Search Results - "Heuston, Sinéad"

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    Isoprenoid biosynthesis in bacterial pathogens by HEUSTON, Sinéad, BEGLEY, Máire, GAHAN, Cormac G. M, HILL, Colin

    “…Isoprenoid biosynthesis is essential for cell survival. Over 35 000 isoprenoid molecules have been identified to date in the three domains of life (bacteria,…”
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    Journal Article
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    Analysis of the Isoprenoid Biosynthesis Pathways in Listeria monocytogenes Reveals a Role for the Alternative 2-C-Methyl-D-Erythritol 4-Phosphate Pathway in Murine Infection by Begley, Máire, Bron, Peter A, Heuston, Sinead, Casey, Pat G, Englert, Nadine, Wiesner, Jochen, Jomaa, Hassan, Gahan, Cormac G.M, Hill, Colin

    Published in Infection and Immunity (01-11-2008)
    “…Most bacteria synthesize isoprenoids through one of two essential pathways which provide the basic building block, isopentyl diphosphate (IPP): either the…”
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    HmgR, a key enzyme in the mevalonate pathway for isoprenoid biosynthesis, is essential for growth of Listeria monocytogenes EGDe by HEUSTON, Sinead, BEGLEY, Maire, DAVEY, Martin S, EBERL, Matthias, CASEY, Pat G, HILL, Colin, GAHAN, Cormac G. M

    “…Isoprenoids may be synthesized via one of two pathways, the classical mevalonate pathway or the alternative 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway…”
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    Journal Article
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