Search Results - "Hideki Aizaki"

Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization by Iwamoto, Masashi, Saso, Wakana, Sugiyama, Ryuichi, Ishii, Koji, Ohki, Mio, Nagamori, Shushi, Suzuki, Ryosuke, Aizaki, Hideki, Ryo, Akihide, Yun, Ji-Hye, Park, Sam-Yong, Ohtani, Naoko, Muramatsu, Masamichi, Iwami, Shingo, Tanaka, Yasuhito, Sureau, Camille, Wakita, Takaji, Watashi, Koichi

“…Sodium taurocholate cotransporting polypeptide (NTCP) is a host cell receptor required for hepatitis B virus (HBV) entry. However, the susceptibility of…”
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Evaluation and identification of hepatitis B virus entry inhibitors using HepG2 cells overexpressing a membrane transporter NTCP by Iwamoto, Masashi, Watashi, Koichi, Tsukuda, Senko, Aly, Hussein Hassan, Fukasawa, Masayoshi, Fujimoto, Akira, Suzuki, Ryosuke, Aizaki, Hideki, Ito, Takayoshi, Koiwai, Osamu, Kusuhara, Hiroyuki, Wakita, Takaji

“…•A new HBV-susceptible cell line, designated HepG2-hNTCP-C4, was established.•Pretreatment with 3% DMSO facilitated HBV infection into HepG2-hNTCP-C4…”
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The machinery for endocytosis of epidermal growth factor receptor coordinates the transport of incoming hepatitis B virus to the endosomal network by Iwamoto, Masashi, Saso, Wakana, Nishioka, Kazane, Ohashi, Hirofumi, Sugiyama, Ryuichi, Ryo, Akihide, Ohki, Mio, Yun, Ji-Hye, Park, Sam-Yong, Ohshima, Takayuki, Suzuki, Ryosuke, Aizaki, Hideki, Muramatsu, Masamichi, Matano, Tetsuro, Iwami, Shingo, Sureau, Camille, Wakita, Takaji, Watashi, Koichi

“…Sodium taurocholate cotransporting polypeptide (NTCP) is expressed at the surface of human hepatocytes and functions as an entry receptor of hepatitis B virus…”
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The aryl hydrocarbon receptor–cytochrome P450 1A1 pathway controls lipid accumulation and enhances the permissiveness for hepatitis C virus assembly by Ohashi, Hirofumi, Nishioka, Kazane, Nakajima, Syo, Kim, Sulyi, Suzuki, Ryosuke, Aizaki, Hideki, Fukasawa, Masayoshi, Kamisuki, Shinji, Sugawara, Fumio, Ohtani, Naoko, Muramatsu, Masamichi, Wakita, Takaji, Watashi, Koichi

“…Viruses hijack and modify host cell functions to maximize viral proliferation. Hepatitis C virus (HCV) reorganizes host cell metabolism to produce specialized…”
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NTCP Oligomerization Occurs Downstream of the NTCP-EGFR Interaction during Hepatitis B Virus Internalization by Fukano, Kento, Oshima, Mizuki, Tsukuda, Senko, Aizaki, Hideki, Ohki, Mio, Park, Sam-Yong, Wakita, Takaji, Wakae, Kousho, Watashi, Koichi, Muramatsu, Masamichi

“…Sodium taurocholate cotransporting polypeptide (NTCP) is a receptor that is essential for hepatitis B virus (HBV) entry into the host cell. A number of HBV…”
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Visualization and measurement of ATP levels in living cells replicating hepatitis C virus genome RNA by Ando, Tomomi, Imamura, Hiromi, Suzuki, Ryosuke, Aizaki, Hideki, Watanabe, Toshiki, Wakita, Takaji, Suzuki, Tetsuro

“…Adenosine 5'-triphosphate (ATP) is the primary energy currency of all living organisms and participates in a variety of cellular processes. Although ATP…”
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Sphingomyelin Is Essential for the Structure and Function of the Double-Membrane Vesicles in Hepatitis C Virus RNA Replication Factories by Gewaid, Hossam, Aoyagi, Haruyo, Arita, Minetaro, Watashi, Koichi, Suzuki, Ryosuke, Sakai, Shota, Kumagai, Keigo, Yamaji, Toshiyuki, Fukasawa, Masayoshi, Kato, Fumihiro, Hishiki, Takayuki, Mimata, Ayako, Sakamaki, Yuriko, Ichinose, Shizuko, Hanada, Kentaro, Muramatsu, Masamichi, Wakita, Takaji, Aizaki, Hideki

“…Some plus-stranded RNA viruses generate double-membrane vesicles (DMVs), one type of the membrane replication factories, as replication sites. Little is known…”
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High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon by Matsuda, Mami, Yamanaka, Atsushi, Yato, Keigo, Yoshii, Kentaro, Watashi, Koichi, Aizaki, Hideki, Konishi, Eiji, Takasaki, Tomohiko, Kato, Takanobu, Muramatsu, Masamichi, Wakita, Takaji, Suzuki, Ryosuke

“…Diseases caused by the genus Flavivirus , including dengue virus (DENV) and Zika virus (ZIKV), have a serious impact on public health worldwide. Due to…”
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Interaction of Hepatitis C Virus Nonstructural Protein 5A with Core Protein Is Critical for the Production of Infectious Virus Particles by MASAKI, Takahiro, SUZUKI, Ryosuke, SUZUKI, Tetsuro, MURAKAMI, Kyoko, AIZAKI, Hideki, ISHII, Koji, MURAYAMA, Asako, DATE, Tomoko, MATSUURA, Yoshiharu, MIYAMURA, Tatsuo, WAKITA, Takaji

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Antiviral activity of glycyrrhizin against hepatitis C virus in vitro by Matsumoto, Yoshihiro, Matsuura, Tomokazu, Aoyagi, Haruyo, Matsuda, Mami, Hmwe, Su Su, Date, Tomoko, Watanabe, Noriyuki, Watashi, Koichi, Suzuki, Ryosuke, Ichinose, Shizuko, Wake, Kenjiro, Suzuki, Tetsuro, Miyamura, Tatsuo, Wakita, Takaji, Aizaki, Hideki

“…Glycyrrhizin (GL) has been used in Japan to treat patients with chronic viral hepatitis, as an anti-inflammatory drug to reduce serum alanine aminotransferase…”
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Induction of neutralizing antibodies against hepatitis C virus by a subviral particle-based DNA vaccine by Yato, Keigo, Matsuda, Mami, Watanabe, Noriyuki, Watashi, Koichi, Aizaki, Hideki, Kato, Takanobu, Tamura, Koji, Wakita, Takaji, Muramatsu, Masamichi, Suzuki, Ryosuke

“…Direct-acting antivirals (DAAs) have been introduced for the treatment of hepatitis C virus (HCV); however, there is still no available vaccine for preventing…”
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A Novel Tricyclic Polyketide, Vanitaracin A, Specifically Inhibits the Entry of Hepatitis B and D Viruses by Targeting Sodium Taurocholate Cotransporting Polypeptide by Kaneko, Manabu, Watashi, Koichi, Kamisuki, Shinji, Matsunaga, Hiroki, Iwamoto, Masashi, Kawai, Fumihiro, Ohashi, Hirofumi, Tsukuda, Senko, Shimura, Satomi, Suzuki, Ryosuke, Aizaki, Hideki, Sugiyama, Masaya, Park, Sam-Yong, Ito, Takayoshi, Ohtani, Naoko, Sugawara, Fumio, Tanaka, Yasuhito, Mizokami, Masashi, Sureau, Camille, Wakita, Takaji

“…Anti-hepatitis B virus (HBV) drugs are currently limited to nucleos(t)ide analogs (NAs) and interferons. A challenge of drug development is the identification…”
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A Single Adaptive Mutation in Sodium Taurocholate Cotransporting Polypeptide Induced by Hepadnaviruses Determines Virus Species Specificity by Takeuchi, Junko S, Fukano, Kento, Iwamoto, Masashi, Tsukuda, Senko, Suzuki, Ryosuke, Aizaki, Hideki, Muramatsu, Masamichi, Wakita, Takaji, Sureau, Camille, Watashi, Koichi

“…Hepatitis B virus (HBV) and its hepadnavirus relatives infect a wide range of vertebrates, from fish to human. Hepadnaviruses and their hosts have a long…”
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Surfeit 4 Contributes to the Replication of Hepatitis C Virus Using Double-Membrane Vesicles by Kong, Lingbao, Aoyagi, Haruyo, Yang, Zibing, Ouyang, Tao, Matsuda, Mami, Fujimoto, Akira, Watashi, Koichi, Suzuki, Ryosuke, Arita, Minetaro, Yamagoe, Satoshi, Dohmae, Naoshi, Suzuki, Takehiro, Suzuki, Tetsuro, Muramatsu, Masamichi, Wakita, Takaji, Aizaki, Hideki

“…A number of positive-strand RNA viruses, such as hepatitis C virus (HCV) and poliovirus, use double-membrane vesicles (DMVs) as replication sites. However, the…”
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Development and Use of a Kinetical and Real-Time Monitoring System to Analyze the Replication of Hepatitis C Virus by Li, Xiaoyu, Ito, Masahiko, Aoyagi, Haruyo, Murayama, Asako, Aizaki, Hideki, Fukasawa, Masayoshi, Kato, Takanobu, Wakita, Takaji, Suzuki, Tetsuro

“…In microbiological research, it is important to understand the time course of each step in a pathogen’s lifecycle and changes in the host cell environment…”
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MCPIP1 reduces HBV-RNA by targeting its epsilon structure by Li, Yingfang, Que, Lusheng, Fukano, Kento, Koura, Miki, Kitamura, Kouichi, Zheng, Xin, Kato, Takanobu, Aly, Hussein Hassan, Watashi, Koichi, Tsukuda, Senko, Aizaki, Hideki, Watanabe, Noriyuki, Sato, Yuko, Suzuki, Tadaki, Suzuki, Hiroshi I., Hosomichi, Kazuyoshi, Kurachi, Makoto, Wakae, Kousho, Muramatsu, Masamichi

“…Hepatitis B virus (HBV) is the major causative factor of chronic viral hepatitis, liver cirrhosis, and hepatocellular carcinoma. We previously demonstrated…”
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Identification of Two Critical Neutralizing Epitopes in the Receptor Binding Domain of Hepatitis B Virus preS1 by Yato, Keigo, Onodera, Taishi, Matsuda, Mami, Moriyama, Saya, Fujimoto, Akira, Watashi, Koichi, Aizaki, Hideki, Tanaka, Tomohisa, Moriishi, Kohji, Nishitsuji, Hironori, Shimotohno, Kunitada, Tamura, Koji, Takahashi, Yoshimasa, Wakita, Takaji, Muramatsu, Masamichi, Kato, Takanobu, Suzuki, Ryosuke

“…Hepatitis B virus (HBV) infection is a major public health problem. Human hepatocytes are infected with HBV via binding between the preS1 region in the large…”
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Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase by Suzuki, Ryosuke, Matsuda, Mami, Shimoike, Takashi, Watashi, Koichi, Aizaki, Hideki, Kato, Takanobu, Suzuki, Tetsuro, Muramatsu, Masamichi, Wakita, Takaji

“…Hepatitis C virus (HCV) was shown to activate protein kinase R (PKR), which inhibits expression of interferon (IFN) and IFN-stimulated genes by controlling the…”
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Dysregulation of Retinoic Acid Receptor Diminishes Hepatocyte Permissiveness to Hepatitis B Virus Infection through Modulation of Sodium Taurocholate Cotransporting Polypeptide (NTCP) Expression by Tsukuda, Senko, Watashi, Koichi, Iwamoto, Masashi, Suzuki, Ryosuke, Aizaki, Hideki, Okada, Maiko, Sugiyama, Masaya, Kojima, Soichi, Tanaka, Yasuhito, Mizokami, Masashi, Li, Jisu, Tong, Shuping, Wakita, Takaji

“…Sodium taurocholate cotransporting polypeptide (NTCP) is an entry receptor for hepatitis B virus (HBV) and is regarded as one of the determinants that confer…”
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Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2 by Suzuki, Ryosuke, Matsuda, Mami, Watashi, Koichi, Aizaki, Hideki, Matsuura, Yoshiharu, Wakita, Takaji, Suzuki, Tetsuro

“…Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is a hydrophobic, transmembrane protein that is required not only for NS2-NS3 cleavage, but also for…”
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