Search Results - "Hewitt, Zöe"

Efficient Differentiation of Hepatocytes from Human Embryonic Stem Cells Exhibiting Markers Recapitulating Liver Development In Vivo by Hay, David C., Zhao, Debiao, Fletcher, Judy, Hewitt, Zoë A., McLean, Doris, Urruticoechea‐Uriguen, Alai, Black, James R., Elcombe, Cliff, Ross, James A., Wolf, Roland, Cui, Wei

“…The potential to differentiate human embryonic stem cells (hESCs) in vitro to provide an unlimited source of human hepatocytes for use in biomedical research,…”
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Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions by Thompson, Oliver, von Meyenn, Ferdinand, Hewitt, Zoe, Alexander, John, Wood, Andrew, Weightman, Richard, Gregory, Sian, Krueger, Felix, Andrews, Simon, Barbaric, Ivana, Gokhale, Paul J., Moore, Harry D., Reik, Wolf, Milo, Marta, Nik-Zainal, Serena, Yusa, Kosuke, Andrews, Peter W.

“…The occurrence of repetitive genomic changes that provide a selective growth advantage in pluripotent stem cells is of concern for their clinical application…”
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The Molecular Karyotype of 25 Clinical-Grade Human Embryonic Stem Cell Lines by Canham, Maurice A., Van Deusen, Amy, Brison, Daniel R., De Sousa, Paul A., Downie, Janet, Devito, Liani, Hewitt, Zoe A., Ilic, Dusko, Kimber, Susan J., Moore, Harry D., Murray, Helen, Kunath, Tilo

“…The application of human embryonic stem cell (hESC) derivatives to regenerative medicine is now becoming a reality. Although the vast majority of hESC lines…”
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GMP-grade neural progenitor derivation and differentiation from clinical-grade human embryonic stem cells by Vitillo, Loriana, Durance, Catherine, Hewitt, Zoe, Moore, Harry, Smith, Austin, Vallier, Ludovic

“…A major challenge for the clinical use of human pluripotent stem cells is the development of safe, robust and controlled differentiation protocols. Adaptation…”
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Retinoic Acid Accelerates the Specification of Enteric Neural Progenitors from In-Vitro-Derived Neural Crest by Frith, Thomas J.R., Gogolou, Antigoni, Hackland, James O.S., Hewitt, Zoe A., Moore, Harry D., Barbaric, Ivana, Thapar, Nikhil, Burns, Alan J., Andrews, Peter W., Tsakiridis, Anestis, McCann, Conor J.

“…The enteric nervous system (ENS) is derived primarily from the vagal neural crest, a migratory multipotent cell population emerging from the dorsal neural tube…”
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Autophagic response to cell culture stress in pluripotent stem cells by Gregory, Siân, Swamy, Sushma, Hewitt, Zoe, Wood, Andrew, Weightman, Richard, Moore, Harry

“…Autophagy is an important conserved cellular process, both constitutively as a recycling pathway for long lived proteins and as an upregulated stress response…”
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Comparability: manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform Pluripotent Stem Cell Platform Workshop, Trinity Hall, Cambridge, 14-15 September 2015 by Williams, David J, Archer, Richard, Archibald, Peter, Bantounas, Ioannis, Baptista, Ricardo, Barker, Roger, Barry, Jacqueline, Bietrix, Florence, Blair, Nicholas, Braybrook, Julian, Campbell, Jonathan, Canham, Maurice, Chandra, Amit, Foldes, Gabor, Gilmanshin, Rudy, Girard, Mathilde, Gorjup, Erwin, Hewitt, Zöe, Hourd, Paul, Hyllner, Johan, Jesson, Helen, Kee, Jasmin, Kerby, Julie, Kotsopoulou, Nina, Kowalski, Stanley, Leidel, Chris, Marshall, Damian, Masi, Louis, McCall, Mark, McCann, Conor, Medcalf, Nicholas, Moore, Harry, Ozawa, Hiroki, Pan, David, Parmar, Malin, Plant, Anne L, Reinwald, Yvonne, Sebastian, Sujith, Stacey, Glyn, Thomas, Robert J, Thomas, Dave, Thurman-Newell, Jamie, Turner, Marc, Vitillo, Loriana, Wall, Ivan, Wilson, Alison, Wolfrum, Jacqueline, Yang, Ying, Zimmerman, Heiko

“…This paper summarizes the proceedings of a workshop held at Trinity Hall, Cambridge to discuss comparability and includes additional information and references…”
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The isochromosome 20q abnormality of pluripotent cells interrupts germ layer differentiation by Vitillo, Loriana, Anjum, Fabiha, Hewitt, Zoe, Stavish, Dylan, Laing, Owen, Baker, Duncan, Barbaric, Ivana, Coffey, Pete

“…Chromosome 20 abnormalities are some of the most frequent genomic changes acquired by human pluripotent stem cell (hPSC) cultures worldwide. Yet their effects…”
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Nucleosides Rescue Replication-Mediated Genome Instability of Human Pluripotent Stem Cells by Halliwell, Jason A., Frith, Thomas J.R., Laing, Owen, Price, Christopher J., Bower, Oliver J., Stavish, Dylan, Gokhale, Paul J., Hewitt, Zoe, El-Khamisy, Sherif F., Barbaric, Ivana, Andrews, Peter W.

“…Human pluripotent stem cells (PSCs) are subject to the appearance of recurrent genetic variants on prolonged culture. We have now found that, compared with…”
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A decade of progress: Achievements and future challenges for regenerative medicine research in the United Kingdom by Curle, Annabel J., Barnes, Josephine L., Owen, Robert, Barker, Roger A., El Haj, Alicia, Forbes, Stuart J., Ghevaert, Cedric, Oreffo, Richard OC, Rose, Felicity RAJ, Stevens, Molly M., Hewitt, Zoe

“…The final United Kingdom Regenerative Medicine Platform (UKRMP) conference held in Edinburgh's iconic McEwan Hall between 8th and November 10, 2023 saw a…”
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Innovative Thinking.(television and movie production adapting to COVID-19) by Hewitt, Zoe

“…A process called permitting allows nonunion crew to work on a production, but only once all available union members have been dispatched. Grappling with the…”
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Designers Face Big Cast Challenges Onscreen.(2020 Artisans Preview) by Hewitt, Zoe

“…[...]costume designer Susan Lyall's work on director Aaron Sorkin's "The Trial of the Chicago 7" involved real-life activists following protests at the 1968…”
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Distributed automated manufacturing of pluripotent stem cell products by Shariatzadeh, Maryam, Chandra, Amit, Wilson, Samantha L, McCall, Mark J, Morizur, Lise, Lesueur, Léa, Chose, Olivier, Gepp, Michael M., Schulz, André, Neubauer, Julia C., Zimmermann, Heiko, Abranches, Elsa, Man, Jennifer, O’Shea, Orla, Stacey, Glyn, Hewitt, Zoe, Williams, David J

“…Establishing how to effectively manufacture cell therapies is an industry-level problem. Decentralised manufacturing is of increasing importance, and its…”
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In Vivo Tumorigenicity of the 20q11.21 Amplicon in an Engraftment Model of hPSCs and Differentiated Liver Cells by Pridgeon, Chris S, Forootan, Shiva Seyed, Zhang, Fang, Harper, Nicholas, Palmer, Daniel, Weightmann, Richard, Gregory, Sian, Hewitt, Zoe, Baker, Duncan, Halliwell, Jason, Moore, Harry, Ricci, Emanuele, Andrews, Peter W, Poptani, Harish, Hay, David C, Park, B Kevin, Goldring, Chris E P

“…Human pluripotent stem cells (hPSCs) are a promising source of somatic cells for clinical applications and disease modelling. However, during culture they…”
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Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform by Stacey, Glyn N, Andrews, Peter W, Barbaric, Ivana, Boiers, Charlotta, Chandra, Amit, Cossu, Giulio, Csontos, Lynn, Frith, Thomas JR, Halliwell, Jason A, Hewitt, Zoe, McCall, Mark, Moore, Harry D, Parmar, Malin, Panico, M Beatrice, Pisupati, Venkat, Shichkin, Valentin P, Stacey, Alison R, Tedesco, Francesco S, Thompson, Oliver, Wagey, Ravenska

“…Human stem cells have the potential to transform medicine. However, hurdles remain to ensure that manufacturing processes produce safe and effective products…”
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Ablation of Undifferentiated Human Embryonic Stem Cells: Exploiting Innate Immunity Against the Gal α1‐3Galβ1‐4GlcNAc‐R (α‐Gal) Epitope by Hewitt, Zoe, Priddle, Helen, Thomson, Alison J., Wojtacha, Davina, McWhir, Jim

“…Although undifferentiated human embryonic stem cells (hESCs) are tumorigenic, this capacity is lost after differentiation, and hESCs are being widely…”
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Human embryonic stem cells passaged using enzymatic methods retain a normal karyotype and express CD30 by Thomson, Alison, Wojtacha, Davina, Hewitt, Zoë, Priddle, Helen, Sottile, Virginie, Di Domenico, Alex, Fletcher, Judy, Waterfall, Martin, Corrales, Néstor López, Ansell, Ray, McWhir, Jim

“…Human embryonic stem cells (hESCs) are thought to be susceptible to chromosomal rearrangements as a consequence of single cell dissociation. Compared in this…”
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Ablation of Undifferentiated Human Embryonic Stem Cells: Exploiting Innate Immunity Against the Gal alpha 1-3Gal{beta}1-4GlcNAc-R ( alpha -Gal) Epitope by Hewitt, Zoe, Priddle, Helen, Thomson, Alison J, Wojtacha, Davina, McWhir, Jim

“…Although undifferentiated human embryonic stem cells (hESCs) are tumorigenic, this capacity is lost after differentiation, and hESCs are being widely…”
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Ablation of undifferentiated human embryonic stem cells: exploiting innate immunity against the Gal alpha1-3Galbeta1-4GlcNAc-R (alpha-Gal) epitope by Hewitt, Zoe, Priddle, Helen, Thomson, Alison J, Wojtacha, Davina, McWhir, Jim

“…Although undifferentiated human embryonic stem cells (hESCs) are tumorigenic, this capacity is lost after differentiation, and hESCs are being widely…”
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Control differentiation of embryonic stem cell to specific lineages by Zhao, Debiao, Hay, David, Fletcher, Judy, Hewitt, Zoe, McLean, Doris, Black, James, Urruticoechea-Uriguen, Alai, Elcombe, Cliff, Ross, James, Wolf, Roland, Cui, Wei

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