Search Results - "Hier, Michael"
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Systemic inflammatory markers as independent prognosticators of head and neck squamous cell carcinoma
Published in Head & neck (01-01-2015)“…Background The purpose of this study was to investigate the prognostic value of the pretreatment inflammatory markers platelet‐to‐lymphocyte ratio (PLR) and…”
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Randomized Trial of Radiotherapy Versus Transoral Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma: Long-Term Results of the ORATOR Trial
Published in Journal of clinical oncology (10-03-2022)“…The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has risen rapidly, because of an epidemic of human papillomavirus infection. The optimal…”
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Loss of Independence in Older Adults With Operable Oral Cavity Cancer: A Retrospective Cohort Study
Published in Otolaryngology-head and neck surgery (01-08-2024)“…Objective To ascertain the effect of curative‐intent surgery on loss of independence (LOI) in patients with oral cavity squamous cell carcinoma (OCSCC). Study…”
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E-liquid alters oral epithelial cell function to promote epithelial to mesenchymal transition and invasiveness in preclinical oral squamous cell carcinoma
Published in Scientific reports (27-02-2023)“…The gaining popularity of tobacco and nicotine delivery products, such as electronic cigarettes (e-cigarettes) being perceived as relatively safe is of a…”
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The protective role of postoperative radiation therapy in low and intermediate grade major salivary gland malignancies: A study of the Canadian Head and Neck Collaborative Research Initiative
Published in Cancer (15-10-2023)“…The objective of this study was to examine the utility of postoperative radiation for low and intermediate grade cancers of the parotid and submandibular…”
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Application of the Milan system for reporting salivary gland cytopathology using cell blocks
Published in Virchows Archiv : an international journal of pathology (01-10-2022)“…The Milan system for reporting salivary gland cytopathology (MSRSGC) is a novel standardized classification tool for salivary gland cytology specimens based on…”
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Prioritization of head and neck cancer patient care during the COVID-19 pandemic: a retrospective cohort study
Published in Journal of otolaryngology-head and neck surgery (14-02-2023)“…The COVID-19 pandemic placed considerable strain on the healthcare system, leading to the re-allocation of resources and implementation of new practice…”
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Neoadjuvant Capecitabine in Operable HPV-Negative Head and Neck Cancer: Fortuitous Findings in a Resource Constrained Setting
Published in Otolaryngology-head and neck surgery (29-09-2024)“…Limited progress has occurred in treating operable human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC). Accessing timely care…”
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Latent Granulomatous Foreign Body Reaction to Dermal Fillers: A Case Report
Published in Ear, nose, & throat journal (23-12-2023)Get full text
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10
Therapeutic Vaccines for HPV-Associated Oropharyngeal and Cervical Cancer: The Next De-Intensification Strategy?
Published in International journal of molecular sciences (01-08-2022)“…The rise in human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) has prompted a quest for further understanding of the role of…”
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Prognostic factors of head and neck cutaneous squamous cell carcinoma: a systematic review
Published in Journal of otolaryngology-head and neck surgery (07-09-2021)“…Head and neck cutaneous squamous cell carcinoma (HNCSCC) is a non-melanoma skin cancer that is mostly caused by solar ultraviolet radiation exposure. While it…”
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BRAF V600E mutation is associated with aggressive features in papillary thyroid carcinomas ≤ 1.5 cm
Published in Journal of otolaryngology-head and neck surgery (06-11-2021)“…While some studies suggest that the BRAF V600E mutation correlates with a high-risk phenotype in papillary thyroid microcarcinoma (PTMC), more evidence is…”
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Ndrg1 Deficiency is associated with Regional Metastasis in Oral Cancer by inducing Epithelial-Mesenchymal transition
Published in Carcinogenesis (New York) (10-07-2020)“…Regional metastasis is the single most important prognostic factor in oral squamous cell carcinoma (OSCC). Abnormal expression of N-myc downstream-regulated…”
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Molecular mutations as a possible factor for determining extent of thyroid surgery
Published in Journal of otolaryngology-head and neck surgery (17-10-2019)“…Molecular testing of thyroid nodules is a diagnostic tool used to better understand the nature of thyroid nodules. The aim of this study is to better…”
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Risk Factors Associated With Reoperative Surgery for Thyroid Malignancies: A Retrospective Cohort Study
Published in Otolaryngology-head and neck surgery (01-03-2023)“…Objective To examine various factors associated with an increased risk of reoperation for persistent or recurrent malignant thyroid cancers. Study Design…”
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Aetiological heterogeneity of head and neck squamous cell carcinomas: the role of human papillomavirus infections, smoking and alcohol
Published in Carcinogenesis (New York) (07-12-2017)“…Tobacco and alcohol consumption are the main risk factors for head and neck squamous cell carcinoma (HNSCC). In addition, human papillomavirus (HPV) infection…”
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Epithelial-mesenchymal transition (EMT) markers have prognostic impact in multiple primary oral squamous cell carcinoma
Published in Clinical & experimental metastasis (01-01-2015)“…Multiple primary tumors can occur in up to 35 % of the patients with head and neck cancer, however its clinicopathological features remain controversial…”
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Quality of Life After Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharynx Cancer
Published in JAMA otolaryngology-- head & neck surgery (01-01-2024)“…Efforts are underway to deintensified treatment protocols for patients with human papillomavirus virus-associated oropharyngeal squamous cell carcinoma…”
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Effect of Having Concurrent Mutations on the Degree of Aggressiveness in Patients with Thyroid Cancer Positive for TERT Promoter Mutations
Published in Cancers (08-01-2023)“…This study aimed to examine whether concurrent mutations with a promoter mutation are associated with a greater likelihood of more aggressive disease than a…”
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Improving PEEK bioactivity for craniofacial reconstruction using a 3D printed scaffold embedded with mesenchymal stem cells
Published in Journal of biomaterials applications (01-07-2016)“…Objective Polyetheretherketone (PEEK) is a bioinert thermoplastic that has been investigated for its potential use in craniofacial reconstruction; however, its…”
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