Search Results - "Higazi, D"

N‐terminal or signal peptide sequence engineering prevents truncation of human monoclonal antibody light chains by Gibson, S. J., Bond, N. J., Milne, S., Lewis, A., Sheriff, A., Pettman, G., Pradhan, R., Higazi, D. R., Hatton, D.

“…ABSTRACT Monoclonal antibodies (mAbs) contain short N‐terminal signal peptides on each individual polypeptide that comprises the mature antibody, targeting…”
Get full text

Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple sclerosis by Morgan, L, Shah, B, Rivers, L.E, Barden, L, Groom, A.J, Chung, R, Higazi, D, Desmond, H, Smith, T, Staddon, J.M

“…Abstract Multiple sclerosis (MS) is a disease of the CNS in which inflammation, demyelination and neurodegeneration contribute to its initiation and…”
Get full text

Calcium in the heart: when it's good, it's very very good, but when it's bad, it's horrid by Roderick, H L, Higazi, D R, Smyrnias, I, Fearnley, C, Harzheim, D, Bootman, M D

“…Ca(2+) increases in the heart control both contraction and transcription. To accommodate a short-term increased cardiovascular demand, neurohormonal modulators…”
Get more information