
Published in The Journal of neuroscience (02-12-2015)“…It is fast emerging that maintaining mitochondrial function is important for regulating astrocyte function, although the specific mechanisms that govern…”
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Mitochondrial trafficking in neurons and the role of the Miro family of GTPase proteins
Published in Biochemical Society transactions (01-12-2013)“…Correct mitochondrial dynamics are essential to neuronal function. These dynamics include mitochondrial trafficking and quality-control systems that maintain a…”
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Quantum dot conjugated nanobodies for multiplex imaging of protein dynamics at synapses
Published in Nanoscale (01-01-2018)“…Neurons communicate with each other through synapses, which show enrichment for specialized receptors. Although many studies have explored spatial enrichment…”
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The importance of interdisciplinary communication in the neck lump clinic to improve efficiency and diagnosis in an unusual lymphoma presentation
Published in Advances in oral and maxillofacial surgery (01-06-2024)“…The importance of close and collaborative working between surgeons and radiologists in a one stop neck lump clinic is essential to ensure the correct diagnosis…”
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Miro1-dependent mitochondrial dynamics in parvalbumin interneurons
Published in eLife (30-06-2021)“…The spatiotemporal distribution of mitochondria is crucial for precise ATP provision and calcium buffering required to support neuronal signaling. Fast-spiking…”
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Management of mandibular fracture in a one-year-old child: A case report
Published in Advances in oral and maxillofacial surgery (01-01-2021)“…Mandibular fracture in the very young children is rare, and may present with significant diagnostic and treatment decision-making challenges to the clinicians…”
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132. Management of incidental thyroid nodules vs palpable thyroid nodules
Published in British journal of oral & maxillofacial surgery (01-12-2022)Get full text
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30. Audit of diagnostic accuracy of ultrasound guided fine needle aspiration and core biopsy of head and neck lumps
Published in British journal of oral & maxillofacial surgery (01-12-2022)Get full text
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Miro1‐dependent mitochondrial positioning drives the rescaling of presynaptic Ca 2+ signals during homeostatic plasticity
Published in EMBO reports (01-02-2017)Get full text
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Miro Dependent Mitochondrial Positioning Is Important for Neuronal Development and Maintenance
Published 01-01-2016“…Correct dendritic development is important for the formation of neuronal circuits. Dendritic arbors form an extensive, complex network with spatially distinct…”
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Dissertation