Search Results - "Heynekamp, Justin J."

Substituted trans-Stilbenes, Including Analogues of the Natural Product Resveratrol, Inhibit the Human Tumor Necrosis Factor Alpha-Induced Activation of Transcription Factor Nuclear Factor KappaB by Heynekamp, Justin J, Weber, Waylon M, Hunsaker, Lucy A, Gonzales, Amanda M, Orlando, Robert A, Deck, Lorraine M, Vander Jagt, David L

“…The transcription factor nuclear factor kappaB (NF-κB), which regulates expression of numerous antiinflammatory genes as well as genes that promote development…”
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Isocoumarin-based inhibitors of pancreatic cholesterol esterase by Heynekamp, Justin J., Hunsaker, Lucy A., Vander Jagt, Thomas A., Royer, Robert E., Deck, Lorraine M., Vander Jagt, David L.

“…Pancreatic cholesterol esterase (CEase), which is secreted from the exocrine pancreas, is a serine hydrolase that aids in the bile salt-dependent hydrolysis of…”
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TPA-induced up-regulation of activator protein-1 can be inhibited or enhanced by analogs of the natural product curcumin by Weber, Waylon M., Hunsaker, Lucy A., Gonzales, Amanda M., Heynekamp, Justin J., Orlando, Robert A., Deck, Lorraine M., Vander Jagt, David L.

“…The activator protein-1 (AP-1) family of transcription factors, including the most common member c-Jun-c-Fos, participates in regulation of expression of…”
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Spectroscopic and Photophysical Characterization of Fluorescent Chemosensors for Monosaccharides Based on N -Phenylboronic Acid Derivatives of 1,8-Naphthalimide by DiCesare, Nicolas, Adhikari, Devi P, Heynekamp, Justin J, Heagy, Michael D, Lakowicz, Joseph R

“…Spectroscopic and photophysical properties of two fluorescent probes for monosaccharides are presented. Probes are based on the -phenyl-1,8-naphthalimide…”
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Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator by Heynekamp, Justin J, Hunsaker, Lucy A, Vander Jagt, Thomas A, Deck, Lorraine M, Vander Jagt, David L

“…Urokinase-type plasminogen activator (uPA) plays a major role in extracellular proteolytic events associated with tumor cell growth, migration and…”
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Serine hydrolase inhibitors as therapeutics for cancer and heart disease by Heynekamp, Justin J

“…Cancer and atherosclerotic heart disease are two health problems affecting millions of people each year. A therapeutic approach to these two diseases is the…”
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