Search Results - "Hibiya, Shuji"
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Serum Leucine-Rich α2 Glycoprotein: A Novel Biomarker for Transmural Inflammation in Crohn's Disease
Published in The American journal of gastroenterology (01-06-2023)“…Leucine-rich alpha-2 glycoprotein (LRG) is a newly studied biomarker for inflammatory diseases. This study aimed to investigate whether LRG can be used for…”
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Serum Leucine-Rich α2 Glycoprotein: A Novel Biomarker For Small Bowel Mucosal Activity in Crohn’s Disease
Published in Clinical gastroenterology and hepatology (01-05-2022)“…Active lesions in the small bowel (SB) have been independently associated with poorer prognoses in patients with Crohn’s disease (CD)1; however, there has been…”
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Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids
Published in Journal of gastroenterology (01-07-2019)“…Background Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with an intractable, recurrent course. The goal of UC therapy is to target…”
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Higher concentrations of cytokine blockers are needed to obtain small bowel mucosal healing during maintenance therapy in Crohn's disease
Published in Alimentary pharmacology & therapeutics (01-10-2021)“…Summary Background Several studies have reported a positive correlation between serum drug concentrations and endoscopic remission in patients with Crohn's…”
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TP53 Mutation by CRISPR System Enhances the Malignant Potential of Colon Cancer
Published in Molecular cancer research (01-07-2019)“…Tumor protein p53 (TP53) mutation is a well-known occurrence at the late phase of carcinogenesis during the adenoma-carcinoma sequence of a sporadic colon…”
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Importance of Telomere Shortening in the Pathogenesis of Ulcerative Colitis: A New Treatment From the Aspect of Telomeres in Intestinal Epithelial Cells
Published in Journal of Crohn's and colitis (28-01-2022)“…Abstract Background and Aims Ulcerative colitis [UC] is a chronic inflammatory disease of the colon with frequent relapses. Telomere shortening in intestinal…”
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Transmural Remission Characterized by High Biologic Concentrations Demonstrates Better Prognosis in Crohn’s Disease
Published in Journal of Crohn's and colitis (16-06-2023)“…Abstract Background The importance and pathophysiology of transmural healing in patients with Crohn’s disease [CD] remains to be verified. We aimed to examine…”
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5‐aminosalicylate–intolerant patients are at increased risk of colectomy for ulcerative colitis
Published in Alimentary pharmacology & therapeutics (01-01-2021)“…Summary Background Although 5‐aminosalicylate (5‐ASA) is the therapy of first choice in ulcerative colitis (UC), some patients cannot tolerate it because of…”
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Intestinal phenotype is maintained by Atoh1 in the cancer region of intraductal papillary mucinous neoplasm
Published in Cancer science (01-02-2021)“…Intraductal papillary mucinous neoplasm (IPMN) is a precancerous lesion of pancreatic cancer. Although there are 4 types of IPMN, among which intestinal‐type…”
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Schlafen 11 Is a Novel Target for Mucosal Regeneration in Ulcerative Colitis
Published in Journal of Crohn's and colitis (25-09-2021)“…Abstract Background and Aims Ulcerative colitis [UC] is a chronic inflammatory disease of the colon with an intractable course. Although the goal of UC therapy…”
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Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn's disease
Published in BMC gastroenterology (04-05-2022)“…Small intestinal stricture is a major cause for surgery in Crohn's disease (CD). Endoscopic balloon dilation (EBD) is performed for small intestinal strictures…”
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Deep neural network for video colonoscopy of ulcerative colitis: a cross-sectional study
Published in The lancet. Gastroenterology & hepatology (01-03-2022)“…A combination of endoscopic and histological evaluation is important in the management of patients with ulcerative colitis. We aimed to adapt our previous deep…”
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Combination of leucine-rich alpha-2 glycoprotein and fecal markers detect Crohn’s disease activity confirmed by balloon-assisted enteroscopy
Published in Intestinal research (01-01-2024)“…Background/Aims: Endoscopic activity confirmed by enteroscopy is associated with poor clinical outcome in Crohn’s disease (CD). We investigated which of the…”
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Long-term efficacy and safety of tofacitinib in patients with ulcerative colitis: 3-year results from a real-world study
Published in Intestinal research (01-07-2024)“…Background/Aims: The efficacy and safety of tofacitinib for the treatment of refractory ulcerative colitis (UC) has been demonstrated in clinical trials…”
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Intravenous tacrolimus is a superior induction therapy for acute severe ulcerative colitis compared to oral tacrolimus
Published in BMC gastroenterology (23-12-2021)“…Intravenous corticosteroid is the mainstay for managing acute severe ulcerative colitis, but one-third of patients do not respond to intravenous…”
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Hemorrhagic gastric ulcer in a patient with Behcet's disease successfully treated with infliximab
Published in DEN open (01-04-2023)“…Behcet's disease (BD) is a multisystem immune‐mediated inflammatory disorder that occasionally involves the gastrointestinal tract. Reports on gastrointestinal…”
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Rapid prediction of 1-year efficacy of tofacitinib for treating refractory ulcerative colitis
Published in Intestinal research (01-01-2021)“…KCI Citation Count: 0…”
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A case of venous stasis colitis possibly caused by eplerenone
Published in Clinical journal of gastroenterology (01-02-2023)“…A 50-year-old man was referred to our hospital for colitis with abdominal pain and diarrhea that had persisted for more than 8 months. 9 months earlier, he had…”
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Influence of chronic inflammation on the malignant phenotypes and the plasticity of colorectal cancer cells
Published in Biochemistry and biophysics reports (01-07-2021)“…Sporadic adenoma or adenocarcinoma is often detected during endoscopic surveillance of patients with ulcerative colitis (UC). However, it is occasionally…”
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Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line
Published in Cancer science (01-08-2015)“…Patients with inflammatory bowel disease (IBD) have an increased risk of developing colitis‐associated colorectal cancer (CAC). CAC cells often develop…”
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