Search Results - "Heveran, Chelsea M"

The flying insect thoracic cuticle is heterogenous in structure and in thickness-dependent modulus gradation by Casey, Cailin, Yager, Claire, Jankauski, Mark, Heveran, Chelsea M.

“…The thorax is a specialized structure central to insect flight. In the thorax, flight muscles are surrounded by a thin layer of cuticle. The structure,…”
Get full text

Engineered Ureolytic Microorganisms Can Tailor the Morphology and Nanomechanical Properties of Microbial-Precipitated Calcium Carbonate by Heveran, Chelsea M., Liang, Liya, Nagarajan, Aparna, Hubler, Mija H., Gill, Ryan, Cameron, Jeffrey C., Cook, Sherri M., Srubar, Wil V.

“…We demonstrate for the first time that the morphology and nanomechanical properties of calcium carbonate (CaCO 3 ) can be tailored by modulating the…”
Get full text

Multi-Scale Mechanical Behavior of the Li3PS4 Solid-Phase Electrolyte by Baranowski, Lauryn L, Heveran, Chelsea M, Ferguson, Virginia L, Stoldt, Conrad R

“…The need for smaller, lighter, and longer lasting rechargeable batteries is projected to increase rapidly in the coming years because of high demand for…”
Get full text

Determination of the True Lateral Grain Size in Organic–Inorganic Halide Perovskite Thin Films by MacDonald, Gordon A, Heveran, Chelsea M, Yang, Mengjin, Moore, David, Zhu, Kai, Ferguson, Virginia L, Killgore, Jason P, DelRio, Frank W

“…In this letter, methylammonium lead iodide (MAPbI3) thin films were examined via piezoresponse force microscopy (PFM) and nanoindentation (NI) to determine if…”
Get full text

Moderate chronic kidney disease impairs bone quality in C57Bl/6J mice by Heveran, Chelsea M, Ortega, Alicia M, Cureton, Andrew, Clark, Ryan, Livingston, Eric W, Bateman, Ted A, Levi, Moshe, King, Karen B, Ferguson, Virginia L

“…Abstract Chronic kidney disease (CKD) increases bone fracture risk. While the causes of bone fragility in CKD are not clear, the disrupted mineral homeostasis…”
Get full text

The Cortical Bone Metabolome of C57BL/6J Mice Is Sexually Dimorphic by Welhaven, Hope D., Vahidi, Ghazal, Walk, Seth T., Bothner, Brian, Martin, Stephen A., Heveran, Chelsea M., June, Ronald K.

“…ABSTRACT Cortical bone quality, which is sexually dimorphic, depends on bone turnover and therefore on the activities of remodeling bone cells. However, sex…”
Get full text

Ice-Binding Protein from Shewanella frigidimarinas Inhibits Ice Crystal Growth in Highly Alkaline Solutions by Delesky, Elizabeth A, Frazier, Shane D, Wallat, Jaqueline D, Bannister, Kendra L, Heveran, Chelsea M, Srubar, 3rd, Wil V

“…The ability of a natural ice-binding protein from (SfIBP) to inhibit ice crystal growth in highly alkaline solutions with increasing pH and ionic strength was…”
Get full text

Perilacunar bone tissue exhibits sub-micrometer modulus gradation which depends on the recency of osteocyte bone formation in both young adult and early-old-age female C57Bl/6 mice by Rux, Caleb J., Vahidi, Ghazal, Darabi, Amir, Cox, Lewis M., Heveran, Chelsea M.

“…Osteocytes resorb and replace bone local to the lacunar-canalicular system (LCS). However, whether osteocyte remodeling impacts bone quality adjacent to the…”
Get full text

A new open-source tool for measuring 3D osteocyte lacunar geometries from confocal laser scanning microscopy reveals age-related changes to lacunar size and shape in cortical mouse bone by Heveran, Chelsea M., Rauff, Adam, King, Karen B., Carpenter, R. Dana, Ferguson, Virginia L.

“…Osteocytes can participate in systemic mineral homeostasis through perilacunar maintenance and remodeling, where changes to osteocyte lacunar morphology may…”
Get full text

Development and analytical validation of a finite element model of fluid transport through osteochondral tissue by Hislop, Brady D., Heveran, Chelsea M., June, Ronald K.

“…Fluid transport is critical to joint health. In this study we evaluate an unexplored component of joint fluid transport –fluid transport between cartilage and…”
Get full text

Aging alters the subchondral bone response 7 days after noninvasive traumatic joint injury in C57BL/6JN mice by Dauenhauer, Lexia A., Hislop, Brady D., Brahmachary, Priyanka, Devine, Connor, Gibbs, Dustin, June, Ronald K., Heveran, Chelsea M.

“…Posttraumatic osteoarthritis (PTOA) commonly develops following anterior cruciate ligament (ACL) injuries, affecting around 50% of individuals within 10–20…”
Get full text

Osteochondral fluid transport in an ex vivo system by Hislop, Brady David, Mercer, Ara K., Whitley, Alexandria G., Myers, Erik P., Mackin, Marie, Heveran, Chelsea M., June, Ronald K.

“…Alterations to bone-to-cartilage fluid transport may contribute to the development of osteoarthritis (OA). Larger biological molecules in bone may transport…”
Get full text

Germ‐Free C57BL/6 Mice Have Increased Bone Mass and Altered Matrix Properties but Not Decreased Bone Fracture Resistance by Vahidi, Ghazal, Moody, Maya, Welhaven, Hope D., Davidson, Leah, Rezaee, Taraneh, Behzad, Ramina, Karim, Lamya, Roggenbeck, Barbara A., Walk, Seth T., Martin, Stephen A., June, Ronald K., Heveran, Chelsea M.

“…ABSTRACT The gut microbiome impacts bone mass, which implies a disruption to bone homeostasis. However, it is not yet clear how the gut microbiome affects the…”
Get full text

Chronic kidney disease and aging differentially diminish bone material and microarchitecture in C57Bl/6 mice by Heveran, Chelsea M., Schurman, Charles A., Acevedo, Claire, Livingston, Eric W., Howe, Danielle, Schaible, Eric G., Hunt, Heather B., Rauff, Adam, Donnelly, Eve, Carpenter, R. Dana, Levi, Moshe, Lau, Anthony G., Bateman, Ted A., Alliston, Tamara, King, Karen B., Ferguson, Virginia L.

“…Chronic kidney disease (CKD) is a common disease of aging and increases fracture risk over advanced age alone. Aging and CKD differently impair bone turnover…”
Get full text

Indentation mapping revealed poroelastic, but not viscoelastic, properties spanning native zonal articular cartilage by Wahlquist, Joseph A., DelRio, Frank W., Randolph, Mark A., Aziz, Aaron H., Heveran, Chelsea M., Bryant, Stephanie J., Neu, Corey P., Ferguson, Virginia L.

“…[Display omitted] Osteoarthrosis is a debilitating disease affecting millions, yet engineering materials for cartilage regeneration has proven difficult…”
Get full text

Sex differences in the effect of diet, obesity, and exercise on bone quality and fracture toughness by Sherk, Vanessa D., Heveran, Chelsea M., Foright, Rebecca M., Johnson, Ginger C., Presby, David M., Ferguson, Virginia L., MacLean, Paul S.

“…Bone fragility and obesity are both diseases that are multifactorial in etiology and pathology. The contributing role of high fat diet (HFD) versus energy…”
Get full text

An Autologous Cartilage Tissue Implant NeoCart for Treatment of Grade III Chondral Injury to the Distal Femur: Prospective Clinical Safety Trial at 2 Years by Crawford, Dennis C., Heveran, Chelsea M., Cannon, W. Dilworth, Foo, Li Foong, Potter, Hollis G.

“…Background The healing potential of damaged articular cartilage is limited. The NeoCart is a tissue-engineered collagen matrix seeded with autogenous…”
Get full text

Simulation of stresses in TBC–EBC coating systems for ceramic components in gas turbines by Heveran, Chelsea M., Xu, JiaPeng, Sarin, Vinod K., Basu, Soumendra N.

“…Thermal barrier coatings (TBCs) and environmental barrier coatings (EBCs) improve the efficiency and durability of turbine blades. Plasma-sprayed…”
Get full text

Rapamycin does not alter bone microarchitecture or material properties quality in young-adult and aged female C57BL/6 mice by Devine, Connor C, Brown, Kenna C, Paton, Kat O, Heveran, Chelsea M, Martin, Stephen A

“…Advancing age is the strongest risk factor for osteoporosis and skeletal fragility. Rapamycin is an FDA-approved immunosuppressant that inhibits the…”
Get full text

Multi-Scale Mechanical Behavior of the Li 3 PS 4 Solid-Phase Electrolyte by Baranowski, Lauryn L, Heveran, Chelsea M, Ferguson, Virginia L, Stoldt, Conrad R

“…The need for smaller, lighter, and longer lasting rechargeable batteries is projected to increase rapidly in the coming years because of high demand for…”
Get full text