Search Results - "Heyll, Kathrin"
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MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1
Published in Nature medicine (01-04-2014)“…Atherosclerotic lesions develop preferentially at sites of disturbed blood flow. As shown by Christian Weber and his coworkers, this predilection stems from…”
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MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages
Published in The Journal of clinical investigation (01-11-2012)“…Macrophages in atherosclerotic plaques drive inflammatory responses, degrade lipoproteins, and phagocytose dead cells. MicroRNAs (miRs) control the…”
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Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium
Published in Cell metabolism (04-05-2011)“…Oxidatively modified low-density lipoprotein (oxLDL) plays a key role in the initiation of atherosclerosis by increasing monocyte adhesion. The mechanism that…”
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Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue
Published in Circulation (New York, N.Y.) (18-03-2014)“…The aim of this study was to determine the role of the chemokine receptor CXCR7 in atherosclerosis and vascular remodeling. CXCR7 is the alternative receptor…”
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Regulation of Csf1r and Bcl6 in macrophages mediates the stage-specific effects of microRNA-155 on atherosclerosis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-04-2015)“…The function of microRNAs is highly context and cell type dependent because of their highly dynamic expression pattern and the regulation of multiple mRNA…”
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The microRNA-342-5p Fosters Inflammatory Macrophage Activation Through an Akt1- and microRNA-155―Dependent Pathway During Atherosclerosis
Published in Circulation (New York, N.Y.) (16-04-2013)“…Atherosclerosis is a chronic inflammatory vascular disease driven by the subendothelial accumulation of macrophages. The mechanism regulating the inflammatory…”
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Abstract 17984: Protective Role of Dicer in Macrophages During Atherogenesis
Published in Circulation (New York, N.Y.) (26-11-2013)“…Abstract only Atherosclerotic lesion development is characterized by the subendothelial accumulation of lipid-laden macrophages. It is known that microRNAs…”
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Abstract P167: CXCR4 Antagonism Is Equally Effective as Sirolimus in Reducing Neointima Formation After Arterial Injury Without Impairing Reendothelialization
Published in Circulation research (09-12-2011)“…Abstract only The chemokine receptor CXCR4 is crucial in neointima formation which is a problem after stent implantation. Drug-eluting stents reduce the…”
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MicroRNA-155 promotes atherosclerosis by repressing BCL6 in macrophages
Published in The Journal of clinical investigation (01-11-2012)“…Macrophages in atherosclerotic plaques drive inflammatory responses, degrade lipoproteins, and phagocytose dead cells. MicroRNAs (miRs) control the…”
Get full text
Journal Article