Search Results - "Hexum, Melinda K"
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Clinical‐Scale Derivation of Natural Killer Cells From Human Pluripotent Stem Cells for Cancer Therapy
Published in Stem cells translational medicine (01-04-2013)“…This study used a two‐stage culture system to efficiently produce natural killer (NK) cells from human embryonic stem cells (hESCs) and induced pluripotent…”
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Human Pluripotent Stem Cells Produce Natural Killer Cells That Mediate Anti-HIV-1 Activity by Utilizing Diverse Cellular Mechanisms
Published in Journal of Virology (01-01-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Targeting tumor-initiating cancer cells with dCD133KDEL shows impressive tumor reductions in a xenotransplant model of human head and neck cancer
Published in Molecular cancer therapeutics (01-10-2011)“…A novel anticancer agent was constructed by fusing a gene encoding the scFV that targets both glycosylated and unglycosylated forms of CD133 to a gene fragment…”
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Bioluminescent Imaging Demonstrates That Transplanted Human Embryonic Stem Cell‐Derived CD34+ Cells Preferentially Develop into Endothelial Cells
Published in Stem cells (Dayton, Ohio) (01-11-2009)“…Human embryonic stem cells (hESCs) provide an important resource for novel regenerative medicine therapies and have been used to derive diverse cell…”
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Functional assessment of hematopoietic niche cells derived from human embryonic stem cells
Published in Stem cells and development (15-06-2014)“…To evaluate hematopoietic niche cell populations isolated from human embryonic stem cells (hESCs), we tested the ability of hESC-derived stromal lines to…”
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In vivo evaluation of putative hematopoietic stem cells derived from human pluripotent stem cells
Published in Methods in molecular biology (Clifton, N.J.) (2011)“…Efficient derivation and isolation of hematopoietic stem cells (HSCs) from human pluripotent stem cell (hPSC) populations remains a major goal in the field of…”
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Effective Development of Hematopoietic Niche Cells From hESCs: hESC-Derived Stromal Cells Support LTC-ICs Better Than Bone Marrow-Derived Stromal Cells
Published in Blood (18-11-2011)“…Abstract 4804 Quantification of putative hematopoietic stem cells (HSCs) in human bone marrow or cord blood is typically assessed by its potential to mediate…”
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Differentiation of Human Natural Killer Cells From Pluripotent Stem Cells In a Feeder Free System Amenable to Clinical Translation
Published in Blood (19-11-2010)“…Abstract 107 Human natural killer (NK) cells are an attractive source of lymphocytes for adoptive immunotherapy. Although our understanding of natural killer…”
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Osteoclasts From Human Embryonic Stem Cell-Derived Hematopoietic Progenitors Support Development of An in Vitro Niche Microenvironment
Published in Blood (20-11-2009)“…Abstract 2517 Poster Board II-494 Osteoclasts are bone resorbing cells located in the bone marrow that play a key role in hematopoiesis and formation of the…”
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Human Embryonic Stem Cell-Derived CD34+ Cells Preferentially Develop into Endothelial Cells When Transplanted into Neonatal Immunodeficient Mice
Published in Blood (16-11-2008)“…Selection for CD34+ cells from human bone marrow, umbilical cord blood and mobilized peripheral blood cells has been used to enrich for putative hematopoietic…”
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Bioluminescent imaging demonstrates transplanted human embryonic stem cell-derived CD34+ cells preferentially develop into endothelial cells
Published in Stem cells (Dayton, Ohio) (01-11-2009)“…Human embryonic stem cells (hESCs) provide an important resource for novel regenerative medicine therapies and have been used to derive diverse cell…”
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