Search Results - "Hicks, Susan C."
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Non-invasive prenatal chromosomal aneuploidy testing--clinical experience: 100,000 clinical samples
Published in PloS one (07-10-2014)“…As the first laboratory to offer massively parallel sequencing-based noninvasive prenatal testing (NIPT) for fetal aneuploidies, Sequenom Laboratories has been…”
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Proof-of-concept evaluation of next-generation sequencing-based liquid biopsy for non-invasive cancer detection in cats
Published in Frontiers in veterinary science (13-09-2024)“…This proof-of-concept evaluation demonstrates that next-generation sequencing-based liquid biopsy can detect genomic alterations in the blood of cats with…”
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Detection of Age-Related Somatic Alterations in Canine Blood Using Next-Generation Sequencing-Based Liquid Biopsy: An Analysis of over 4800 Dogs
Published in Veterinary sciences (01-07-2023)“…Age-related somatic genomic alterations in hematopoietic cell lines have been well characterized in humans; however, this phenomenon has not been well studied…”
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Clinical validation of a blood-based liquid biopsy test integrating cell-free DNA quantification and next-generation sequencing for cancer screening in dogs
Published in Journal of the American Veterinary Medical Association (01-05-2024)“…To validate the performance of a novel, integrated test for canine cancer screening that combines cell-free DNA quantification with next-generation sequencing…”
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Next-generation sequencing-based liquid biopsy may be used for detection of residual disease and cancer recurrence monitoring in dogs
Published in American journal of veterinary research (01-03-2024)“…The purpose of this study was to evaluate the performance of a next-generation sequencing-based liquid biopsy test for cancer monitoring in dogs. Pre- and…”
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Clinical experience with next-generation sequencing-based liquid biopsy testing for cancer detection in dogs: a review of 1,500 consecutive clinical cases
Published in Journal of the American Veterinary Medical Association (01-06-2023)“…To review ordering patterns, positivity rates, and outcome data for a subset of consecutive samples submitted for a commercially available, blood-based…”
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Abstract 3377: Liquid biopsy analysis reveals orthologs of actionable human cancer variants in dogs
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Genotype-matched therapeutics have become widely adopted in the management of human cancers and can be guided by testing tumor tissue or cell-free DNA…”
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Abstract A028: Incidental detection of age-related somatic genomic alterations in blood samples from dogs with and without cancer
Published in Cancer research (Chicago, Ill.) (15-01-2023)“…Abstract The concept of age-related somatic alterations in the blood or bone marrow of humans, commonly referred to as clonal hematopoiesis of indeterminate…”
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Abstract A16: Liquid biopsy for the detection and characterization of canine lymphoma
Published in Blood cancer discovery (06-09-2022)“…Abstract Lymphoma is the most common hematologic malignancy in dogs, with some subtypes being highly similar to their human counterparts in terms of molecular,…”
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Non-Invasive Prenatal Chromosomal Aneuploidy Testing - Clinical Experience: 100,000 Clinical Samples: e109173
Published in PloS one (01-10-2014)“…Objective As the first laboratory to offer massively parallel sequencing-based noninvasive prenatal testing (NIPT) for fetal aneuploidies, Sequenom…”
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