Search Results - "Hevenor, Laura"

Discovery of First-in-Class Small Molecule Inhibitors of the IRF4-PU.1/Spi-B Interaction by Agius, Mike P., Hevenor, Laura, Payne, N Connor, Mazitschek, Ralph, Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Qi, Jun, Ghobrial, Irene M.

“…Introduction Many transcription factors (TF) are promising therapeutic targets in hematological malignancies but have been mislabeled as ‘undruggable’ due to…”
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In Situ Characterization of Chromatin Landscape in Progression of Smoldering Precursor Stage to Multiple Myeloma by Rahmat, Mahshid, Vinyard, Michael, Sklavenitis-Pistofidis, Romanos, Clement, Kendell, Lightbody, Elizabeth D., Boehner, Cody J., Hevenor, Laura, Perry, Jacqueline, Getz, Gad, Ghobrial, Irene

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Genome Sequencing to Discover Drivers of Clonal Expansion in Smoldering Multiple Myeloma by Alberge, Jean-Baptiste, Dutta, Ankit K., Lightbody, Elizabeth D., Poletti, Andrea, Wallin, Sofia, Dunford, Andrew, Coorens, Tim, Loinaz, Xavi, Boehner, Cody J., Su, Nang Kham, Hevenor, Laura, Towle, Katherine, Perry, Jacqueline, Kübler, Kirsten, Sklavenitis-Pistofidis, Romanos, Hess, Julian, Stewart, Chip, Getz, Gad, Ghobrial, Irene M.

“…Background Better prediction models are required to identify patients with high-risk smoldering multiple myeloma (SMM) who can benefit from early intervention…”
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Single-Cell RNA Sequencing Reveals Hypo-Responsiveness of T and NK Cells to Interferon Stimulation As an Immune Hallmark in Asymptomatic Waldenstrom's Macroglobulinemia by Konishi, Yoshinobu, Sklavenitis-Pistofidis, Romanos, Mallory, Daniel L., Wu, Ting, Aranha, Michelle P., Tsuji, Junko, Haradhvala, Nicholas J, Lightbody, Elizabeth D., Towle, Katherine, Hevenor, Laura, Tsakmaklis, Nickolas, Wang, Xiyue, Canning, Alexa G, Liacos, Christine-Ivy, Kastritis, Efstathios, Dimopoulos, Meletios Athanasios, Treon, Steven P, Getz, Gady, Ghobrial, Irene M.

“…Introduction Waldenstrom macroglobulinemia (WM) is a rare, indolent non-Hodgkin lymphoplasmacytic lymphoma of the bone marrow (BM), characterized by monoclonal…”
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High-Throughput Plasma Proteomics to Define the Precursor Multiple Myeloma Proteome and Identify Candidate High-Risk Disease Biomarkers of Progression by Lightbody, Elizabeth D., Mani, D. R., Keshishian, Hasmik, El-Khoury, Habib, Dutta, Ankit K., Barr, Hadley, Udeshi, Namrata, Bertamini, Luca, Kham Su, Nang, Boehner, Cody J., Hevenor, Laura, Towle, Katherine, Fleming, Grace, Cea-Curry, Christian, Perry, Jacqueline, Horowitz, Erica M., Davis, Maya, Cowan, Annie, Marinac, Catherine R., Gillette, Michael, Carr, Steven A., Ghobrial, Irene M.

“…Introduction Multiple Myeloma (MM) develops from well-defined precursors Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Multiple…”
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Single-Cell RNA Sequencing of Circulating Tumor Cells in Precursor Myeloma Patients Reveals Mechanisms of Disease Dissemination by Lightbody, Elizabeth D., Sklavenitis-Pistofidis, Romanos, Firer, Danielle T., Tsuji, Junko, Agius, Mike P., Dutta, Ankit K., Wu, Ting, Barr, Hadley, Kim, Sungjae, Coorens, Tim, Alberge, Jean-Baptiste, Aranha, Michelle P., Haradhvala, Nicholas J, Kham Su, Nang, Boehner, Cody J., Walsh, Kelly, Rahmat, Mahshid, Konishi, Yoshinobu, Hevenor, Laura, Towle, Katherine, Horowitz, Erica M., Perry, Jacqueline, Fleming, Grace, El-Khoury, Habib, Vinyard, Michael, Cowan, Annie, Auclair, Daniel, Ready, John E., Marinac, Catherine R., Getz, Gad, Ghobrial, Irene M.

“…Introduction Multiple Myeloma (MM) is preceded by the precursors Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Multiple Myeloma…”
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Monitoring Plasma Cells and Clonal Emergence through Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma by Dutta, Ankit K., Alberge, Jean-Baptiste, Lightbody, Elizabeth D., Boehner, Cody J., Sklavenitis-Pistofidis, Romanos, Cao, Amanda, Mouhieddine, Tarek H., Cowan, Anna, Su, Nang Kham, Dunford, Andrew, Horowitz, Erica, Barr, Hadley, Beckwith, Jenna B., Hevenor, Laura, Perry, Jacqueline, Zepp, Ornkleaw, Bui, Thai, Gross, Steven, Nadeem, Omar, Stewart, Chip, Auclair, Daniel, Getz, Gad, Ghobrial, Irene

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Single-Cell RNA-Sequencing of 245 Tumor Samples from Patients with MGUS and Smoldering Multiple Myeloma Reveals Novel Insights into Malignant Plasma Cell Biology by Tsuji, Junko, Lightbody, Elizabeth D., Sklavenitis-Pistofidis, Romanos, Agius, Michael P., Rahmat, Mahshid, Barr, Hadley, Konishi, Yoshinobu, Dutta, Ankit K., Su, Nang Kham, Boehner, Cody J., Firer, Danielle T., Wu, Ting, Aranha, Michelle P., Hevenor, Laura, Horowitz, Erica, Perry, Jacqueline, Aguet, François, Haradhvala, Nicholas J., Boiarsky, Rebecca, Getz, Gad, Ghobrial, Irene

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High-Throughput Plasma Proteomic Profiling to Identify Candidate High-Risk Disease Biomarkers in Precursor Multiple Myeloma Patients by Lightbody, Elizabeth D., Keshishian, Hasmik, El-Khoury, Habib, Dutta, Ankit K., Barr, Hadley, Barbagallo, Jes, Udeshi, Namrata, Agius, Michael P., Kham Su, Nang, Boehner, Cody J., Hevenor, Laura, Towle, Katherine, Cea-Curry, Christian J., Perry, Jacqueline, Horowitz, Erica, Davis, Maya I., Cowan, Anna, Mills, Evan, Rucevic, Marijana, Mani, DR, Auclair, Daniel, Marinac, Catherine R., Gillette, Michael A, Carr, Steven A, Ghobrial, Irene

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Reconstructing the Genomic History of Multiple Myeloma Precursor Disease: Novel Insights and Clinical Applicability by Alberge, Jean-Baptiste, Dutta, Ankit K., Lightbody, Elizabeth D., Poletti, Andrea, Dunford, Andrew, Priebe, Oliver, Hess, Julian M., Boehner, Cody J., Sklavenitis-Pistofidis, Romanos, Su, Nang Kham, Horowitz, Erica, Barr, Hadley, Beckwith, Jenna B., Hevenor, Laura, Towle, Katherine, Perry, Jacqueline, Rheinbay, Esther, Stewart, Chip, Getz, Gad, Ghobrial, Irene

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Single-Cell RNA Sequencing of Rare Circulating Tumor Cells in Precursor Myeloma Patients Reveals Molecular Underpinnings of Tumor Cell Circulation by Lightbody, Elizabeth D., Firer, Danielle T., Sklavenitis-Pistofidis, Romanos, Tsuji, Junko, Agius, Michael P., Dutta, Ankit K., Wu, Ting, Barr, Hadley, Rahmat, Mahshid, Konishi, Yoshinobu, Aranha, Michelle P., Vinyard, Michael, Alberge, Jean-Baptiste, Kham Su, Nang, Boehner, Cody J., Hevenor, Laura, El-Khoury, Habib, Towle, Katherine, Cea-Curry, Christian J., Horowitz, Erica, Perry, Jacqueline, Cowan, Anna, Justis, Anna V., Auclair, Daniel, Marinac, Catherine R., Getz, Gad, Ghobrial, Irene

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MinimuMM-seq: Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma Pathology by Dutta, Ankit K, Alberge, Jean-Baptiste, Lightbody, Elizabeth D, Boehner, Cody J, Dunford, Andrew, Sklavenitis-Pistofidis, Romanos, Mouhieddine, Tarek H, Cowan, Annie N, Su, Nang Kham, Horowitz, Erica M, Barr, Hadley, Hevenor, Laura, Beckwith, Jenna B, Perry, Jacqueline, Cao, Amanda, Lin, Ziao, Kuhr, Frank K, Mastro, Richard G Del, Nadeem, Omar, Greipp, Patricia T, Stewart, Chip, Auclair, Daniel, Getz, Gad, Ghobrial, Irene M

“…Multiple myeloma (MM) develops from well-defined precursor stages; however, invasive bone marrow (BM) biopsy limits screening and monitoring strategies for…”
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OA-40 SWIFT-Seq: Single-Cell RNA Sequencing of Circulating Tumor Cells as a Comprehensive Clinically Applicable Liquid Biopsy Test for Patients With Multiple Myeloma and Its Precursor Conditions by Lightbody, Elizabeth, Sklavenitis-Pistofidis, Romanos, Wu, Ting, Tsuji, Junko, Firer, Danielle, Agius, Michael, Dutta, Ankit, Barr, Hadley, Kim, Sungjae, Alberge, Jean-Baptiste, Nersesian, Sarah, Coorens, Tim, Haradhvala, Nicholas, Su, Nang Kham, Boehner, Cody J., Aranha, Michelle, Rahmat, Mahshid, Konishi, Yoshinobu, Hevenor, Laura, Towle, Katherine, Horowitz, Erica, Perry, Jacqueline, Marinac, Catherine R., Getz, Gad, Ghobrial, Irene

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OA-35 High-throughput plasma proteomics to define the precursor multiple myeloma proteome and identify candidate high-risk disease biomarkers of progression by Lightbody, Elizabeth, Mani, DR, Keshishian, Hasmik, El-Khoury, Habib, Dutta, Ankit, Barr, Hadley, Udeshi, Namrata, Agius, Michael, Bertamini, Luca, Su, Nang Kham, Boehner, Cody, Hevenor, Laura, Towle, Katherine, Cea-Curry, Christian, Fleming, Grace, Perry, Jacqueline, Horowitz, Erica, Davis, Maya, Cowan, Anna, Auclair, Daniel, Marinac, Catherine, Gillette, Michael, Carr, Steven, Ghobrial, Irene

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P-097 Single-cell RNA sequencing of circulating tumor cells in precursor myeloma patients reveals early mechanisms of disease dissemination by Lightbody, Elizabeth, Firer, Danielle, Sklavenitis-Pistofidis, Romanos, Tsuji, Junko, Agius, Michael, Dutta, Ankit, Wu, Ting, Barr, Hadley, Rahmat, Mahshid, Konishi, Yoshinobu, Aranha, Michelle, Alberge, Jean-Baptiste, Su, Nang Kham, Boehner, Cody, Hevenor, Laura, El-Khoury, Habib, Towle, Katherine, Cea-Curry, Christian, Horowitz, Erica, Perry, Jacqueline, Cowan, Anna, Auclair, Daniel, Marinac, Catherine, Getz, Gad, Ghobrial, Irene

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P-055: Monitoring the emergence of multiple myeloma high-risk subclones with whole-genome sequencing of circulating tumor cells by Alberge, Jean-Baptiste, Dutta, Ankit, Lightbody, Elizabeth, Dunford, Andrew, Stewart, Chip, Boehner, Cody, Sklavenitis-Pistofidis, Romanos, Cao, Amanda, Mouhieddine, Tarek, Cowan, Annie, Su, Nang, Horowitz, Erica, Barr, Hadley, Hevenor, Laura, Lin, Ziao, Perry, Jacqueline, Nadeem, Omar, Auclair, Daniel, Getz, Gad, Ghobrial, Irene

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Abstract 640: Genome sequencing of circulating multiple myeloma cells for minimally invasive molecular characterization of precursor disease pathology by Dutta, Ankit K., Alberge, Jean-Baptiste, Lightbody, Elizabeth D., Sklavenitis-Pistofidis, Romanos, Boehner, Cody J., Mouhieddine, Tarek H., Cowan, Anna, Su, Nang Kham, Horowitz, Erica M., Dunford, Andrew, Stewart, Chip, Lin, Ziao, Hevenor, Laura, Barr, Hadley, Cao, Amanda, Zepp, Ornkleaw, Bui, Thai, Gross, Steve, Auclair, Daniel, Getz, Gad, Ghobrial, Irene M.

“…Abstract Introduction: Multiple myeloma (MM) develops from indolent stages monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple…”
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Abstract 641: Single-cell RNA sequencing of rare circulating tumor cells in precursor myeloma patients reveals molecular underpinnings of tumor cell circulation by Lightbody, Elizabeth D., Firer, Danielle T., Sklavenitis-Pistofidis, Romanos, Agius, Michael, Dutta, Ankit K., Aranha, Michelle, Alberge, Jean-Baptiste, Hevenor, Laura, Su, Nang Kham, Boehner, Cody, Horowitz, Erica, Perry, Jacqueline, Cowan, Anna, Barr, Hadley, Justis, Anna, Auclair, Daniel, Marinac, Catherine R., Getz, Gad, Ghobrial, Irene

“…Abstract Background: Multiple Myeloma (MM) is a hematological malignancy characterized by abnormal proliferation of terminally differentiated plasma cells…”
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