Search Results - "Hickey, W F"

The Neuropathological and Behavioral Consequences of Intraspinal Microglial/Macrophage Activation by POPOVICH, P G, GUAN, Z, MCGAUGHY, V, FISHER, L, HICKEY, W F, BASSO, D M

“…Activated microglia and macrophages (CNS macrophages) have been implicated in the secondary or “bystander” pathology (e.g. axon injury, demyelination) that…”
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CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses by Kielian, T, Barry, B, Hickey, W F

“…We have developed a mouse brain abscess model by using Staphylococcus aureus, one of the main etiologic agents of brain abscesses in humans. Direct damage to…”
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Dissociation of microglial activation and neuropathic pain behaviors following peripheral nerve injury in the rat by Colburn, R.W, DeLeo, J.A, Rickman, A.J, Yeager, M.P, Kwon, P, Hickey, W.F

“…Peripheral nerve injury commonly leads to neuropathic pain states fostered, in part, by neuroimmunologic events. We used two models of neuropathic pain (L5…”
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T-lymphocyte entry into the central nervous system by Hickey, W F, Hsu, B L, Kimura, H

“…The entry of T-lymphocytes into the parenchyma of the central nervous system is a critical early feature in the pathogenesis of many experimental and…”
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Proinflammatory Cytokine, Chemokine, and Cellular Adhesion Molecule Expression during the Acute Phase of Experimental Brain Abscess Development by Kielian, Tammy, Hickey, William F.

“…Brain abscess represents the infectious disease sequelae associated with the influx of inflammatory cells and activation of resident parenchymal cells in the…”
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Diminished virulence of an alpha-toxin mutant of Staphylococcus aureus in experimental brain abscesses by KIELIAN, Tammy, CHEUNG, Ambrose, HICKEY, William F

“…Staphylococcus aureus is one of the major etiologic agents of brain abscesses in humans, occasionally leading to focal neurological deficits and even death…”
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Basic principles of immunological surveillance of the normal central nervous system by Hickey, William F.

“…Unlike most bodily organs, the central nervous system (CNS) exists behind a blood–tissue barrier designed to minimize the passage of cells and macromolecules…”
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bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS by MERRY, D. E, VEIS, D. J, HICKEY, W. F, KROSMEYER, S. J

“…Cell death is a common feature of neural development in all vertebrates. The bcl-2 proto-oncogene has been shown to protect a variety of cell types from…”
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Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice by Cross, A H, Misko, T P, Lin, R F, Hickey, W F, Trotter, J L, Tilton, R G

“…Previous work from our laboratory localized nitric oxide to the affected spinal cords of mice with experimental autoimmune encephalomyelitis, a prime model for…”
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Perivascular Microglial Cells of the CNS are Bone Marrow-Derived and Present Antigen in vivo by Hickey, William F., Kimura, Hiromitsu

“…A crucial question in the study of immunological reactions in the central nervous system (CNS) concerns the identity of the parenchymal cells that function as…”
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Bone marrow derived elements and resident microglia in brain inflammation by Lassmann, H, Schmied, M, Vass, K, Hickey, W F

“…Infection of the central nervous (CNS) system by the human immunodeficiency virus (HIV) depends on the migration of infected hematogenous cells into the brain…”
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Microglial cells are a component of the perivascular glia limitans by Lassmann, H, Zimprich, F, Vass, K, Hickey, W F

“…The ultrastructural relation between microglial cells and cerebral blood vessels was studied in rat brains by immune electron microscopy using antibodies…”
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The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis by Bauer, J, Huitinga, I, Zhao, W, Lassmann, H, Hickey, W F, Dijkstra, C D

“…Clinical signs of experimental autoimmune encephalomyelitis (EAE) in rats can be suppressed by treatment with liposomes containing dichloromethylene…”
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Traffic of hematogenous cells through the central nervous system by Williams, K C, Hickey, W F

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Unmasking of an unusual myelin basic protein epitope during the process of myelin degeneration in humans: a potential mechanism for the generation of autoantigens by Matsuo, A, Lee, GC, Terai, K, Takami, K, Hickey, WF, McGeer, EG, McGeer, PL

“…A rabbit antiserum (anti-EP), induced against a synthetic peptide corresponding to residues 68 to 86 of guinea pig myelin basic protein, powerfully…”
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Experimental congestive heart failure produced by rapid ventricular pacing in the dog: cardiac effects by WILSON, J. R, DOUGLAS, P, HICKEY, W. F, LANOCE, V, FERRARO, N, ALI MUHAMMAD, REICHEK, N

“…Chronic rapid ventricular pacing in the dog reportedly produces a useful preparation of low-output heart failure. However, little information is available…”
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Leukocyte traffic in the central nervous system: the participants and their roles by Hickey, William F.

“…While the central nervous system has long been considered immunologically privileged, over the past decade it has become evident that a wide variety of…”
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Monoclonal antibody analysis of MHC expression in human brain biopsies: tissue ranging from "histologically normal" to that showing different levels of glial tumor involvement by Lampson, LA, Hickey, WF

“…The expression of class I and class II MHC products in human brain was studied. Radioimmunoassay confirmed weak expression of HLA-A,B,C and beta…”
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Bone marrow-derived elements in the peripheral nervous system. An immunohistochemical and ultrastructural investigation in chimeric rats by Vass, K, Hickey, W F, Schmidt, R E, Lassmann, H

“…Currently available studies on the peripheral nervous system (PNS) give little information on the presence, distribution, turnover and function of bone…”
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Central nervous system damage, monocytes and macrophages, and neurological disorders in AIDS by WILLIAMS, Kenneth C, HICKEY, William F

“…This review focuses on the role of the extended macrophage/monocyte family in the central nervous system during HIV or SIV infection. The accumulated data,…”
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