Search Results - "Hieshima, K."

Selective down-regulation of Th2 cell-mediated airway inflammation in mice by pharmacological intervention of CCR4 by Kaminuma, O., Ohtomo, T., Mori, A., Nagakubo, D., Hieshima, K., Ohmachi, Y., Noda, Y., Katayama, K., Suzuki, K., Motoi, Y., Kitamura, N., Saeki, M., Nishimura, T., Yoshie, O., Hiroi, T.

“…Summary Background The chemokine receptor CCR4 has been implicated in Th2 cell‐mediated immune responses. However, other T cell subsets are also known to…”
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Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes by Manjunath, N, Shankar, P, Wan, J, Weninger, W, Crowley, M A, Hieshima, K, Springer, T A, Fan, X, Shen, H, Lieberman, J, von Andrian, U H

“…The lineage relationship between short-lived effector T cells and long-lived memory cells is not fully understood. We have described T-GFP mice previously, in…”
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Aberrant expression of Fra-2 promotes CCR4 expression and cell proliferation in adult T-cell leukemia by Nakayama, T, Hieshima, K, Arao, T, Jin, Z, Nagakubo, D, Shirakawa, A-K, Yamada, Y, Fujii, M, Oiso, N, Kawada, A, Nishio, K, Yoshie, O

“…Adult T-cell leukemia (ATL) is a mature CD4 + T-cell malignancy etiologically associated with human T-cell leukemia virus type 1 (HTLV-1). Primary ATL cells…”
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Cutting Edge: Profile of Chemokine Receptor Expression on Human Plasma Cells Accounts for Their Efficient Recruitment to Target Tissues by Nakayama, Takashi, Hieshima, Kunio, Izawa, Dai, Tatsumi, Youichi, Kanamaru, Akihisa, Yoshie, Osamu

“…We systematically examined the repertoire of chemokine receptors expressed by human plasma cells. Fresh bone marrow plasma cells and myeloma cells consistently…”
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CCR7 signals are essential for cortex-medulla migration of developing thymocytes by Ueno, Tomoo, Saito, Fumi, Gray, Daniel H D, Kuse, Sachiyo, Hieshima, Kunio, Nakano, Hideki, Kakiuchi, Terutaka, Lipp, Martin, Boyd, Richard L, Takahama, Yousuke

“…Upon TCR-mediated positive selection, developing thymocytes relocate within the thymus from the cortex to the medulla for further differentiation and…”
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RANKL-induced DC-STAMP is essential for osteoclastogenesis by Kukita, Toshio, Wada, Naohisa, Kukita, Akiko, Kakimoto, Takashi, Sandra, Ferry, Toh, Kazuko, Nagata, Kengo, Iijima, Tadahiko, Horiuchi, Madoka, Matsusaki, Hiromi, Hieshima, Kunio, Yoshie, Osamu, Nomiyama, Hisayuki

“…Osteoclasts are bone-resorbing, multinucleated giant cells that are essential for bone remodeling and are formed through cell fusion of mononuclear precursor…”
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Dual Functions of Fractalkine/CX3C Ligand 1 in Trafficking of Perforin+/Granzyme B+ Cytotoxic Effector Lymphocytes That Are Defined by CX3CR1 Expression by Nishimura, Miyuki, Umehara, Hisanori, Nakayama, Takashi, Yoneda, Osamu, Hieshima, Kunio, Kakizaki, Mayumi, Dohmae, Naochika, Yoshie, Osamu, Imai, Toshio

“…Fractalkine/CX3C ligand 1 and its receptor CX3CR1 are known to mediate both cell adhesion and cell migration. Here we show that CX3CR1 defines peripheral blood…”
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Characterization of cytokine LD78 gene promoters: positive and negative transcriptional factors bind to a negative regulatory element common to LD78, interleukin-3, and granulocyte-macrophage colony-stimulating factor gene promoters by NOMIYAMA, H, HIESHIMA, K, HIROKAWA, K, HATTORI, T, TAKATSUKI, K, MIURA, R

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Dopamine Selectively Induces Migration and Homing of Naive CD8+ T Cells via Dopamine Receptor D3 by Watanabe, Yoshiko, Nakayama, Takashi, Nagakubo, Daisuke, Hieshima, Kunio, Jin, Zhe, Katou, Fuminori, Hashimoto, Kenji, Yoshie, Osamu

“…The nervous systems affect immune functions by releasing neurohormones and neurotransmitters. A neurotransmitter dopamine signals via five different…”
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CC Chemokine Ligands 25 and 28 Play Essential Roles in Intestinal Extravasation of IgA Antibody-Secreting Cells by Hieshima, Kunio, Kawasaki, Yuri, Hanamoto, Hitoshi, Nakayama, Takashi, Nagakubo, Daisuke, Kanamaru, Akihisa, Yoshie, Osamu

“…CCL25 (also known as thymus-expressed chemokine) and CCL28 (also known as mucosae-associated epithelial chemokine) play important roles in mucosal immunity by…”
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Frequent expression of CCR4 in adult T-cell leukemia and human T-cell leukemia virus type 1–transformed T cells by Yoshie, Osamu, Fujisawa, Ryuichi, Nakayama, Takashi, Harasawa, Hitomi, Tago, Hideaki, Izawa, Dai, Hieshima, Kunio, Tatsumi, Youichi, Matsushima, Kouji, Hasegawa, Hitoshi, Kanamaru, Akihisa, Kamihira, Shimeru, Yamada, Yasuaki

“…Chemokines and chemokine receptors play important roles in migration and tissue localization of various lymphocyte subsets. Here, we report the highly frequent…”
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CCL28 Has Dual Roles in Mucosal Immunity as a Chemokine with Broad-Spectrum Antimicrobial Activity by Hieshima, Kunio, Ohtani, Haruo, Shibano, Michiko, Izawa, Dai, Nakayama, Takashi, Kawasaki, Yuri, Shiba, Fumio, Shiota, Mitsuru, Katou, Fuminori, Saito, Takuya, Yoshie, Osamu

“…CCL28 is a CC chemokine signaling via CCR10 and CCR3 that is selectively expressed in certain mucosal tissues such as exocrine glands, trachea, and colon…”
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Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion by Imai, T, Hieshima, K, Haskell, C, Baba, M, Nagira, M, Nishimura, M, Kakizaki, M, Takagi, S, Nomiyama, H, Schall, T J, Yoshie, O

“…Leukocyte trafficking at the endothelium requires both cellular adhesion molecules and chemotactic factors. Fractalkine, a novel transmembrane molecule with a…”
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Selective Induction of Th2-Attracting Chemokines CCL17 and CCL22 in Human B Cells by Latent Membrane Protein 1 of Epstein-Barr Virus by NAKAYAMA, Takashi, HIESHIMA, Kunio, NAGAKUBO, Daisuke, SATO, Emiko, NAKAYAMA, Masahiro, KAWA, Keisei, YOSHIE, Osamu

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Liver-Expressed Chemokine/CC Chemokine Ligand 16 Attracts Eosinophils by Interacting with Histamine H4 Receptor by Nakayama, Takashi, Kato, Yoshiko, Hieshima, Kunio, Nagakubo, Daisuke, Kunori, Yuichi, Fujisawa, Takao, Yoshie, Osamu

“…Liver-expressed chemokine (LEC)/CCL16 is a human CC chemokine that is constitutively expressed by the liver parenchymal cells and present in the normal plasma…”
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Expression of CCL28 by Reed-Sternberg Cells Defines a Major Subtype of Classical Hodgkin's Disease with Frequent Infiltration of Eosinophils and/or Plasma Cells by Hanamoto, Hitoshi, Nakayama, Takashi, Miyazato, Hajime, Takegawa, Sumio, Hieshima, Kunio, Tatsumi, Yoichi, Kanamaru, Akihisa, Yoshie, Osamu

“…Classical Hodgkin's disease (HD) is characterized by rare neoplastic Hodgkin and Reed-Sternberg (H-RS) cells within abundant reactive cellular backgrounds. In…”
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Identification of CCR6, the Specific Receptor for a Novel Lymphocyte-directed CC Chemokine LARC by Baba, M, Imai, T, Nishimura, M, Kakizaki, M, Takagi, S, Hieshima, K, Nomiyama, H, Yoshie, O

“…L iver and a ctivation- r egulated c hemokine (LARC) is a recently identified CC chemokine that is expressed mainly in the liver. LARC functions as a selective…”
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Molecular Cloning of a Novel Human CC Chemokine EBI1-ligand Chemokine That Is a Specific Functional Ligand for EBI1, CCR7 by Yoshida, R, Imai, T, Hieshima, K, Kusuda, J, Baba, M, Kitaura, M, Nishimura, M, Kakizaki, M, Nomiyama, H, Yoshie, O

“…By searching the e xpressed s equence t ag (EST) data base, we identified partial cDNA sequences encoding a novel human CC chemokine. We determined the…”
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Inducible expression of a CC chemokine liver- and activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3α/CCL20 by epidermal keratinocytes and its role in atopic dermatitis by Nakayama, Takashi, Fujisawa, Ryuichi, Yamada, Hidekazu, Horikawa, Tatsuya, Kawasaki, Hiroshi, Hieshima, Kunio, Izawa, Dai, Fujiie, Satoru, Tezuka, Tadashi, Yoshie, Osamu

“…Liverand activation-regulated chemokine (LARC)/macrophage inflammatory protein (MIP)-3α/CCL20 is a CC chemokine which is constitutively expressed by…”
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Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2 by Hieshima, K, Imai, T, Opdenakker, G, Van Damme, J, Kusuda, J, Tei, H, Sakaki, Y, Takatsuki, K, Miura, R, Yoshie, O, Nomiyama, H

“…Partial overlapping cDNA sequences likely to encode a novel human CC chemokine were identified from the GenBank Expressed Sequence Tag data base. Using these…”
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