Search Results - "Heyam, Alex"

Dissecting the roles of TRBP and PACT in double-stranded RNA recognition and processing of noncoding RNAs by Heyam, Alex, Lagos, Dimitris, Plevin, Michael

“…HIV TAR RNA‐binding protein (TRBP) and Protein Activator of PKR (PACT) are double‐stranded (ds) RNA‐binding proteins that participate in both small regulatory…”
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Nuclear Magnetic Resonance and Computational Study of trans-(μ2:η2,η2‑1,3-Butadiene)bis(trichloroplatinate(II)) by Silalahi, Imelda H, Heyam, Alex P, Goult, Christopher A, Aguiar, Pedro, Karadakov, Peter B, Bruce, Duncan W

“…The complex bis­(tetrabutylammonium) (trans-μ2:η2,η2-1,3-butadiene)­bis­(trichloroplatinate­(II)), identified from its X-ray single-crystal structure, is…”
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1H, 13C, 15N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei by Makraki, Eleni, Carneiro, Marta G., Heyam, Alex, Eiso, A. B., Siegal, Gregg, Hubbard, Roderick E.

“…β-glucosidases have received considerable attention due to their essential role in bioethanol production from lignocellulosic biomass. β-glucosidase can…”
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Correction to: 1H, 13C, 15N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei by Makraki, Eleni, Carneiro, Marta G., Heyam, Alex, AB, Eiso, Siegal, Gregg, Hubbard, Roderick E.

“…In the original publication of the article, the name of one of the authors is incorrect. The author's name is Eiso AB, but was modified to A. B. Eiso. The…”
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Conserved asymmetry underpins homodimerization of Dicer-associated double-stranded RNA-binding proteins by Heyam, Alex, Coupland, Claire E., Dégut, Clément, Haley, Ruth A., Baxter, Nicola J., Jakob, Leonhard, Aguiar, Pedro M., Meister, Gunter, Williamson, Michael P., Lagos, Dimitris, Plevin, Michael J.

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Silver–N-Heterocyclic Carbenes in π–Activation: Synergistic Effects between the Ligand Ring Size and the Anion by Frith, Abigail, Clarke, Aimee K., Heyam, Alex, Lynam, Jason M., Newman, Paul D., Unsworth, William P., Willans, Charlotte E.

“…A series of 12 silver­(I)–N-heterocyclic carbene (NHC) complexes were prepared featuring five- (both saturated and unsaturated backbone), six-, and…”
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Atomistic modelling and NMR studies reveal that gallium can target the ferric PQS uptake system in P. aeruginosa biofilms by Hills, Oliver J, Noble, Isaac O K, Heyam, Alex, Scott, Andrew J, Smith, James, Chappell, Helen F

“…Intravenous gallium nitrate therapy is a novel therapeutic strategy deployed to combat chronic biofilm infections in the lungs of cystic fibrosis (CF) patients…”
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A Reductive Aminase Switches to Imine Reductase Mode for a Bulky Amine Substrate by Gilio, Amelia K., Thorpe, Thomas W., Heyam, Alex, Petchey, Mark R., Pogrányi, Balázs, France, Scott P., Howard, Roger M., Karmilowicz, Michael J., Lewis, Russell, Turner, Nicholas, Grogan, Gideon

“…Imine reductases (IREDs) catalyze the asymmetric reduction of cyclic imines, but also in some cases the coupling of ketones and amines to form secondary amine…”
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Polyphosphinoborane Block Copolymer Synthesis Using Catalytic Reversible Chain‐Transfer Dehydropolymerization by Race, James J., Heyam, Alex, Wiebe, Matthew A., Diego‐Garcia Hernandez, J., Ellis, Charlotte E., Lei, Shixing, Manners, Ian, Weller, Andrew S.

“…An amphiphilic block copolymer of polyphosphinoborane has been prepared by a mechanism‐led strategy of the sequential catalytic dehydropolymerization of…”
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Fragment-derived modulators of an industrial β-glucosidase by Makraki, Eleni, Darby, John F, Carneiro, Marta G, Firth, James D, Heyam, Alex, Ab, Eiso, O'Brien, Peter, Siegal, Gregg, Hubbard, Roderick E

“…A fragment screen of a library of 560 commercially available fragments using a kinetic assay identified a small molecule that increased the activity of the…”
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Ortho -aryl substituted DPEphos ligands: rhodium complexes featuring C–H anagostic interactions and B–H agostic bonds by Race, James J., Burnage, Arron L., Boyd, Timothy M., Heyam, Alex, Martínez-Martínez, Antonio J., Macgregor, Stuart A., Weller, Andrew S.

“…The synthesis of new Schrock–Osborn Rh( i ) pre-catalysts with ortho -substituted DPEphos ligands, [Rh(DPEphos-R)(NBD)][BAr F 4 ] [R = Me, OMe, i Pr; Ar F =…”
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S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells by Warner, Matthew J, Bridge, Katherine S, Hewitson, James P, Hodgkinson, Michael R, Heyam, Alex, Massa, Bailey C, Haslam, Jessica C, Chatzifrangkeskou, Maria, Evans, Gareth J O, Plevin, Michael J, Sharp, Tyson V, Lagos, Dimitris

“…MicroRNAs (miRNAs) are short non-coding RNAs that silence mRNAs. They are generated following transcription and cleavage by the DROSHA/DGCR8 and…”
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Conserved asymmetry underpins homodimerization of Dicer-associated double-stranded RNA-binding proteins by Heyam, Alex, Coupland, Claire E, Dégut, Clément, Haley, Ruth A, Baxter, Nicola J, Jakob, Leonhard, Aguiar, Pedro M, Meister, Gunter, Williamson, Michael P, Lagos, Dimitris, Plevin, Michael J

“…Double-stranded RNA-binding domains (dsRBDs) are commonly found in modular proteins that interact with RNA. Two varieties of dsRBD exist: canonical Type A…”
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Biophysical studies of asymmetric homodimerisation of the microrna biogenesis cofactors pact and trbp by Heyam, Alex

“…Processing of precursor microRNAs by Dicer is a key step in microRNA biogenesis. This process is assisted by the homologous proteins PACT and TRBP, which bind…”
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1 H, 13 C, 15 N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei by Makraki, Eleni, Carneiro, Marta G, Heyam, Alex, Eiso, A B, Siegal, Gregg, Hubbard, Roderick E

“…β-glucosidases have received considerable attention due to their essential role in bioethanol production from lignocellulosic biomass. β-glucosidase can…”
Get full text

Polyphosphinoborane Block Copolymer Synthesis Using Catalytic Reversible Chain‐Transfer Dehydropolymerization by Race, James J., Heyam, Alex, Wiebe, Matthew A., Diego‐Garcia Hernandez, J., Ellis, Charlotte E., Lei, Shixing, Manners, Ian, Weller, Andrew S.

“…An amphiphilic block copolymer of polyphosphinoborane has been prepared by a mechanism‐led strategy of the sequential catalytic dehydropolymerization of…”
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aryl substituted DPEphos ligands: rhodium complexes featuring C-H anagostic interactions and B-H agostic bonds by Race, James J, Burnage, Arron L, Boyd, Timothy M, Heyam, Alex, Martínez-Martínez, Antonio J, Macgregor, Stuart A, Weller, Andrew S

“…The synthesis of new Schrock-Osborn Rh( i ) pre-catalysts with ortho -substituted DPEphos ligands, [Rh(DPEphos-R)(NBD)][BAr F 4 ] [R = Me, OMe, i Pr; Ar F =…”
Get full text