Search Results - "Higgins, Emily A."
-
1
Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics
Published in TrAC, Trends in analytical chemistry (Regular ed.) (01-12-2018)“…Due to excellent separation capacity for complex mixtures of chemicals, comprehensive two-dimensional gas chromatography (GC × GC) is being utilized with…”
Get full text
Journal Article -
2
Inhibition of Fungal Growth and Induction of a Novel Volatilome in Response to Chromobacterium vaccinii Volatile Organic Compounds
Published in Frontiers in microbiology (20-05-2020)“…The study of chemical bioactivity in the rhizosphere has recently broadened to include microbial metabolites, and their roles in niche construction and…”
Get full text
Journal Article -
3
Peripheral infection and aging interact to impair hippocampal memory consolidation
Published in Neurobiology of aging (01-05-2006)“…We report that a peripheral injection of Escherichia coli produces both anterograde and retrograde amnesia in 24 month old, but not 3 month old rats for…”
Get full text
Journal Article -
4
Life Cycle Dominates the Volatilome Character of Dimorphic Fungus Coccidioides spp
Published in mSphere (14-04-2021)“…Valley fever (coccidioidomycosis) is an endemic fungal pneumonia of the North and South American deserts. The causative agents of Valley fever are the…”
Get full text
Journal Article -
5
The Role of the Dorsal Hippocampus in the Acquisition and Retrieval of Context Memory Representations
Published in The Journal of neuroscience (10-03-2004)“…It is argued that the hippocampus contributes to contextual fear conditioning by supporting the acquisition of a conjunctive memory representation of context,…”
Get full text
Journal Article -
6
Volatile Metabolites in Lavage Fluid Are Correlated with Cytokine Production in a Valley Fever Murine Model
Published in Journal of fungi (Basel) (01-01-2023)“…Coccidioides immitis and Coccidioides posadasii are soil-dwelling fungi of arid regions in North and South America that are responsible for Valley fever…”
Get full text
Journal Article -
7
The Role of Dorsal Hippocampus and Basolateral Amygdala NMDA Receptors in the Acquisition and Retrieval of Context and Contextual Fear Memories
Published in Behavioral neuroscience (01-08-2007)“…The authors used 3-phase context preexposure facilitation methodology to study the contribution of N -methyl- d -aspartate (NMDA) receptors in dorsal…”
Get full text
Journal Article -
8
Time course of hippocampal IL-1 β and memory consolidation impairments in aging rats following peripheral infection
Published in Brain, behavior, and immunity (01-01-2009)“…Abstract We previously reported that aging F344XBN rats are more vulnerable to disruptions of memory consolidation processes following an injection of…”
Get full text
Journal Article -
9
Synaptic and intrinsic balancing during postnatal development in rat pups exposed to valproic acid in utero
Published in The Journal of neuroscience (14-09-2011)“…Valproic acid (VPA) is among the most teratogenic of commonly prescribed anticonvulsants, increasing the risk in humans of major malformations and impaired…”
Get full text
Journal Article -
10
New Breath Diagnostics for Fungal Disease
Published in Current clinical microbiology reports (01-06-2024)“…Purpose of Review Diagnosis of fungal disease etiology is often difficult, compounded by inaccurate or delayed diagnostic methods. Breath-based biomarkers are…”
Get full text
Journal Article -
11
Addressing Missing Data in GC × GC Metabolomics: Identifying Missingness Type and Evaluating the Impact of Imputation Methods on Experimental Replication
Published in Analytical chemistry (Washington) (09-08-2022)“…Missing data is a significant issue in metabolomics that is often neglected when conducting data preprocessing, particularly when it comes to imputation. This…”
Get full text
Journal Article -
12
Context Pre-Exposure Obscures Amygdala Modulation of Contextual-Fear Conditioning
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-09-2005)“…We report that post-training inactivation of basolateral amygdala region (BLA) with muscimol impaired memory for contextual-fear conditioning (as measured by…”
Get full text
Journal Article -
13
Exploring the Effect of Growth Conditions on the Volatile Metabolome of Chromobacterium vaccinii using GC×GC‐TOF‐MS
Published in The FASEB journal (01-04-2020)“…Abstract only Chromobacterium spp. have been found to grow in a variety of environments and have an extensive metabolic flexibility. Due to this flexibility,…”
Get full text
Journal Article -
14
Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus
Published in Behavioural brain research (21-08-2002)“…Prior research has revealed that treatments that elevate the level of the pro-inflammatory cytokine IL-1β in the brain, if given after training, impair…”
Get full text
Journal Article -
15
Memory for context is impaired by injecting anisomycin into dorsal hippocampus following context exploration
Published in Behavioural brain research (21-08-2002)“…Pre-exposure to the context facilitates the small amount of contextual fear conditioning that is normally produced by immediate shock. This context…”
Get full text
Journal Article -
16
5 Differences in IL1β expression in brain and periphery between young and aging rats 2h to 2 week following an ip E. coli injection
Published in Brain, behavior, and immunity (01-07-2005)Get full text
Journal Article -
17