Search Results - "Hidalgo, Maria A"

Long Chain Fatty Acids as Modulators of Immune Cells Function: Contribution of FFA1 and FFA4 Receptors by Hidalgo, Maria A., Carretta, Maria D., Burgos, Rafael A.

“…Long-chain fatty acids are molecules that act as metabolic intermediates and constituents of membranes; however, their novel role as signaling molecules in…”
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Eimeria bovis-triggered neutrophil extracellular trap formation is CD11b-, ERK 1/2-, p38 MAP kinase- and SOCE-dependent by Muñoz-Caro, Tamara, Mena Huertas, Sandra Jaqueline, Conejeros, Ivan, Alarcón, Pablo, Hidalgo, María A, Burgos, Rafael A, Hermosilla, Carlos, Taubert, Anja

“…Eimeria bovis is an important coccidian parasite that causes high economic losses in the cattle industry. We recently showed that polymorphonuclear neutrophils…”
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Bovine tumor necrosis factor-alpha Increases IL-6, IL-8, and PGE2 in bovine fibroblast-like synoviocytes by metabolic reprogramming by Manosalva, Carolina, Alarcon, Pablo, Quiroga, John, Teuber, Stefanie, Carretta, Maria D., Bustamante, Hedie, Lopez-Muñoz, Rodrigo, Hidalgo, Maria A., Burgos, Rafael A.

“…Lameness is a common condition in dairy cattle caused by infectious or noninfectious agents. Joint lesions are the second most common cause of lameness and can…”
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Far beyond Phagocytosis: Phagocyte-Derived Extracellular Traps Act Efficiently against Protozoan Parasites In Vitro and In Vivo by Taubert, Anja, Hidalgo, María A., Burgos, Rafael A., Muñoz-Caro, Tamara, Silva, Liliana M. R., Hermosilla, Carlos

“…Professional mononuclear phagocytes such as polymorphonuclear neutrophils (PMN), monocytes, and macrophages are considered as the first line of defence against…”
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β-hydroxybutyrate and hydroxycarboxylic acid receptor 2 agonists activate the AKT, ERK and AMPK pathways, which are involved in bovine neutrophil chemotaxis by Carretta, María D., Barría, Yonathan, Borquez, Katherine, Urra, Bárbara, Rivera, Andrés, Alarcón, Pablo, Hidalgo, María A., Burgos, Rafael A.

“…Elevated plasma concentrations of the ketone body β-hydroxybutyrate (BHB), an endogenous agonist of the hydroxycarboxylic acid receptor 2 (HCA2), is associated…”
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ATP Induces Interleukin-8, Intracellular Calcium Release, and ERK1/2 Phosphorylation in Bovine Endometrial Cells, Partially through P2Y Receptors by Gutierrez, Noemí, Teuber, Stefanie, Alarcon, Pablo, Burgos, Rafael A, Hidalgo, María A

“…The bovine endometrium has an important defensive role in the postpartum period that acts when an inflammatory process associated with tissue damage or…”
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Free Fatty Acid Receptor 1 Signaling Contributes to Migration, MMP-9 Activity, and Expression of IL-8 Induced by Linoleic Acid in HaCaT Cells by Manosalva, Carolina, Alarcón, Pablo, González, Karina, Soto, Jorge, Igor, Karin, Peña, Fernanda, Medina, Gustavo, Burgos, Rafael A, Hidalgo, María A

“…Keratinocytes and neutrophils are the main cellular components in wound healing during re-epithelization and inflammation. Free fatty acids such as linoleic…”
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Delphinidin Reduces Glucose Uptake in Mice Jejunal Tissue and Human Intestinal Cells Lines through FFA1/GPR40 by Hidalgo, Jorge, Teuber, Stefanie, Morera, Francisco J, Ojeda, Camila, Flores, Carlos A, Hidalgo, María A, Núñez, Lucía, Villalobos, Carlos, Burgos, Rafael A

“…Anthocyanins are pigments with antihyperglycemic properties, and they are potential candidates for developing functional foods for the therapy or prevention of…”
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fMLP-Induced IL-8 Release Is Dependent on NADPH Oxidase in Human Neutrophils by Burgos, Rafael A., Cárcamo, Leonardo, Zárate, Cristian, Teuber, Stefanie E., Carretta, María D., Hidalgo, María A., Concha, Ilona I.

“…N-Formyl-methionyl-leucyl-phenylalanine (fMLP) and platelet-activating factor (PAF) induce similar intracellular signalling profiles; but only fMLP induces…”
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Cloning, identification and functional characterization of bovine free fatty acid receptor-1 (FFAR1/GPR40) in neutrophils by Manosalva, Carolina, Mena, Jaqueline, Velasquez, Zahady, Colenso, Charlotte K, Brauchi, Sebastian, Burgos, Rafael A, Hidalgo, Maria A

“…Long chain fatty acids (LCFAs), which are ligands for the G-protein coupled receptor FFAR1 (GPR40), are increased in cow plasma after parturition, a period in…”
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Indirect Measurement of CRAC Channel Activity Using NFAT Nuclear Translocation by Flow Cytometry in Jurkat Cells by Carretta, María D, Hidalgo, María A, Burgos, Rafael A

“…Flow cytometry is a powerful technology to assess the presence of NFAT in the nuclei after CRAC channel activation. Here we described a simplified procedure…”
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Differential intracellular calcium influx, nitric oxide production, ICAM-1 and IL8 expression in primary bovine endothelial cells exposed to nonesterified fatty acids by Loaiza, Anitsi, Carretta, María D, Taubert, Anja, Hermosilla, Carlos, Hidalgo, María A, Burgos, Rafael A

“…Nonesterified fatty acids (NEFAs) are involved in proinflammatory processes in cattle, including in the increased expression of adhesion molecules in…”
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Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation by Carretta, María D., Alarcón, Pablo, Jara, Evelyn, Solis, Loreto, Hancke, Juan L., Concha, Ilona I., Hidalgo, María A., Burgos, Rafael A.

“…The nuclear factor of activated T cells (NFAT) is a transcription factor essential for cytokine production during T-cell activation and is the target of…”
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Delphinidin Activates NFAT and Induces IL-2 Production Through SOCE in T Cells by Jara, Evelyn, Hidalgo, María A., Hancke, Juan L., Hidalgo, Alejandra I., Brauchi, Sebastian, Nuñez, Luisa, Villalobos, Carlos, Burgos, Rafael A.

“…Delphinidin is an anthocyanidin that possesses antioxidant and anti-inflammatory effects; however, some reports suggest that delphinidin has pro-inflammatory…”
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Metabolic disturbances in synovial fluid are involved in the onset of synovitis in heifers with acute ruminal acidosis by Alarcon, Pablo, Hidalgo, Alejandra I., Manosalva, Carolina, Cristi, Raul, Teuber, Stefanie, Hidalgo, Maria A., Burgos, Rafael A.

“…Acute ruminal acidosis (ARA) is the result of increased intake of highly fermentable carbohydrates, which frequently occurs in dairy cattle and is associated…”
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Docosahexaenoic acid and TUG-891 activate free fatty acid-4 receptor in bovine neutrophils by Olmo, Ivan, Teuber, Stefanie, Larrazabal, Camilo, Alarcon, Pablo, Raipane, Fernanda, Burgos, Rafael A., Hidalgo, Maria A.

“…•Neutrophils express the free fatty acids (FFA) 4 receptor, which is activated by docosahexaenoic acid (DHA) and TUG-891.•DHA and TUG-891 increased matrix…”
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d(-) Lactic Acid-Induced Adhesion of Bovine Neutrophils onto Endothelial Cells Is Dependent on Neutrophils Extracellular Traps Formation and CD11b Expression by Alarcón, Pablo, Manosalva, Carolina, Conejeros, Ivan, Carretta, María D, Muñoz-Caro, Tamara, Silva, Liliana M R, Taubert, Anja, Hermosilla, Carlos, Hidalgo, María A, Burgos, Rafael A

“…Bovine ruminal acidosis is of economic importance as it contributes to reduced milk and meat production. This phenomenon is mainly attributed to an overload of…”
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Differential free fatty acid receptor-1 (FFAR1/GPR40) signalling is associated with gene expression or gelatinase granule release in bovine neutrophils by Mena, Sandra J, Manosalva, Carolina, Carretta, Maria D, Teuber, Stefanie, Olmo, Iván, Burgos, Rafael A, Hidalgo, Maria A

“…Fatty acids have been recognized as regulators of immune function in addition to their known metabolic role. Long-chain fatty acids bind free fatty acid…”
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Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps via Pannexin 1-Dependent ATP Release and P2X1 Receptor Activation by Alarcón, Pablo, Manosalva, Carolina, Quiroga, John, Belmar, Isidora, Álvarez, Karina, Díaz, Gustavo, Taubert, Anja, Hermosilla, Carlos, Carretta, María D., Burgos, Rafael A., Hidalgo, María A.

“…Non-esterified fatty acids (NEFAs) such as oleic acid (OA) and linoleic acid (LA) are associated with a higher incidence of infectious diseases such as…”
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Oleic acid induces intracellular calcium mobilization, MAPK phosphorylation, superoxide production and granule release in bovine neutrophils by Hidalgo, Maria A., Nahuelpan, Carla, Manosalva, Carolina, Jara, Evelyn, Carretta, Maria D., Conejeros, Ivan, Loaiza, Anitsi, Chihuailaf, Ricardo, Burgos, Rafael A.

“…► Presence of a bovine ortholog GPR40 receptor in bovine neutrophils. ► Oleic acid and the selective agonist of GPR40 GW9508 activate second messenger. ► Oleic…”
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