Search Results - "Heus, Ferry"

Fasciola hepatica Surface Coat Glycoproteins Contain Mannosylated and Phosphorylated N-glycans and Exhibit Immune Modulatory Properties Independent of the Mannose Receptor by Ravidà, Alessandra, Aldridge, Allison M, Driessen, Nicole N, Heus, Ferry A H, Hokke, Cornelis H, O'Neill, Sandra M

“…Fascioliasis, caused by the liver fluke Fasciola hepatica, is a neglected tropical disease infecting over 1 million individuals annually with 17 million people…”
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Miniaturized bioaffinity assessment coupled to mass spectrometry for guided purification of bioactives from toad and cone snail by Heus, Ferry, Otvos, Reka A, Aspers, Ruud L E G, van Elk, Rene, Halff, Jenny I, Ehlers, Andreas W, Dutertre, Sébastien, Lewis, Richard J, Wijmenga, Sybren, Smit, August B, Niessen, Wilfried M A, Kool, Jeroen

“…A nano-flow high-resolution screening platform, featuring a parallel chip-based microfluidic bioassay and mass spectrometry coupled to nano-liquid…”
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Microfractionation Revisited: A 1536 Well High Resolution Screening Assay by Giera, Martin, Heus, Ferry, Janssen, Laura, Kool, Jeroen, Lingeman, Henk, Irth, Hubertus

“…The aim of the here presented study was to combine high performance liquid chromatography with plate reader technology in order to overcome certain drawbacks…”
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Analysis of glutathione adducts of patulin by means of liquid chromatography (HPLC) with biochemical detection (BCD) and electrospray ionization tandem mass spectrometry (ESI-MS/MS) by Schebb, Nils Helge, Faber, Helene, Maul, Ronald, Heus, Ferry, Kool, Jeroen, Irth, Hubertus, Karst, Uwe

“…A novel method for the identification of glutathione/electrophile adducts that are inhibiting glutathione-S-transferase (GST) activity was developed and…”
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High-Resolution Fractionation after Gas Chromatography for Effect-Directed Analysis by Pieke, Eelco, Heus, Ferry, Kamstra, Jorke H, Mladic, Marija, Velzen, Martin van, Kamminga, Dik, Lamoree, Marja H, Hamers, Timo, Leonards, Pim, Niessen, Wilfried M. A, Kool, Jeroen

“…This research presents an analytical technology for highly efficient, high-resolution, and high-yield fractionation of compounds after gas chromatography (GC)…”
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An efficient analytical platform for on-line microfluidic profiling of neuroactive snake venoms towards nicotinic receptor affinity by Heus, Ferry, Vonk, Freek, Otvos, Reka A., Bruyneel, Ben, Smit, August B., Lingeman, Henk, Richardson, Michael, Niessen, Wilfried M.A., Kool, Jeroen

“…Venomous snakes have evolved their efficient venomous arsenals mainly to immobilize prey. The highly variable toxic peptides in these venoms target a myriad of…”
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Development of a Countergradient Parking System for Gradient Liquid Chromatography with Online Biochemical Detection of Serine Protease Inhibitors by Schebb, Nils Helge, Heus, Ferry, Saenger, Thorsten, Karst, Uwe, Irth, Hubertus, Kool, Jeroen

“…A gradient HPLC approach in combination with a countergradient system for online biochemical detection (BCD) to screen for inhibitors of serine proteases is…”
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Online magnetic bead based dynamic protein affinity selection coupled to LC–MS for the screening of acetylcholine binding protein ligands by Pochet, Lionel, Heus, Ferry, Jonker, Niels, Lingeman, Henk, Smit, August B., Niessen, Wilfried M.A., Kool, Jeroen

“…A magnetic beads based affinity-selection methodology towards the screening of acetylcholine binding protein (AChBP) binders in mixtures and pure compound…”
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Analytical workflow for rapid screening and purification of bioactives from venom proteomes by Otvos, Reka A., Heus, Ferry, Vonk, Freek J., Halff, Jenny, Bruyneel, Ben, Paliukhovich, Iryna, Smit, August B., Niessen, Wilfried M.A., Kool, Jeroen

“…Animal venoms are important sources for finding new pharmaceutical lead molecules. We used an analytical platform for initial rapid screening and…”
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Development of a microfluidic confocal fluorescence detection system for the hyphenation of nano-LC to on-line biochemical assays by Heus, Ferry, Giera, Martin, de Kloe, Gerdien E, van Iperen, Dick, Buijs, Joost, Nahar, Tariq T, Smit, August B, Lingeman, Henk, de Esch, Iwan J. P, Niessen, Wilfried M. A, Irth, Hubertus, Kool, Jeroen

“…One way to profile complex mixtures for receptor affinity is to couple liquid chromatography (LC) on-line to biochemical detection (BCD). A drawback of this…”
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Application of cytochrome P450 BM3 mutants as biocatalysts for the profiling of estrogen receptor binding metabolites of the mycotoxin zearalenone by Reinen, Jelle, Kalma, Livia L., Begheijn, Selina, Heus, Ferry, Commandeur, Jan N.M., Vermeulen, Nico P.E.

“…The estrogenic mycotoxin zearalenone (ZEN) can undergo hepatic reductive metabolism to form the estrogenic α and β isomers of zearalenol. ZEN also undergoes…”
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Analysis of glutathione adducts of patulin by means of liquid chromatography (HPLC) with biochemical detection (BCD) and electrospray ionization tandem mass spectrometry (ESI-MS/MS) : Advances in analytical separations by SCHEBB, Nils Helge, FABER, Helene, MAUL, Ronald, HEUS, Ferry, KOOL, Jeroen, IRTH, Hubertus, KARST, Uwe

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Development of On-line Liquid Chromatography-Biochemical Detection for Soluble Epoxide Hydrolase Inhibitors in Mixtures by Falck, David, Schebb, Nils Helge, Prihatiningtyas, Setyo, Zhang, Jiawen, Heus, Ferry, Morisseau, Christophe, Kool, Jeroen, Hammock, Bruce D., Niessen, Wilfried M. A.

“…In this study, an end-point-based fluorescence assay for soluble epoxide hydrolase (sEH) was transformed into an on-line continuous-flow format. The on-line…”
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High-resolution bioactivity profiling of mixtures toward the acetylcholine binding protein using a nanofractionation spotter technology by Kool, Jeroen, Heus, Ferry, de Kloe, Gerdien, Lingeman, Henk, Smit, August B, Leurs, Rob, Edink, Ewald, De Esch, Iwan J P, Irth, Hubertus, Niessen, Wilfried M A

“…This study describes the evaluation, validation, and use of contactless postcolumn fractionation of bioactive mixtures with acetylcholine binding protein…”
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