Search Results - "Hickok, Jason R"

Epigenetics: The third pillar of nitric oxide signaling by Socco, Samantha, Bovee, Rhea C., Palczewski, Marianne B., Hickok, Jason R., Thomas, Douglas D.

“…The three pillars of nitric oxide signaling. The first “pillar” of nitric oxide signaling is the interactions of NO with heme-containing proteins, most notably…”
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Nitric Oxide Modifies Global Histone Methylation by Inhibiting Jumonji C Domain-containing Demethylases by Hickok, Jason R., Vasudevan, Divya, Antholine, William E., Thomas, Douglas D.

“…Methylation of lysine residues on histone tails is an important epigenetic modification that is dynamically regulated through the combined effects of…”
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Dinitrosyliron complexes are the most abundant nitric oxide-derived cellular adduct: biological parameters of assembly and disappearance by Hickok, Jason R., Sahni, Sumit, Shen, Hong, Arvind, Akanksha, Antoniou, Chloe, Fung, Leslie W.M., Thomas, Douglas D.

“…It is well established that nitric oxide (•NO) reacts with cellular iron and thiols to form dinitrosyliron complexes (DNIC). Little is known, however,…”
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In vivo circadian rhythms in gonadotropin-releasing hormone neurons by Hickok, Jason R, Tischkau, Shelley A

“…Although it is generally accepted that the circadian clock provides a timing signal for the luteinizing hormone (LH) surge, mechanistic explanations of this…”
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Oxygen dependence of nitric oxide-mediated signaling by Hickok, Jason R, Vasudevan, Divya, Jablonski, Kate, Thomas, Douglas D

“…Nitric oxide (•NO) is a biologically important short-lived free radical signaling molecule. Both the enzymatic synthesis and the predominant forms of cellular…”
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The luteinizing hormone surge regulates circadian clock gene expression in the chicken ovary by Tischkau, Shelley A, Howell, Rebecca E, Hickok, Jason R, Krager, Stacey L, Bahr, Janice M

“…The molecular circadian clock mechanism is highly conserved between mammalian and avian species. Avian circadian timing is regulated at multiple oscillatory…”
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Nitric oxide reduces oxidative stress in cancer cells by forming dinitrosyliron complexes by Sahni, Sumit, Hickok, Jason R., Thomas, Douglas D.

“…The chelatable iron pool (CIP) is a small but chemically significant fraction of total cellular iron. While this dynamic population of iron is limited, it is…”
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Nitric oxide and cancer therapy: the emperor has NO clothes by Hickok, Jason R, Thomas, Douglas D

“…The role of nitric oxide (NO()) as a mediator of cancer phenotype has led researchers to investigate strategies for manipulating in vivo production and…”
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Vorinostat exhibits anticancer effects in triple-negative breast cancer cells by preventing nitric oxide-driven histone deacetylation by Palczewski, Marianne B, Kuschman, Hannah Petraitis, Bovee, Rhea, Hickok, Jason R, Thomas, Douglas D

“…Triple-negative breast cancers (TNBC) that produce nitric oxide (NO) are more aggressive, and the expression of the inducible form of nitric oxide synthase…”
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Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: role of chelatable iron by Hickok, Jason R, Sahni, Sumit, Mikhed, Yuliya, Bonini, Marcelo G, Thomas, Douglas D

“…N-Myc downstream-regulated gene 1 (NDRG1) is a ubiquitous cellular protein that is up-regulated under a multitude of stress and growth-regulatory conditions…”
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Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications by Vasudevan, Divya, Hickok, Jason R, Bovee, Rhea C, Pham, Vy, Mantell, Lin L, Bahroos, Neil, Kanabar, Pinal, Cao, Xing-Jun, Maienschein-Cline, Mark, Garcia, Benjamin A, Thomas, Douglas D

“…Altered nitric oxide (•NO) metabolism underlies cancer pathology, but mechanisms explaining many •NO-associated phenotypes remain unclear. We have found that…”
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Is S-nitrosocysteine a true surrogate for nitric oxide? by Hickok, Jason R, Vasudevan, Divya, Thatcher, Gregory R J, Thomas, Douglas D

“…S-Nitrosothiol (RSNO) formation is one manner by which nitric oxide (•NO) exerts its biological effects. There are several proposed mechanisms of formation of…”
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Requirement of Mammalian Timeless for Circadian Rhythmicity by Barnes, Jessica W., Tischkau, Shelley A., Barnes, Jeffrey A., Mitchell, Jennifer W., Burgoon, Penny W., Hickok, Jason R., Gillette, Martha U.

“…Despite a central circadian role in Drosophila for the transcriptional regulator Timeless (dTim), the relevance of mammalian Timeless (mTim) remains equivocal…”
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Nitric oxide reduces oxidative stress in cancers cells by forming dinitrosyliron complexes by Sahni, Sumit, Hickok, Jason R., Thomas, Douglas D.

“…The chelatable iron pool (CIP) is a small but chemically significant fraction of total cellular iron. While this dynamic population of iron is limited, it is…”
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Nitric Oxide Modifies Histone Methylation Patterns by Inhibiting Jumonji C Domain Containing Demethylases by Hickok, Jason R., Vasudevan, Divya, Thomas, Douglas D.

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Oxygen Regulates Nitric Oxide-Mediated Signaling by Determining the Rate of NO Synthesis and Metabolism by Mikhed, Yuliya, Hickok, Jason R., Thomas, Douglas D.

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Nitric Oxide Suppresses Tumor Cell Migration Through N-Myc Downstream Regulated Gene-1 (NDRG1) Expression: the Role of Chelatable Iron by Hickok, Jason R., Sahni, Sumit, Mikhed, Yuliya, Thomas, Douglas D.

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Contrasting Mechanisms of Cellular S-Nitrosothiol Formation From •NO and CysNO: the Role of Chelatable Iron by Vasudevan, Divya, Hickok, Jason R, Thomas, Douglas D

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Nitric Oxide Suppresses Tumor Cell Migration through N-Myc Downstream-regulated Gene-1 (NDRG1) Expression by Hickok, Jason R., Sahni, Sumit, Mikhed, Yuliya, Bonini, Marcelo G., Thomas, Douglas D.

“…N-Myc downstream-regulated gene 1 (NDRG1) is a ubiquitous cellular protein that is up-regulated under a multitude of stress and growth-regulatory conditions…”
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The Creation and Rapid Deployment of a Preparedness Plan for Ebola Virus Disease: Lessons from a Large Healthcare System by Moody, Julia, Cormier, Scott, Hickok, Jason, RN, Septimus, Edward, MD, Chari, Ravi, MD, Perlin, Jonathan, MD, PhD

“…The first laboratory-confirmation of Ebola in the United States on September 30, 2014 stimulated nationwide action. In a large healthcare system composed of…”
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