Search Results - "Hibbitt, Olivia"

Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels by Sacilotto, Natalia, Castillo, Josefa, Riffo-Campos, Ángela L, Flores, Juana M, Hibbitt, Olivia, Wade-Martins, Richard, López, Carlos, Rodrigo, M Isabel, Franco, Luis, López-Rodas, Gerardo

“…The prognosis of hepatocellular carcinoma patients is usually poor, the size of tumors being a limiting factor for surgical treatments. Present results suggest…”
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Delivery of large genomic DNA inserts >100 kb using HSV-1 amplicons by Hibbitt, Olivia C, Wade-Martins, Richard

“…The principal aim of gene therapy for recessive genetic diseases is to supplement the loss of function of an endogenous gene. For the treatment of many…”
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Long-term Physiologically Regulated Expression of the Low-density Lipoprotein Receptor In Vivo Using Genomic DNA Mini-gene Constructs by Hibbitt, Olivia C, McNeil, Eileen, Lufino, Michele MP, Seymour, Len, Channon, Keith, Wade-Martins, Richard

“…Familial hypercholesterolemia (FH) is a condition caused by mutations in the low-density lipoprotein receptor (LDLR) gene. Expression of LDLR is highly…”
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Delivery and long-term expression of a 135 kb LDLR genomic DNA locus in vivo by hydrodynamic tail vein injection by Hibbitt, Olivia C., Harbottle, Richard P., Waddington, Simon N., Bursill, Christine A., Coutelle, Charles, Channon, Keith M., Wade-Martins, Richard

“…Background The delivery of a complete genomic DNA locus in vivo may prove advantageous for complementation gene therapy, especially when physiological…”
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In Vivo Gene Transfer by Electroporation Allows Expression of a Fluorescent Transgene in Hamster Testis and Epididymal Sperm and Has No Adverse Effects upon Testicular Integrity or Sperm Quality by HIBBITT, Olivia, COWARD, Kevin, KUBOTA, Hiroki, PRATHALINGHAM, Nilendran, HOLT, William, KOHRI, Kenjiro, PARRINGTON, John

“…The study of gene function in testis and sperm has been greatly assisted by transgenic mouse models. Recently, an alternative way of expressing transgenes in…”
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Making good on the promise of genomics in healthcare: the NSW Health perspective by Willcox, Deb, Trent, Ronald J A, Lyons, Nigel, Meldrum, Cliff, Kennedy, Peter, Lee, Tamara, Berman, Yemima, Burgess, Bronwyn, Cannings, John William, Canova, Martin Joseph, Halliburton, Celia, Hibbitt, Olivia, Norris, Sarah Karen, Penna, Antonio, Perkins, Andrew, Pilowsky, Eva, Rushton, Shelley

“…NSW Health is implementing genomics as a mainstream component of clinical care. The strategic, holistic approach is considering infrastructure, data governance…”
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A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor by Kerr, Alastair G, Tam, Lawrence C S, Hale, Ashley B, Cioroch, Milena, Douglas, Gillian, Agkatsev, Sarina, Hibbitt, Olivia, Mason, Joseph, Holt-Martyn, James, Bataille, Carole J R, Wynne, Graham M, Channon, Keith M, Russell, Angela J, Wade-Martins, Richard

“…Hypercholesterolemia remains one of the leading risk factors for the development of cardiovascular disease. Many large double-blind studies have demonstrated…”
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High capacity extrachromosomal gene expression vectors by Hibbitt, Olivia, Wade-Martins, Richard

“…Extrachromosomal gene expression vectors that contain native genomic gene expression elements have numerous advantages over traditional integrating mini-gene…”
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Expression of a fluorescent recombinant form of sperm protein phospholipase C zeta in mouse epididymal sperm by in vivo gene transfer into the testis by Coward, Kevin, Kubota, Hiroki, Hibbitt, Olivia, McIlhinney, Jeff, Kohri, Kenjiro, Parrington, John

“…To use in vivo gene transfer into the testis by electroporation to express a fluorescent recombinant form of a testis-specific gene in the mature epididymal…”
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Growth Arrest Specific 1 (Gas1) Gene Overexpression in Liver Reduces the In Vivo Progression of Murine Hepatocellular Carcinoma and Partially Restores Gene Expression Levels: e0132477 by Sacilotto, Natalia, Castillo, Josefa, Riffo-Campos, Angela L, Flores, Juana M, Hibbitt, Olivia, Wade-Martins, Richard, Lopez, Carlos, Rodrigo, M Isabel, Franco, Luis, Lopez-Rodas, Gerardo

“…The prognosis of hepatocellular carcinoma patients is usually poor, the size of tumors being a limiting factor for surgical treatments. Present results suggest…”
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Teleost fish spermatozoa contain a cytosolic protein factor that induces calcium release in sea urchin egg homogenates and triggers calcium oscillations when injected into mouse oocytes by Coward, Kevin, Campos-Mendoza, Antonio, Larman, Mark, Hibbitt, Olivia, McAndrew, Brendan, Bromage, Niall, Parrington, John

“…Established studies in a variety of organisms including amphibians, fish, ascidians, nemerteans, echinoderms, mammals, and even a species of flowering plant,…”
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In Vivo Gene Transfer by Electroporation Allows Expression of a Fluorescent Transgene in Hamster Testis and Epididymal Sperm and Has No Adverse Effects upon Testicular Integrity or Sperm Quality1 by Hibbitt, Olivia, Coward, Kevin, Kubota, Hiroki, Prathalingham, Nilendran, Holt, William, Kohri, Kenjiro, Parrington, John

“…The study of gene function in testis and sperm has been greatly assisted by transgenic mouse models. Recently, an alternative way of expressing transgenes in…”
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Cloning of a novel phospholipase C-δ isoform from pacific purple sea urchin ( Strongylocentrotus purpuratus) gametes and its expression during early embryonic development by Coward, Kevin, Owen, Helen, Poustka, Albert J, Hibbitt, Olivia, Tunwell, Richard, Kubota, Hiroki, Swann, Karl, Parrington, John

“…Calcium (Ca 2+) is a ubiquitous intracellular messenger, controlling a diverse range of cellular processes, including fertilization and development of the…”
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