Search Results - "Heydari, Tiam"

High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation-associated versus preneurulation-associated fate patterning by Tewary, Mukul, Dziedzicka, Dominika, Ostblom, Joel, Prochazka, Laura, Shakiba, Nika, Heydari, Tiam, Aguilar-Hidalgo, Daniel, Woodford, Curtis, Piccinini, Elia, Becerra-Alonso, David, Vickers, Alice, Louis, Blaise, Rahman, Nafees, Danovi, Davide, Geens, Mieke, Watt, Fiona M, Zandstra, Peter W

“…In vitro models of postimplantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report…”
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Inferring Gene Regulatory Networks and Predicting the Effect of Gene Perturbations via IQCELL by Heydari, Tiam, Zandstra, Peter W

“…IQCELL is a platform that infers Boolean gene regulatory networks from single-cell RNA sequencing data. Boolean networks can be simulated under normal and…”
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Development of a Virtual Cell Model to Predict Cell Response to Substrate Topography by Heydari, Tiam, Heidari, Maziar, Mashinchian, Omid, Wojcik, Michal, Xu, Ke, Dalby, Matthew John, Mahmoudi, Morteza, Ejtehadi, Mohammad Reza

“…Cells can sense and respond to changes in the topographical, chemical, and mechanical information in their environment. Engineered substrates are increasingly…”
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Naive pluripotent stem cell-based models capture FGF-dependent human hypoblast lineage specification by Dattani, Anish, Corujo-Simon, Elena, Radley, Arthur, Heydari, Tiam, Taheriabkenar, Yasaman, Carlisle, Francesca, Lin, Simeng, Liddle, Corin, Mill, Jonathan, Zandstra, Peter W, Nichols, Jennifer, Guo, Ge

“…The hypoblast is an essential extraembryonic tissue set aside within the inner cell mass in the blastocyst. Research with human embryos is challenging. Thus,…”
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Engineering of Mature Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Using Substrates with Multiscale Topography by Abadi, Parisa P. S. S., Garbern, Jessica C., Behzadi, Shahed, Hill, Michael J., Tresback, Jason S., Heydari, Tiam, Ejtehadi, Mohammad Reza, Ahmed, Nafis, Copley, Elizabeth, Aghaverdi, Haniyeh, Lee, Richard T., Farokhzad, Omid C., Mahmoudi, Morteza

“…Producing mature and functional cardiomyocytes (CMs) by in vitro differentiation of induced pluripotent stem cells (iPSCs) using only biochemical cues is…”
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Biomedical Applications: Engineering of Mature Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Using Substrates with Multiscale Topography (Adv. Funct. Mater. 19/2018) by Abadi, Parisa P. S. S., Garbern, Jessica C., Behzadi, Shahed, Hill, Michael J., Tresback, Jason S., Heydari, Tiam, Ejtehadi, Mohammad Reza, Ahmed, Nafis, Copley, Elizabeth, Aghaverdi, Haniyeh, Lee, Richard T., Farokhzad, Omid C., Mahmoudi, Morteza

“…Immaturity of cardiomyocytes derived from induced pluripotent stem cells is an important issue in the field of cell therapeutics. In article number 1707378,…”
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