Search Results - "Heyking, Kristina"

The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma by Heyking, Kristina, Calzada‐Wack, Julia, Göllner, Stefanie, Neff, Frauke, Schmidt, Oxana, Hensel, Tim, Schirmer, David, Fasan, Annette, Esposito, Irene, Müller‐Tidow, Carsten, Sorensen, Poul H., Burdach, Stefan, Richter, Günther H. S.

“…Ewing sarcomas (ES) are highly malignant, osteolytic bone or soft tissue tumors, which are characterized by EWS–ETS translocations and early metastasis to lung…”
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Monocyte Maturation Mediators Upregulate CD83, ICAM-1 and MHC Class 1 Expression on Ewing's Sarcoma, Enhancing T Cell Cytotoxicity by Biele, Emilie, Schober, Sebastian J, Prexler, Carolin, Thiede, Melanie, Heyking, Kristina von, Gassmann, Hendrik, Eck, Jennifer, Xue, Busheng, Burdach, Stefan, Thiel, Uwe

“…Ewing's sarcoma (EwS) is a pediatric solid tumor entity with low somatic mutational burden and a low rate of tumor-infiltrating T cells, indicating a low…”
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Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis by Schmidt, Oxana, Nehls, Nadja, Prexler, Carolin, von Heyking, Kristina, Groll, Tanja, Pardon, Katharina, Garcia, Heathcliff D, Hensel, Tim, Gürgen, Dennis, Henssen, Anton G, Eggert, Angelika, Steiger, Katja, Burdach, Stefan, Richter, Günther H S

“…Histone acetylation and deacetylation seem processes involved in the pathogenesis of Ewing sarcoma (EwS). Here histone deacetylases (HDAC) class I were…”
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T Cells Directed against the Metastatic Driver Chondromodulin-1 in Ewing Sarcoma: Comparative Engineering with CRISPR/Cas9 vs. Retroviral Gene Transfer for Adoptive Transfer by Xue, Busheng, von Heyking, Kristina, Gassmann, Hendrik, Poorebrahim, Mansour, Thiede, Melanie, Schober, Kilian, Mautner, Josef, Hauer, Julia, Ruland, Jürgen, Busch, Dirk H, Thiel, Uwe, Burdach, Stefan E G

“…Ewing sarcoma (EwS) is a highly malignant sarcoma of bone and soft tissue with early metastatic spread and an age peak in early puberty. The prognosis in…”
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Correction to: Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis by Schmidt, Oxana, Nehls, Nadja, Prexler, Carolin, von Heyking, Kristina, Groll, Tanja, Pardon, Katharina, Garcia, Heathcliff D, Hensel, Tim, Gürgen, Dennis, Henssen, Anton G, Eggert, Angelika, Steiger, Katja, Burdach, Stefan, Richter, Günther H S

“…An amendment to this paper has been published and can be accessed via the original article…”
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Ewing Sarcoma-Derived Extracellular Vesicles Impair Dendritic Cell Maturation and Function by Gassmann, Hendrik, Schneider, Kira, Evdokimova, Valentina, Ruzanov, Peter, Schober, Sebastian J., Xue, Busheng, von Heyking, Kristina, Thiede, Melanie, Richter, Guenther H. S., Pfaffl, Michael W., Noessner, Elfriede, Stein, Lincoln D., Sorensen, Poul H., Burdach, Stefan E. G., Thiel, Uwe

“…Ewing sarcoma (EwS) is an aggressive pediatric cancer of bone and soft tissues characterized by scant T cell infiltration and predominance of immunosuppressive…”
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Abstract 3181: Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis by Schmidt, Oxana, Nehls, Nadja, Heyking, Kristina von, Hensel, Tim, Burdach, Stefan, Richter, Günther H.

“…Introduction: Recent evidence demonstrated that a low mutation rate seems a general feature of pediatric cancers. Ewing sarcoma (EwS) is defined by balanced…”
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Abstract 3866: Investigating the role of class I HDACs in Ewing sarcoma pathology by Heyking, Kristina von, Hensel, Tim, Singer, Julia, Schmidt, Oxana, Burdach, Stefan, Richter, Günther H.

“…Introduction: Recent evidence demonstrated that a low mutation rate seems a general feature of pediatric cancers. Ewing sarcoma (ES) is defined by balanced…”
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Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma by Agelopoulos, Konstantin, Richter, Günther H S, Schmidt, Eva, Dirksen, Uta, von Heyking, Kristina, Moser, Benjamin, Klein, Hans-Ulrich, Kontny, Udo, Dugas, Martin, Poos, Kathrin, Korsching, Eberhard, Buch, Thorsten, Weckesser, Matthias, Schulze, Isabell, Besoke, Regina, Witten, Anika, Stoll, Monika, Köhler, Gabriele, Hartmann, Wolfgang, Wardelmann, Eva, Rossig, Claudia, Baumhoer, Daniel, Jürgens, Heribert, Burdach, Stefan, Berdel, Wolfgang E, Müller-Tidow, Carsten

“…A low mutation rate seems to be a general feature of pediatric cancers, in particular in oncofusion gene-driven tumors. Genetically, Ewing sarcoma is defined…”
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Abstract 3973: BRICHOS genes CHM1 and ITM2A maintain an undifferentiated, invasive phenotype in Ewing sarcoma by Heyking, Kristina von, Fasan, Annette, Burdach, Stefan, Richter, Günther H.

“…Ewing sarcomas (ES) are highly malignant, osteolytic bone or soft tissue tumors, which are characterized by ews/ets translocations and early metastasis into…”
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Abstract B03: The endochondral bone protein CHM1 sustains an undifferentiated, invasive phenotype promoting lung metastasis in Ewing sarcoma by Heyking, Kristina von, Calzada-Wack, Julia, Göllner, Stefanie, Schmidt, Oxana, Hensel, Tim, Schirmer, David, Fasan, Annette, Müller-Tidow, Carsten, Sorensen, Poul, Burdach, Stefan, Richter, Günther H.S.

“…Background: Ewing sarcoma (ES), an osteogenic malignancy that mainly affects children and young adults, is characterized by early metastasis to lung and bone…”
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Abstract A51: The HoxD locus: Its contribution to osteogenic phenotype and malignancy of Ewing sarcoma by Richter, Guenther HS, Heyking, Kristina von, Roth, Laura, Ertl, Miriam, Burdach, Stefan

“…Ewing sarcoma (ES), an osteogenic malignancy that mainly affects children and young adults, is characterized by early metastasis to lung and bone. Microarray…”
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Abstract 3106: The HoxD locus: Its contribution to the osteogenic phenotype and malignancy of Ewing sarcoma by Heyking, Kristina von, Roth, Laura, Ertl, Miriam, Burdach, Stefan, Richter, Günther H.

“…Ewing sarcoma (ES), an osteogenic malignancy that mainly affects children and young adults, is characterized by early metastasis to lung and bone. Microarray…”
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Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma by Richter, Günther H S, Hensel, Tim, Schmidt, Oxana, Saratov, Vadim, von Heyking, Kristina, Becker-Dettling, Fiona, Prexler, Carolin, Yen, Hsi-Yu, Steiger, Katja, Fulda, Simone, Dirksen, Uta, Weichert, Wilko, Wang, Shudong, Burdach, Stefan, Schäfer, Beat W

“…Previously, we used inhibitors blocking BET bromodomain binding proteins (BRDs) in Ewing sarcoma (EwS) and observed that long term treatment resulted in the…”
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The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma by von Heyking, Kristina, Roth, Laura, Ertl, Miriam, Schmidt, Oxana, Calzada-Wack, Julia, Neff, Frauke, Lawlor, Elizabeth R, Burdach, Stefan, Richter, Guenther Hs

“…Microarray analysis revealed genes of the posterior HOXD locus normally involved in bone formation to be over-expressed in primary Ewing sarcoma (ES). The…”
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The endochondral bone protein CHM 1 sustains an undifferentiated, invasive phenotype, promoting lung metastasis in Ewing sarcoma by von Heyking, Kristina, Calzada‐Wack, Julia, Göllner, Stefanie, Neff, Frauke, Schmidt, Oxana, Hensel, Tim, Schirmer, David, Fasan, Annette, Esposito, Irene, Müller‐Tidow, Carsten, Sorensen, Poul H., Burdach, Stefan, Richter, Günther H. S.

“…Ewing sarcomas ( ES ) are highly malignant, osteolytic bone or soft tissue tumors, which are characterized by EWS – ETS translocations and early metastasis to…”
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