Search Results - "Heyman, Rich A."

Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid by Farmer, Luc J., Zhi, Lin, Jeong, Susan, Lamph, William W., Osburn, Deborah L., Croston, Glenn, Flatten, Karen S., Heyman, Rich A., Nadzan, Alex M.

“…A series of novel cyclopropanyl methyl hexadienoic acid retinoids was designed and prepared. These compounds exhibited either selective activity as RXR…”
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Synthesis and structure-activity relationships of potent retinoid X receptor ligands by Farmer, Luc J., Jeong, Susan, Kallel, E.Adam, Canan Koch, Stacie S., Croston, Glenn E., Flatten, Karen S., Heyman, Rich A., Nadzan, Alex M.

“…A series of potent retinoid X receptor (RXR) selective ligands was designed and prepared. The lead compound 7a showed good binding (K i; 20–50 nM) and…”
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Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands by Farmer, Luc J., Lin Zhi, Susan Jeong, Adam Kallel, E., Croston, Glenn, Flatten, Karen S., Heyman, Rich A., Nadzan, Alex M.

“…A series of potent retinoid X receptor (RXR) selective ligands were designed and prepared. The lead compound 6a, showed good binding (K d; 3–7 nM) and…”
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