Search Results - "Hewetson, J F"

Detection of ricin by colorimetric and chemiluminescence ELISA by Poli, M A, Rivera, V R, Hewetson, J F, Merrill, G A

“…A highly sensitive and specific ELISA was developed to detect ricin in biological fluids. The assay utilizes an affinity-purified goat polyclonal antibody to…”
Get more information

Distribution and elimination of brevetoxin PbTx-3 in rats by Poli, M A, Templeton, C B, Thompson, W L, Hewetson, J F

“…After i.v. administration, [3H]PbTx-3 was rapidly cleared from the blood; less than 10% remained after 1 min. Within 30 min, radiolabel distributed to skeletal…”
Get more information

Polyclonal anti-idiotypes induce antibody responses protective against ricin cytotoxicity by CHANH, T. C, HEWETSON, J. F

“…Protein G-purified goat anti-ricin IgG, previously demonstrated to protect against ricin toxicity in vitro and in vivo, was used to raise BALB/c mouse and New…”
Get full text

Protection of mice from inhaled ricin by vaccination with ricin or by passive treatment with heterologous antibody by Hewetson, J F, Rivera, V R, Creasia, D A, Lemley, P V, Rippy, M K, Poli, M A

“…Mice were vaccinated subcutaneously with 25 micrograms kg-1 of ricin in the presence of Freund's complete adjuvant or Ribi adjuvant, followed by a boost 14…”
Get more information

Monoclonal anti-idiotype induces protection against the cytotoxicity of the trichothecene mycotoxin T-2 by Chanh, TC, Rappocciolo, G, Hewetson, JF

“…An IgG1 mAb, designated HD11, specific for the trichothecene mycotoxin T-2 and capable of neutralizing its cytotoxicity was used to generate a syngeneic…”
Get full text

A rapid, large scale purification procedure for gibbon interleukin 2 by Henderson, LE, Hewetson, JF, Hopkins, RF, 3d, Sowder, RC, Neubauer, RH, Rabin, H

“…Interleukin 2 (IL 2) was purified from the conditioned medium of a gibbon T cell line, MLA144, which releases IL 2 constitutively. The IL 2 was obtained free…”
Get full text

Anti-idiotypic antibodies against a monoclonal antibody specific for the trichothecene mycotoxin T-2 by Chanh, T C, Huot, R I, Schick, M R, Hewetson, J F

“…A BALB/c murine monoclonal antibody against the trichothecene mycotoxin T-2 was generated. The antibody, designated HD11, specifically bound T-2 mycotoxin. The…”
Get more information

Validation of ELISA for the determination of anti-ricin immunoglobulin G concentration in mouse sera by Lindsey, Changhong Y., Pace-Templeton, Judith G., Millard, Charles B., Wannemacher, Robert W., Hewetson, John F.

“…An enzyme-linked immunosorbent assay (ELISA) for the determination of anti-ricin immunoglobulin G (IgG) concentration in mouse sera was systematically…”
Get full text

A Practical and Quantitative Microtest for Determination of Neutralizing Antibodies against Epstein-Barr Virus by Rocchi, G, Hewetson, J. F

“…The Virus Laboratories at The Children's Hospital of Philadelphia and the School of Medicine University of Pennsylvania Philadelphia, Pennsylvania 19146,…”
Get full text

Structure/function studies of T-2 mycotoxin with a monoclonal antibody by Chanh, T C, Hewetson, J F

“…A BALB/C murine monoclonal antibody (mAb) specific for the trichothecene mycotoxin T-2 was previously generated. The anti-T-2 antibody, designated HD11, can…”
Get more information

Protection against ricin intoxication in vivo by anti-idiotype vaccination by Chanh, Tran C., Hewetson, John F.

“…A BALB c murine anti-ricin monoclonal antibody (mAb BG11-G2, IgG 1κ), was recently isolated and shown to passively protect syngeneic mice against ricin…”
Get full text

Surface Marker Characteristics and Epstein-Barr Virus Studies of Two Established North American Burkitt's Lymphoma Cell Lines by Epstein, Alan L., Henle, Werner, Henle, Gertrude, Hewetson, John F., Kaplan, Henry S.

“…Tumor cell lines have been established in continuous culture from two North American Burkitt's lymphomas. The SU-AmB-1 line, derived from a patient with low…”
Get full text

Development of antibodies reactive in antibody-dependent cellular cytotoxicity in infectious mononucleosis by Hewetson, J F, Böcker, J F, Sereni, P, Rapp, C E, Henle, W

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Neutralizing Antibodies to Epstein-Barr Virus in Healthy Populations and Patients with Infectious Mononucleosis by Hewetson, John F., Rocchi, Giovanni, Henle, Werner, Henle, Gertrude

“…Sera from healthy donors and individuals with primary Epstein-Barr virus (EBV) infections were titrated for EBV-neutralizing antibodies, and the results were…”
Get full text

Detection and quantitation of T-2 mycotoxin in rat organs by radioimmunoassay by Hewetson, J F, Pace, J G, Beheler, J E

“…A standard radioimmunoassay was compared with radiochromatography for the ability to detect unlabeled T-2 mycotoxin in organs from exposed animals. When 10% of…”
Get more information

Infection of rhesus monkeys and chimpanzees with Epstein-Barr virus by Levine, P H, Leiseca, S A, Hewetson, J F, Traul, K A, Andrese, A P, Granlund, D J, Fabrizio, P, Stevens, D A

“…Seventy-two nonhuman primates were entered into a long-term study to evaluate the pathogenicity of Epstein-Barr virus (EBV). Infectious virus was inoculated…”
Get full text

Monoclonal antibody prophylaxis against the in vivo toxicity of ricin in mice by Chanh, T C, Romanowski, M J, Hewetson, J F

“…A BALB/c murine IgG1 monoclonal antibody, designated BG11-G2, specific for ricin was generated. BG11-G2 antibody did not bind to either purified ricin chain A…”
Get more information

Polyclonal anti-idiotypes induce specific anti-saxitoxin antibody responses by Chanh, T C, Hewetson, J F

“…Polyclonal BALB/C mouse and New Zealand White rabbit anti-idiotypic antibodies were raised by immunization with a protein G-purified burro anti-saxitoxin IgG…”
Get more information

Reversal of saxitoxin-induced cardiorespiratory failure by a burro-raised alpha-STX antibody and oxygen therapy by Benton, B J, Rivera, V R, Hewetson, J F, Chang, F C

“…Reversal of saxitoxin (STX; 10 micrograms/kg, ip) induced cardiorespiratory effects by oxygen ventilation and burro-raised alpha-STX antitoxin (60 mg/kg, i.v.)…”
Get more information

Anti-idiotype-based vaccines against biological toxins by Chanh, T C, Siwak, E B, Hewetson, J F

“…Biological toxins produced by living organisms represent one of the major sources of contamination of stored grain and agricultural products, and other food…”
Get more information