Search Results - "Hidaka, Shuji"

Two cases of conventional fulminant type 1 diabetes: following the depletion process of endogenous insulin secretion and literature review by Iwamoto, Takamasa, Hidaka, Shuji, Sada, Kentaro, Shibata, Hirotaka

“…Fulminant type 1 diabetes (FT1D) is a rapidly progressive form of diabetes in which the endogenous capacity to secrete insulin is depleted. The onset is…”
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Glycemic variability is associated with sural nerve conduction velocity in outpatients with type 2 diabetes: Usefulness of a new point‐of‐care device for nerve conduction studies by Morita, Machiko, Sada, Kentaro, Hidaka, Shuji, Ogawa, Miki, Shibata, Hirotaka

“…ABSTRACT Aims/Introduction Although several studies have shown the association between continuous glucose monitoring (CGM)‐derived glycemic variability (GV)…”
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Renoprotective effect of additional sodium–glucose cotransporter 2 inhibitor therapy in type 2 diabetes patients with rapid decline and preserved renal function by Sada, Kentaro, Hidaka, Shuji, Kashima, Jin, Morita, Machiko, Sada, Kokoro, Shibata, Hirotaka

“…Aims/Introduction The slope of estimated glomerular filtration rate (eGFR) decline (eGFR slope) in early‐stage type 2 diabetes patients might predict the…”
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A case of polyneuropathy associated with diabetic ketoacidosis in new‐onset type 1 diabetes by Sada, Kokoro, Hidaka, Shuji, Takemaru, Makoto, Ueno, Daisuke, Shibata, Hirotaka

“…ABSTRACT Although diabetic peripheral neuropathy is the most common diabetic microangiopathic complication, several other neuropathy syndromes can occur in the…”
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Clinical and genetic analysis in a family with familial renal glucosuria: Identification of an N101K mutation in the sodium–glucose cotransporter 2 encoded by a solute carrier family 5 member 2 gene by Sada, Kentaro, Hidaka, Shuji, Imaishi, Nao, Shibata, Kohei, Katashima, Rumi, Noso, Shinsuke, Ikegami, Hiroshi, Kakuma, Tetsuya, Shibata, Hirotaka

“…We report the identification of a mutation in the solute carrier family 5 member 2 (SLC5A2) gene, which encodes sodium–glucose cotransporter 2, in a family…”
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Skeletal Muscle AMP-Activated Protein Kinase Phosphorylation Parallels Metabolic Phenotype in Leptin Transgenic Mice Under Dietary Modification by Tanaka, Tomohiro, Hidaka, Shuji, Masuzaki, Hiroaki, Yasue, Shintaro, Minokoshi, Yasuhiko, Ebihara, Ken, Chusho, Hideki, Ogawa, Yoshihiro, Toyoda, Taro, Sato, Kenji, Miyanaga, Fumiko, Fujimoto, Muneya, Tomita, Tsutomu, Kusakabe, Toru, Kobayashi, Nozomi, Tanioka, Hideki, Hayashi, Tatsuya, Hosoda, Kiminori, Yoshimatsu, Hironobu, Sakata, Toshiie, Nakao, Kazuwa

“…Skeletal Muscle AMP-Activated Protein Kinase Phosphorylation Parallels Metabolic Phenotype in Leptin Transgenic Mice Under Dietary Modification Tomohiro Tanaka…”
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Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin‐induced diabetic rats by Hidaka, Shuji, Yoshimatsu, Hironobu, Kondou, Seiya, Tsuruta, Yoshio, Oka, Kyoko, Noguchi, Hitoshi, Okamoto, Kenjirou, Sakino, Hiroshi, Teshima, Yasushi, Okeda, Toshimitsu, Sakata, Toshiie

“…ABSTRACT We examined the effects of chronic centrally administered leptin on the glucose metabolism of streptozotocin‐induced diabetic (STZ‐D) rats, a model…”
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Analysis of the Components of Porcine Liver Hydrolysate and Examination of the Antioxidant Activity and Angiotensin Converting Enzyme (ACE)-inhibiting Activity by Inoue, Naonori, Hamasaki, Atsuko, Hidaka, Shuji, Miura, Naoyoshi, Fukahori, Masahiro, Maruyama, Masugi, Kawahara, Satoshi, Ohta, Kazuyoshi, Muguruma, Michio

“…Hypertension and oxidant stress predispose to the onset and progression of arteriosclerotic diseases. In this study, the components of two kinds of porcine…”
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Diminished Expression of Sarcoplasmic Reticulum Ca2+-ATPase and Ryanodine Sensitive Ca2+Channel mRNA in Streptozotocin-induced Diabetic Rat Heart by Teshima, Yasushi, Takahashi, Naohiko, Saikawa, Tetsunori, Hara, Masahide, Yasunaga, Seikoh, Hidaka, Shuji, Sakata, Toshiie

“…Y. Teshima, N. Takahashi, T. Saikawa, M. Hara, S. Yasunaga, S. Hidaka and T. Sakata. Diminished Expression of Sarcoplasmic Reticulum Ca2+-ATPase and Ryanodine…”
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Prevention and reversal of renal injury by leptin in a new mouse model of diabetic nephropathy by Suganami, Takayoshi, Mukoyama, Masashi, Mori, Kiyoshi, Yokoi, Hideki, Koshikawa, Masao, Sawai, Kazutomo, Hidaka, Shuji, Ebihara, Ken, Tanaka, Tomohiro, Sugawara, Akira, Kawachi, Hiroshi, Vinson, Charles, Ogawa, Yoshihiro, Nakao, Kazuwa

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メタボリックシンドロームモデルラット（SHR/NDmcr-cp）における肝臓水解物の血糖に及ぼす影響 by 井上, 尚典, 日高, 修二, 三浦, 直良, 山田, 耕太郎, 深堀, 勝博, 丸山, 眞杉, 河原, 聡, 太田, 一良, 六車, 三治男

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メタボリックシンドロームモデルラット(SHR/NDmcr-cp)における肝臓水解物の血糖に及ぼす影響 by 井上尚典, 日高修二, 三浦直良, 山田耕太郎, 深堀勝博, 丸山眞杉, 河原聡, 太田一良, 六車三治男

“…「緒言」生活様式の欧米化に伴い, 高血圧, 糖尿病, 脂質異常症等の生活習慣病が大きな社会問題となっている. 厚生労働省による平成19年の国民健康・栄養調査1)によれば, 「糖尿病が強く疑われる人」及び「糖尿病の可能性が否定できない人」の推計は約2210万人とわが国の総人口の約17.5%を占めており,…”
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ブタ肝臓水解物の成分分析と抗酸化活性及びアンギオテンシン変換酵素(ACE)阻害活性の検討 by 井上尚典, 浜崎敦子, 日高修二, 三浦直良, 深堀勝博, 丸山眞杉, 河原聡, 太田一良, 六車三治男

“…「緒言」今日社会環境とライフスタイルの著しい変化により飽食化が進み, 高血圧, 糖尿病, 脂質異常症等の生活習慣病が大きな社会問題となっている. 厚生労働省による平成22年の人口動態調査1)によれば, 日本における三大死因は, 悪性新生物, 心疾患, 脳血管疾患である. この三大死因のうち心疾患,…”
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Molecular cloning of rat uncoupling protein 2 cDNA and its expression in genetically obese Zucker fatty (fa/fa) rats by Hidaka, Shuji, Kakuma, Tetsuya, Yoshimatsu, Hironobu, Yasunaga, Seikoh, Kurokawa, Mamoru, Sakata, Toshiie

“…We isolated rat UCP2 cDNA, which has been proposed to play an important role in mammalian thermogenesis and body weight regulation. The nucleotide sequence of…”
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Effects of Liver Hydrolysate on the Blood Glucose in Metabolic Syndrome Model Rats (SHR/NDmcr-cp) by Inoue, Naonori, Hidaka, Shuji, Miura, Naoyoshi, Yamada, Kotaro, Fukahori, Masahiro, Maruyama, Masugi, Kawahara, Satoshi, Ohta, Kazuyoshi, Muguruma, Michio

“…Insulin resistance associated with visceral fat obesity has been suggested to be the pathological basis of metabolic syndrome. Many studies have demonstrated…”
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Acute central infusion of leptin modulates fatty acid mobilization by affecting lipolysis and mRNA expression for uncoupling proteins by Tajima, Daisuke, Masaki, Takayuki, Hidaka, Shuji, Kakuma, Tetsuya, Sakata, Toshiie, Yoshimatsu, Hironobu

“…Chronic administration of leptin has been shown to reduce adiposity through energy intake and expenditure. The present study aims to examine how acute central…”
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Prevention and reversal of renal injury by leptin in a new mouse model of diabetic nephropathy by Suganami, Takayoshi, Mukoyama, Masashi, Mori, Kiyoshi, Yokoi, Hideki, Koshikawa, Masao, Sawai, Kazutomo, Hidaka, Shuji, Ebihara, Ken, Tanaka, Tomohiro, Sugawara, Akira, Kawachi, Hiroshi, Vinson, Charles, Ogawa, Yoshihiro, Nakao, Kazuwa

“…ABSTRACT Diabetic nephropathy is the leading cause of end‐stage renal disease, for which effective therapy to prevent the progression at advanced stages…”
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Diminished expression of sarcoplasmic reticulum Ca(2+)-ATPase and ryanodine sensitive Ca(2+)Channel mRNA in streptozotocin-induced diabetic rat heart by Teshima, Y, Takahashi, N, Saikawa, T, Hara, M, Yasunaga, S, Hidaka, S, Sakata, T

“…The diabetic heart has an abnormal intracellular calcium ([Ca(2+)]i) metabolism. However, the responsible molecular mechanisms are unclear. The present study…”
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Enhanced expression of uncoupling protein 2 gene in rat white adipose tissue and skeletal muscle following chronic treatment with thyroid hormone by Masaki, Takayuki, Yoshimatsu, Hironobu, Kakuma, Tetsuya, Hidaka, Shuji, Kurokawa, Mamoru, Sakata, Toshiie

“…Evidence is rapidly emerging which suggests that uncoupling protein 2 (UCP2), by virtue of its ubiquitous expression, may be important for determining basal…”
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Hypothalamic neuronal histamine as a target of leptin in feeding behavior by YOSHIMATSU, H, ITATEYAMA, E, KONDOU, S, TAJIMA, D, HIMENO, K, HIDAKA, S, KUROKAWA, M, SAKATA, T

“…Hypothalamic neuronal histamine as a target of leptin in feeding behavior. H Yoshimatsu , E Itateyama , S Kondou , D Tajima , K Himeno , S Hidaka , M Kurokawa…”
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