Search Results - "Hicks, Chindo"
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Cervical cancer in low and middle‑income countries (Review)
Published in Oncology letters (01-09-2020)“…Cervical cancer is a malignant tumour that occurs in the cervix and is classified into two histological types, adenocarcinoma and squamous cell carcinoma…”
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2
Integrating germline and somatic variation information using genomic data for the discovery of biomarkers in prostate cancer
Published in BMC cancer (14-03-2019)“…Prostate cancer (PCa) is the most common diagnosed malignancy and the second leading cause of cancer-related deaths among men in the United States…”
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3
Resveratrol and prostate cancer: Promising role for microRNAs
Published in Molecular nutrition & food research (01-08-2011)“…Scope: Resveratrol (Res) has anticancer activity in prostate cancer (PCa), which can be attributed to modulation of microRNAs (miRNAs/miRs). miRNAs/miRs are…”
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4
Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells
Published in Frontiers in immunology (14-07-2021)“…COVID-19 ranges from asymptomatic in 35% of cases to severe in 20% of patients. Differences in the type and degree of inflammation appear to determine the…”
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5
Inferring Personalized and Race-Specific Causal Effects of Genomic Aberrations on Gleason Scores: A Deep Latent Variable Model
Published in Frontiers in oncology (13-03-2020)“…Extensive research has examined socioeconomic factors influencing prostate cancer (PCa) disparities. However, to what extent molecular and genetic mechanisms…”
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Novel putative drivers revealed by targeted exome sequencing of advanced solid tumors
Published in PloS one (23-03-2018)“…Next generation sequencing (NGS) is becoming increasingly integrated into oncological practice and clinical research. NGS methods have also provided evidence…”
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CpG Site-Based Signature Predicts Survival of Colorectal Cancer
Published in Biomedicines (01-12-2022)“…A critical unmet medical need in clinical management of colorectal cancer (CRC) pivots around lack of noninvasive and or minimally invasive techniques for…”
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8
Bioinformatics characterization of variants of uncertain significance in pediatric sensorineural hearing loss
Published in Frontiers in pediatrics (21-02-2024)“…Rapid advancements in Next Generation Sequencing (NGS) and bioinformatics tools have allowed physicians to obtain genetic testing results in a more rapid,…”
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Cross-talk between Notch and the Estrogen Receptor in Breast Cancer Suggests Novel Therapeutic Approaches
Published in Cancer research (Chicago, Ill.) (01-07-2008)“…High expression of Notch-1 and Jagged-1 mRNA correlates with poor prognosis in breast cancer. Elucidating the cross-talk between Notch and other major breast…”
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10
Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer
Published in Frontiers in immunology (13-10-2023)“…Triple-negative breast cancer (TNBC) comprises a heterogeneous group of clinically aggressive tumors with high risk of recurrence and metastasis. Current…”
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11
HER3 targeting augments the efficacy of panobinostat in claudin-low triple-negative breast cancer cells
Published in NPJ precision oncology (03-08-2023)“…Patients with triple-negative breast cancer (TNBC) have a poor prognosis and high relapse rate due to limited therapeutic options. This study was conducted to…”
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12
Interactions between Germline and Somatic Mutated Genes in Aggressive Prostate Cancer
Published in Prostate cancer (01-01-2019)“…Prostate cancer (PCa) is the most common diagnosed malignancy and the second leading cause of cancer-related deaths among men in the USA. Advances in…”
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13
PCa-Clf: A Classifier of Prostate Cancer Patients into Patients with Indolent and Aggressive Tumors Using Machine Learning
Published in Machine learning and knowledge extraction (01-12-2023)“…A critical unmet medical need in prostate cancer (PCa) clinical management centers around distinguishing indolent from aggressive tumors. Traditionally,…”
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14
How can academic health science centers help to increase diversity in the STEM professions?
Published in Frontiers in education (Lausanne) (01-03-2024)“…In the United States, great inequities exist within the science, technology, engineering, and math (STEM) fields in individuals who self-identify as belonging…”
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15
Racial Disparity and Social Determinants in Receiving Timely Surgery Among Stage I-IIIA Non-small Cell Lung Cancer Patients in a U.S. Southern State
Published in Frontiers in public health (02-06-2021)“…Delayed surgery is associated with worse lung cancer outcomes. Social determinants can influence health disparities. This study aimed to examine the potential…”
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16
Integrative Analysis of MicroRNA-Mediated Gene Signatures and Pathways Modulating White Blood Cell Count in Childhood Acute Lymphoblastic Leukemia
Published in Biomarker Insights (2017)“…MicroRNAs (miRNAs) regulate the expression of protein-coding genes and represent potential biomarkers for childhood acute lymphoblastic leukemia (ALL)…”
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An Integrative Genomics Approach for Associating Genome-Wide Association Studies Information With Localized and Metastatic Prostate Cancer Phenotypes
Published in Biomarker Insights (2017)“…High-throughput genotyping has enabled discovery of genetic variants associated with an increased risk of developing prostate cancer using genome-wide…”
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18
"Omics" data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy
Published in BMC medical genomics (12-12-2018)“…Large-scale "omics" datasets have not been leveraged and integrated with functional analyses to discover potential drivers of cardiomyopathy. This study…”
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Delineation of the Germline and Somatic Mutation Interaction Landscape in Triple-Negative and Non-Triple-Negative Breast Cancer
Published in International journal of genomics (2020)“…Background. Breast cancer development and progression involve both germline and somatic mutations. High-throughput genotyping and next-generation sequencing…”
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Breast Cancer Type Classification Using Machine Learning
Published in Journal of personalized medicine (20-01-2021)“…Breast cancer is a heterogeneous disease defined by molecular types and subtypes. Advances in genomic research have enabled use of precision medicine in…”
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