Search Results - "Hewitt, Rachael N."
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HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia
Published in Genes & development (15-12-2014)“…Cellular senescence is a stable proliferation arrest that suppresses tumorigenesis. Cellular senescence and associated tumor suppression depend on control of…”
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Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest
Published in Cell reports (Cambridge) (01-09-2015)“…Oncogene-induced senescence (OIS) is a tumor suppression mechanism that blocks cell proliferation in response to oncogenic signaling. OIS is frequently…”
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Wnt signaling potentiates nevogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (01-10-2013)“…Cellular senescence is a stable proliferation arrest associated with an altered secretory pathway (senescence-associated secretory phenotype). Cellular…”
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Biomimetic microtopography to enhance osteogenesis in vitro
Published in Acta biomaterialia (01-07-2011)“…Biomimicry is being used in the next generation of biomaterials. Tuning material surface features such as chemistry, stiffness and topography allow the control…”
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