Search Results - "Hiemstra, Annemieke"
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Consensus molecular subtype classification of colorectal adenomas
Published in The Journal of pathology (01-11-2018)“…Consensus molecular subtyping is an RNA expression‐based classification system for colorectal cancer (CRC). Genomic alterations accumulate during CRC…”
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Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study
Published in Annals of internal medicine (19-12-2017)“…The fecal immunochemical test (FIT) for detecting hemoglobin is used widely for noninvasive colorectal cancer (CRC) screening, but its sensitivity leaves room…”
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3
Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify
Published in Molecular & cellular proteomics (01-10-2017)“…Proteogenomics, i.e. comprehensive integration of genomics and proteomics data, is a powerful approach identifying novel protein biomarkers. This is especially…”
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A prognostic classifier for patients with colorectal cancer liver metastasis, based on AURKA, PTGS2 and MMP9
Published in Oncotarget (12-01-2016)“…Prognosis of patients with colorectal cancer liver metastasis (CRCLM) is estimated based on clinicopathological models. Stratifying patients based on tumor…”
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Molecular imaging of aurora kinase A (AURKA) expression: Synthesis and preclinical evaluation of radiolabeled alisertib (MLN8237)
Published in Nuclear medicine and biology (01-01-2016)“…Abstract Introduction Survival of patients after resection of colorectal cancer liver metastasis (CRCLM) is 36%–58%. Positron emission tomography (PET)…”
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Su1874 Stool Proteomics Reveals New Candidate Biomarkers for Colorectal Cancer Screening
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2012)Get full text
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Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression
Published in International journal of cancer (01-04-2020)“…Removal of colorectal adenomas is an effective strategy to reduce colorectal cancer (CRC) mortality rates. However, as only a minority of adenomas progress to…”
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Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome
Published in Critical care medicine (01-08-2007)Get full text
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Abstract 1559: Proteogenomic analysis of alternative splicing in colorectal adenoma-to-carcinoma progression
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Background Early diagnosis of colorectal cancer (CRC) and identification of its precursor lesions (adenomas) is crucial in reducing CRC mortality rates. The…”
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Prevalence of inflicted and neglectful femur shaft fractures in young children in national level I trauma centers
Published in Pediatric radiology (01-11-2022)“…Background The prevalence of inflicted femur fractures in young children varies (1.5–35.2%), but these data are based on small retrospective studies with high…”
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Abstract 848: Proteogenomic analysis of alternative splicing: the search for novel biomarkers for colorectal cancer
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Introduction Early detection of colorectal cancer (CRC) and its precursor lesions (adenomas) is crucial to reduce mortality rates. The fecal immunochemical…”
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The prevalence of non-accidental trauma among children with polytrauma: A nationwide level-I trauma centre study
Published in Journal of forensic and legal medicine (01-08-2022)“…We aimed to investigate the prevalence and characteristics of non-accidental trauma (NAT) in children with polytrauma treated at level-I trauma centres (TC)…”
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Abstract 3176: Improved colorectal cancer screening by new stool-based protein markers
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Background The fecal immunochemical test (FIT) is used in many countries for non-invasive screening for colorectal cancer (CRC), but its characteristics leave…”
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14
Body temperature and mortality in patients with acute respiratory distress syndrome
Published in American journal of critical care (01-01-2015)“…Little is known about the relationship between body temperature and outcomes in patients with acute respiratory distress syndrome (ARDS). A better…”
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Abstract 112: Synthesis and preclinical evaluation of radiolabeled alisertib as an investigational aurora kinase A PET tracer
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Background: High expression of the aurora kinase A (AURKA) protein is associated with colorectal adenoma-to-carcinoma progression and with poor prognosis of…”
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High prevalence of non-accidental trauma among deceased children presenting at Level I trauma centers in the Netherlands
Published in Forensic science, medicine, and pathology (01-12-2021)“…Purpose Between 0.1—3% of injured children who present at a hospital emergency department ultimately die as a result of their injuries. These events are…”
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Abstract 1563: Stool proteomics reveals novel candidate biomarkers for colorectal cancer screening
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Introduction and objectives: Early detection of colorectal cancer (CRC) and its precursor lesions is an effective approach to reduce CRC mortality rates. The…”
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Abstract 2853: Epidermal growth factor receptor (EGFR) and prostaglandin-endoperoxide synthase 2 (PTGS2) are prognostic biomarkers for metastatic colorectal cancer
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Background: Resection of colorectal cancer liver metastasis (CRCLM) with curative intent is beneficial in approximately 30% of cases, indicating the need for…”
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HGF signaling regulates Claudin-3 dynamics through its C-terminal tyrosine residues
Published in Tissue barriers (01-10-2013)“…The hormone HGF regulates morphogenesis and regeneration of multiple organs and increased HGF signaling is strongly associated with metastatic cancer. At the…”
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Higher Urine Nitric Oxide Is Associated with Improved Outcomes in Patients with Acute Lung Injury
Published in American journal of respiratory and critical care medicine (01-02-2007)“…Nitrogen oxide (NO) species are markers for oxidative stress that may be pathogenic in acute lung injury (ALI). We tested two hypotheses in patients with ALI:…”
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