Search Results - "Hickling, Stephen"

Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection by Hoffmann, Matthias, Pantazis, Nikos, Martin, Genevieve E, Hickling, Stephen, Hurst, Jacob, Meyerowitz, Jodi, Willberg, Christian B, Robinson, Nicola, Brown, Helen, Fisher, Martin, Kinloch, Sabine, Babiker, Abdel, Weber, Jonathan, Nwokolo, Nneka, Fox, Julie, Fidler, Sarah, Phillips, Rodney, Frater, John

“…The rate at which HIV-1 infected individuals progress to AIDS is highly variable and impacted by T cell immunity. CD8 T cell inhibitory molecules are…”
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Efficacious Early Antiviral Activity of HIV Gag- and Pol-Specific HLA-B2705-Restricted CD8+ T Cells by PAYNE, Rebecca P, KLØVERPRIS, Henrik, LUZZI, Graz, EDWARDS, Anne, PHILLIPS, Rodney, PRADO, Julia G, GOULDER, Philip J. R, SACHA, Jonah B, BRUMME, Zabrina, BRUMME, Chanson, BUUS, Søren, SIMS, Stuart, HICKLING, Stephen, RIDDELL, Lynn, FABIAN CHEN

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Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations by Huang, Kuan-Hsiang Gary, Goedhals, Dominique, Carlson, Jonathan M, Brockman, Mark A, Mishra, Swati, Brumme, Zabrina L, Hickling, Stephen, Tang, Christopher S W, Miura, Toshiyuki, Seebregts, Chris, Heckerman, David, Ndung'u, Thumbi, Walker, Bruce, Klenerman, Paul, Steyn, Dewald, Goulder, Philip, Phillips, Rodney, van Vuuren, Cloete, Frater, John

“…We lack the understanding of why HIV-infected individuals in South Africa progress to AIDS. We hypothesised that in end-stage disease there is a shifting…”
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Increased levels of CD4 T-cell activation in individuals with CXCR4 using viruses in primary HIV-1 infection by HAMLYN, Elizabeth, HICKLING, Stephen, PORTER, Kholoud, FRATER, John, PHILLIPS, Rodney, ROBINSON, Mark, MACKIE, Nicola E, KAYE, Steve, MCCLURE, Myra, FIDLER, Sarah

“…CXCR4-tropic (X4) HIV-1 variants are associated with faster disease progression compared with CCR5-tropic variants; however, the mechanism for this is unclear…”
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Efficacious early antiviral activity of HIV Gag- and Pol-specific HLA-B 2705-restricted CD8+ T cells by Payne, Rebecca P, Kløverpris, Henrik, Sacha, Jonah B, Brumme, Zabrina, Brumme, Chanson, Buus, Søren, Sims, Stuart, Hickling, Stephen, Riddell, Lynn, Chen, Fabian, Luzzi, Graz, Edwards, Anne, Phillips, Rodney, Prado, Julia G, Goulder, Philip J R

“…The association between HLA-B 2705 and the immune control of human immunodeficiency virus type 1 (HIV-1) has previously been linked to the targeting of the…”
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