Search Results - "Higgins, Vincent J"

Cells Have Distinct Mechanisms to Maintain Protection against Different Reactive Oxygen Species: Oxidative-Stress-Response Genes by Thorpe, Geoffrey W., Fong, Chii S., Alic, Nazif, Higgins, Vincent J., Dawes, Ian W., Lindquist, Susan L.

“…The complete set of viable deletion strains in Saccharomyces cerevisiae was screened for sensitivity of mutants to five oxidants to identify cell functions…”
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Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils by Kemp, Sharon, Wheate, Nial J, Wang, Shaoyu, Collins, J Grant, Ralph, Stephen F, Day, Anthony I, Higgins, Vincent J, Aldrich-Wright, Janice R

“…The partial encapsulation of platinum(II)-based DNA intercalators of the type [Pt(5-Cl-phen)(ancillary ligand)](2+), where 5-Cl-phen is…”
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Identification of a protein with antioxidant activity that is important for the protection against beer ageing by Wu, Ming J, Clarke, Frank M, Rogers, Peter J, Young, Paul, Sales, Narelle, O'Doherty, Patrick J, Higgins, Vincent J

“…This study was carried out with fresh Australian lager beer which was sampled directly off the production line, the same samples aged for 12 weeks at 30 °C,…”
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Yeast genome-wide expression analysis identifies a strong ergosterol and oxidative stress response during the initial stages of an industrial lager fermentation by Higgins, V.J, Beckhouse, A.G, Oliver, A.D, Rogers, P.J, Dawes, I.W

“…Genome-wide expression analysis of an industrial strain of Saccharomyces cerevisiae during the initial stages of an industrial lager fermentation identified a…”
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Different reactive oxygen species lead to distinct changes of cellular metal ions in the eukaryotic model organism Saccharomyces cerevisiae by Wu, Ming J, O'Doherty, Patrick J, Murphy, Patricia A, Lyons, Victoria, Christophersen, Melinda, Rogers, Peter J, Bailey, Trevor D, Higgins, Vincent J

“…Elemental uptake and export of the cell are tightly regulated thereby maintaining the ionomic homeostasis. This equilibrium can be disrupted upon exposure to…”
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Superoxide radicals have a protective role during H2O2 stress by Thorpe, Geoffrey W, Reodica, Mayfebelle, Davies, Michael J, Heeren, Gino, Jarolim, Stefanie, Pillay, Bethany, Breitenbach, Michael, Higgins, Vincent J, Dawes, Ian W

“…Reactive oxygen species (ROS) consist of potentially toxic, partly reduced oxygen species and free radicals. After H(2)O(2) treatment, yeast cells…”
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Essential Role of One-carbon Metabolism and Gcn4p and Bas1p Transcriptional Regulators during Adaptation to Anaerobic Growth of Saccharomyces cerevisiae by Tsoi, Bonny M., Beckhouse, Anthony G., Gelling, Cristy L., Raftery, Mark J., Chiu, Joyce, Tsoi, Abraham M., Lauterbach, Lars, Rogers, Peter J., Higgins, Vincent J., Dawes, Ian W.

“…The transcriptional activator Gcn4p is considered the master regulator of amino acid metabolism in Saccharomyces cerevisiae and is required for the…”
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Genome-wide transcriptional responses to a lipid hydroperoxide: adaptation occurs without induction of oxidant defenses by Alic, Nazif, Felder, Thomas, Temple, Mark D, Gloeckner, Christian, Higgins, Vincent J, Briza, Peter, Dawes, Ian W

“…Free radicals can initiate the oxidation of polyunsaturated fatty acids in cells through the process of lipid peroxidation. The genome-wide transcriptional…”
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Lipid Hydroperoxides Activate the Mitogen-activated Protein Kinase Mpk1p in Saccharomyces cerevisiae by Alic, Nazif, Higgins, Vincent J., Pichova, Alena, Breitenbach, Michael, Dawes, Ian W.

“…Saccharomyces cerevisiae is capable of responding to oxidants, including lipid peroxidation products. We investigate here the role of the mitogen-activated…”
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A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Compound in Comparison to Cisplatin by Wright, Elise P, Padula, Matthew P, Higgins, Vincent J, Aldrich-Wright, Janice R, Coorssen, Jens R

“…Many clinically available anticancer compounds are designed to target DNA. This commonality of action often yields overlapping cellular response mechanisms and…”
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Application of genome-wide expression analysis to identify molecular markers useful in monitoring industrial fermentations by Higgins, V.J, Rogers, P.J, Dawes, I.W

“…Genome-wide expression analysis of an industrial strain of Saccharomyces cerevisiae identified the YOR387c and YGL258w homologues as highly inducible in…”
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Characterization of the putative maltose transporters encoded by YDL247w and YJR160c by Day, Rachel E., Higgins, Vincent J., Rogers, Peter J., Dawes, Ian W.

“…The maltose permease family of Saccharomyces cerevisiae comprises five proteins, three of which are characterized, MAL31, MAL61 and AGT1 and two putative…”
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Molecular Analysis of Maltotriose Transport and Utilization by Saccharomyces cerevisiae by DAY, Rachel E, ROGERS, Peter J, DAWES, Ian W, HIGGINS, Vincent J

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress by Higgins, Vincent J., Alic, Nazif, Thorpe, Geoffrey W., Breitenbach, Michael, Larsson, Veronica, Dawes, Ian W.

“…Ascertaining the impact of inhibitors on the growth phenotype of yeast mutants can beuseful in elucidating the function of genes within the cell. Microtitre…”
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Generation of a Novel Saccharomyces cerevisiae Strain That Exhibits Strong Maltose Utilization and Hyperosmotic Resistance Using Nonrecombinant Techniques by HIGGINS, Vincent J, BELL, Philip J. L, DAWES, Ian W, ATTFIELD, Paul V

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles by Wheate, Nial J, Taleb, Robin I, Krause-Heuer, Anwen M, Cook, Rebekah L, Wang, Shaoyu, Higgins, Vincent J, Aldrich-Wright, Janice R

“…Platinum(II)-based DNA intercalators where the intercalating ligand is 1,10-phenanthroline or a phenanthroline derivative and where the ancillary ligand is…”
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antioxidant screening assay based on oxidant-induced growth arrest in Saccharomyces cerevisiae by Wu, Ming J, O'Doherty, Patrick J, Fernandez, Harvey R, Lyons, Victoria, Rogers, Peter J, Dawes, Ian W, Higgins, Vincent J

“…This report describes a biological screening system to measure the antioxidant capacity of compounds using the oxidant-induced growth arrest response of…”
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The Saccharomyces cerevisiae transcriptome as a mirror of phytochemical variation in complex extracts of Equisetum arvense from America, China, Europe and India by Cook, Rebekah, Hennell, James R, Lee, Samiuela, Khoo, Cheang S, Carles, Maria C, Higgins, Vincent J, Govindaraghavan, Suresh, Sucher, Nikolaus J

“…Pattern-oriented chemical profiling is increasingly being used to characterize the phytochemical composition of herbal medicines for quality control purposes…”
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Genetic evidence that high noninduced maltase and maltose permease activities, governed by MALx3-encoded transcriptional regulators, determine efficiency of gas production by baker's yeast in unsugared dough by Higgins, V.J, Braidwood, M, Bell, P, Bissinger, P, Dawes, I.W, Attfield, P.V

“…Strain selection and improvement in the baker's yeast industry have aimed to increase the speed of maltose fermentation in order to increase the leavening…”
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Adaptation to hydrogen peroxide in Saccharomyces cerevisiae: The role of NADPH-generating systems and the SKN7 transcription factor by Ng, Chong-Han, Tan, Shi-Xiong, Perrone, Gabriel G., Thorpe, Geoffrey W., Higgins, Vincent J., Dawes, Ian W.

“…A total of 286 H 2O 2-sensitive Saccharomyces cerevisiae deletion mutants were screened to identify genes involved in cellular adaptation to H 2O 2 stress…”
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