Search Results - "Hideki Shuto"

Tumor Necrosis Factor-α Mediates the Blood–Brain Barrier Dysfunction Induced by Activated Microglia in Mouse Brain Microvascular Endothelial Cells by Nishioku, Tsuyoshi, Matsumoto, Junichi, Dohgu, Shinya, Sumi, Noriko, Miyao, Kenji, Takata, Fuyuko, Shuto, Hideki, Yamauchi, Atsushi, Kataoka, Yasufumi

“…The present study was designed to elucidate the involvement of tumor necrosis factor-α (TNF-α) release from activated microglia in the induction of blood–brain…”
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Medication use as a risk factor for inpatient falls in an acute care hospital: a case‐crossover study by Shuto, Hideki, Imakyure, Osamu, Matsumoto, Junichi, Egawa, Takashi, Jiang, Ying, Hirakawa, Masaaki, Kataoka, Yasufumi, Yanagawa, Takashi

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Benzodiazepines, antidepressants, antipsychotic agents, anti‐arrhythmic agents, opioid analgesics and…”
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Disruption of the blood–brain barrier in collagen-induced arthritic mice by Nishioku, Tsuyoshi, Yamauchi, Atsushi, Takata, Fuyuko, Watanabe, Takuya, Furusho, Koki, Shuto, Hideki, Dohgu, Shinya, Kataoka, Yasufumi

“…Patients with rheumatoid arthritis (RA) are at higher risk of developing pathological cardiovascular and cerebrovascular events than non-RA subjects. Vascular…”
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DRESS Syndrome Caused by Cross-reactivity Between Vancomycin and Subsequent Teicoplanin Administration: A Case Report by Miyazu, Daisuke, Kodama, Nobuhiro, Yamashita, Daiki, Tanaka, Hirokazu, Inoue, Sachiko, Imakyure, Osamu, Hirakawa, Masaaki, Shuto, Hideki, Kataoka, Yasufumi

“…BACKGROUND Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening syndrome comprising severe skin eruption,…”
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Cyclosporin A induces hyperpermeability of the blood–brain barrier by inhibiting autocrine adrenomedullin-mediated up-regulation of endothelial barrier function by Dohgu, Shinya, Sumi, Noriko, Nishioku, Tsuyoshi, Takata, Fuyuko, Watanabe, Takuya, Naito, Mikihiko, Shuto, Hideki, Yamauchi, Atsushi, Kataoka, Yasufumi

“…Cyclosporin A, a potent immunosuppressant, can often produce neurotoxicity in patients, although its penetration into the brain is restricted by the…”
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The statins fluvastatin and pravastatin exert anti-flushing effects by improving vasomotor dysfunction through nitric oxide-mediated mechanisms in ovariectomized animals by Shuto, Hideki, Tominaga, Koji, Yamauchi, Atsushi, Ikeda, Munehiko, Kusaba, Kenji, Mitsunaga, Daisuke, Hirabara, Yasutoshi, Egawa, Takashi, Takano, Yukio, Kataoka, Yasufumi

“…Statins have pleiotropic vascular protective effects that are independent of their cholesterol-lowering effects. The aim of the present study was to determine…”
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Autocrine and paracrine up-regulation of blood–brain barrier function by plasminogen activator inhibitor-1 by Dohgu, Shinya, Takata, Fuyuko, Matsumoto, Junichi, Oda, Masatoshi, Harada, Eriko, Watanabe, Takuya, Nishioku, Tsuyoshi, Shuto, Hideki, Yamauchi, Atsushi, Kataoka, Yasufumi

“…The blood–brain barrier (BBB) is the interface that separates the central nervous system (CNS) from the peripheral circulation. An increase in blood-borne…”
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Significance of combined cyclosporine−prednisolone therapy and cyclosporine blood concentration monitoring for idiopathic membranous nephropathy with steroid-resistant nephrotic syndrome: a randomized controlled multicenter trial by Saito, Takao, Iwano, Masayuki, Matsumoto, Koichi, Mitarai, Tetsuya, Yokoyama, Hitoshi, Yorioka, Noriaki, Nishi, Shinichi, Yoshimura, Ashio, Sato, Hiroshi, Ogahara, Satoru, Shuto, Hideki, Kataoka, Yasufumi, Ueda, Shiro, Koyama, Akio, Maruyama, Shoichi, Nangaku, Masaomi, Imai, Enyu, Matsuo, Seiichi, Tomino, Yasuhiko

“…Background Combined treatment with cyclosporine microemulsion preconcentrate (CyA MEPC) and steroids has been widely used for idiopathic membranous nephropathy…”
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Oncostatin M induces functional and structural impairment of blood–brain barriers comprised of rat brain capillary endothelial cells by Takata, Fuyuko, Sumi, Noriko, Nishioku, Tsuyoshi, Harada, Eriko, Wakigawa, Tomoya, Shuto, Hideki, Yamauchi, Atsushi, Kataoka, Yasufumi

“…Oncostatin M (OSM), a member of the interleukin-6 family, is produced by monocytes and macrophages in the peripheral blood and microglia in the brain. The…”
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Vascular dysfunction and impaired insulin signaling in high-fat diet fed ovariectomized mice by Tominaga, Koji, Yamauchi, Atsushi, Egawa, Takashi, Tanaka, Ryosuke, Kawahara, Satoko, Shuto, Hideki, Kataoka, Yasufumi

“…The metabolic syndrome, characterized by conditions such as obesity and insulin resistance, is more prevalent in postmenopausal women than in premenopausal…”
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Partial hepatectomy aggravates cyclosporin A-induced neurotoxicity by lowering the function of the blood–brain barrier in mice by Yamauchi, Atsushi, Dohgu, Shinya, Takata, Fuyuko, Watanabe, Takuya, Nishioku, Tsuyoshi, Matsumoto, Junich, Ohkubo, Yuka, Shuto, Hideki, Kataoka, Yasufumi

“…Cyclosporin A, a calcineurin inhibitor, produces neurotoxicity with relatively high frequency in organ-transplanted patients. The aim of the present study was…”
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An inhibitory role of nitric oxide in the dynamic regulation of the blood-brain barrier function by Yamauchi, Atsushi, Dohgu, Shinya, Nishioku, Tsuyoshi, Shuto, Hideki, Naito, Mikihiko, Tsuruo, Takashi, Sawada, Yasufumi, Kataoka, Yasufumi

“…1. The present study aimed at elucidating the effect of nitric oxide (NO) on blood-brain barrier (BBB) function with mouse brain capillary endothelial (MBEC4)…”
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Protective Action of Indapamide, a Thiazide-Like Diuretic, on Ischemia-Induced Injury and Barrier Dysfunction in Mouse Brain Microvascular Endothelial Cells by Nishioku, Tsuyoshi, Takata, Fuyuko, Yamauchi, Atsushi, Sumi, Noriko, Yamamoto, Ikumi, Fujino, Akiko, Naito, Mikihiko, Tsuruo, Takashi, Shuto, Hideki, Kataoka, Yasufumi

“…The aim of the present study was to elucidate the effects of indapamide on ischemic damage to the blood-brain barrier (BBB) in vitro. The ischemia /reperfusion…”
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Selective serotonin reuptake inhibitors fluvoxamine and paroxetine restore forced exercise-induced temperature dysregulation in ovariectomized mice by Ikeda, Munehiko, Egawa, Takashi, Yamauchi, Atsushi, Sohda, Yoshio, Koga, Ayako, Tominaga, Kohji, Shuto, Hideki, Kataoka, Yasufumi

“…Hot flushes are one of the most frequent symptoms in menopausal women. Selective serotonin reuptake inhibitors (SSRIs) are considered to be first-line therapy…”
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Inhibition of transforming growth factor-beta production in brain pericytes contributes to cyclosporin A-induced dysfunction of the blood-brain barrier by Takata, Fuyuko, Dohgu, Shinya, Yamauchi, Atsushi, Sumi, Noriko, Nakagawa, Shinsuke, Naito, Mikihiko, Tsuruo, Takashi, Shuto, Hideki, Kataoka, Yasufumi

“…: 1. The present study was designed to clarify whether brain pericytes and pericyte-derived transforming growth factor-beta1 (TGF-beta1) participate in…”
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Adverse effect of cyclosporin A on barrier functions of cerebral microvascular endothelial cells after hypoxia-reoxygenation damage in vitro by Dohgu, Shinya, Nishioku, Tsuyoshi, Sumi, Noriko, Takata, Fuyuko, Nakagawa, Shinsuke, Naito, Mikihiko, Tsuruo, Takashi, Yamauchi, Atsushi, Shuto, Hideki, Kataoka, Yasufumi

“…Hypoxia and post-hypoxic reoxygenation induces disruption of the blood-brain barrier (BBB). Alterations of the BBB function after hypoxia/reoxygenation (H/R)…”
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P1J-8-4 A correlation between tail-skin temperature induced by forced exercise and metabolic parameters in ovariectomized mice fed high-fat diet by Satoko Kawahara, Ryousuke Tanaka, Kouji Tominaga, Hideki Shuto, Yasufumi Kataoka

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Forced Exercise-Induced Flushing of Tail Skin in Ovariectomized Mice, as a New Experimental Model of Menopausal Hot Flushes by Shuto, Hideki, Yamauchi, Atsushi, Ikeda, Munehiko, Sohda, Yoshio, Koga, Ayako, Tominaga, Kohji, Egawa, Takashi, Kataoka, Yasufumi

“…Hot flushes are the most common complaint of menopausal women. In the present study, a new animal model of hot flushes was established. Tail skin temperature…”
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P2-18-3 Estrogen deficiency impairs sensitivity of the baroreceptor reflex (baroreflex) and vasomotor functions in the aorta by Yasutoshi Hirabara, Sayo Tumura, Sayaka Morimoto, Yuuya Hirata, Tomohiro Ogasawara, Kenji Honda, Ryo Saito, Hideki Shuto, Yasufumi Kataoka, Yukio Takano

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P1J6-10 Effect of olanzapine on lipid metabolisms mediated by AMPK-SREBP signaling in the hepatocytes (HepG2 cells) by Sayako Eguchi, Hirotomo Uematsu, Ei Sejima, Yu Oshima, Hideki Shuto, Atsushi Yamauchi, Yasufumi Kataoka

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