Search Results - "Hewitt, K. N"
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1
Estrogen—the Good, the Bad, and the Unexpected
Published in Endocrine reviews (01-05-2005)Get full text
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2
Sex differences in emotionality in C3H/HeH mice, with hypogonadal mutant to distinguish activational effects of gonadal hormones
Published in Physiology & behavior (08-01-2009)“…Abstract The C3H/HeH mouse strain has a mutant hypogonadal (hpg) variant, providing an animal model to examine the activational effects of sex hormones because…”
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3
Cholesterol feeding prevents adiposity in the obese female aromatase knockout (ArKO) mouse
Published in Hormone and metabolic research (01-01-2005)“…The aromatase (ArKO) knockout mouse develops obesity marked by increased gonadal fat depots. This obesity is characterized by pronounced hypertrophy and…”
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4
Aromatase-Deficient (ArKO) Mice Have a Phenotype of Increased Adiposity
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-2000)“…The aromatase-knockout (ArKO) mouse provides a useful model to examine the role that estrogens play in development and homeostasis in mammals. Lacking a…”
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5
Serotonin 2C receptor agonists and the behavioural satiety sequence in mice
Published in Pharmacology, biochemistry and behavior (01-04-2002)“…The studies reported here examined the role of the 5-hydroxytryptamine (5-HT) 2C receptor subtype in the control of ingestive behaviour in mice. Behavioural…”
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6
Aromatase-deficient (ArKO) mice accumulate excess adipose tissue
Published in Journal of steroid biochemistry and molecular biology (01-12-2001)“…Aromatase is the enzyme which catalyses the conversion of C 19 steroids into C 18 estrogens. We have generated a mouse model wherein the Cyp19 gene, which…”
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7
Immunocytochemical localization of Fos protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy
Published in International journal of cancer (22-08-1995)“…The nuclear transcription factor Fos is inducible by both steroid hormones and peptide growth factors. It thus forms a potential point of interaction between…”
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Minireview: Hexose-6-Phosphate Dehydrogenase and Redox Control of 11β-Hydroxysteroid Dehydrogenase Type 1 Activity
Published in Endocrinology (Philadelphia) (01-06-2005)“…Hexose-6-phosphate dehydrogenase (H6PDH) is a microsomal enzyme that is able to catalyze the first two reactions of an endoluminal pentose phosphate pathway,…”
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9
Estrogen Replacement Reverses the Hepatic Steatosis Phenotype in the Male Aromatase Knockout Mouse
Published in Endocrinology (Philadelphia) (01-04-2004)“…The aromatase knockout (ArKO) mouse cannot synthesize endogenous estrogens due to a disruption to the Cyp19 gene. Previously we have shown both male and female…”
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10
Estrogen- : the good, the bad, and the unexpected: Recent progress in hormone research
Published in Endocrine reviews (2005)Get full text
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11
The Aromatase Knockout Mouse Presents with a Sexually Dimorphic Disruption to Cholesterol Homeostasis
Published in Endocrinology (Philadelphia) (01-09-2003)“…The aromatase knockout (ArKO) mouse cannot synthesize endogenous estrogens due to disruption of the Cyp19 gene. We have shown previously, that ArKO mice…”
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Behavioural and pharmacological magnetic resonance imaging assessment of the effects of methylphenidate in a potential new rat model of attention deficit hyperactivity disorder
Published in Psychopharmacology (01-08-2005)“…The psychomotor stimulant methylphenidate is used in the treatment of attention deficit hyperactivity disorder (ADHD). Whereas the mechanism is not fully…”
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