Search Results - "Heus, Henk"

Hemimelic extra toes and Hammer toe are distinct mutations that show a genetic interaction by Heus, H C, Luijsterburg, A J, van Baren, M J, Breedveld, G J, Joosse, M N, Nieuwenhuizen, I M, Vermeij-Keers, C, Oostra, B A, Heutink, P

“…The mutations underlying the mouse Hemimelic extra toes (Hx) phenotype, characterized by preaxial polydactyly and shortening of the tibia, and the Hammer toe…”
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Inactivation of the EGF‐TM7 receptor EMR4 after the Pan‐Homo divergence by Hamann, Jörg, Kwakkenbos, Mark J., de Jong, Esther C., Heus, Henk, Olsen, Anne S., van Lier, René A.W.

“…We here report on the identification of a novel human EGF‐TM7 receptor, designated EMR4. Like most EGF‐TM7 receptor genes, EMR4 is localized on the short arm…”
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Clinical and genetic studies on 12 preaxial polydactyly families and refinement of the localisation of the gene responsible to a 1.9 cM region on chromosome 7q36 by Zguricas, Julia, Heus, Henk, Morales-Peralta, Estela, Breedveld, Guido, Kuyt, Bertus, Mumcu, Ethem F, Bakker, Wendela, Akarsu, Nurten, Kay, Simon P J, Hovius, Steven E R, Heredero-Baute, Luis, Oostra, Ben A, Heutink, Peter

“…Polydactyly is the most frequently observed congenital hand malformation with a prevalence between 5 and 19 per 10 000 live births. It can occur as an isolated…”
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A Physical and Transcriptional Map of the Preaxial Polydactyly Locus on Chromosome 7q36 by Heus, Henk C., Hing, Anne, van Baren, Marijke J., Joosse, Marijke, Breedveld, Guido J., Wang, Jen C., Burgess, Andrea, Donnis-Keller, Helen, Berglund, Cathleen, Zguricas, Julia, Scherer, Stephen W., Rommens, Johanna M., Oostra, Ben A., Heutink, Peter

“…Preaxial polydactyly is a congenital hand malformation that includes duplicated thumbs, various forms of triphalangeal thumbs, and duplications of the index…”
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Genetics of limb development and congenital hand malformations by ZGURICAS, J, BAKKER, W. F, HEUS, H, LINDHOUT, D, HEUTINK, P, HOVIUS, S. E. R

“…The vertebrate limb bud develops along three different axes: proximodistal, anteroposterior, and dorsoventral. Several genetic factors responsible for control…”
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