The global threat of antimicrobial resistance: science for intervention

Abstract In the last decade we have witnessed a dramatic increase in the proportion and absolute number of bacterial pathogens resistant to multiple antibacterial agents. Multidrug-resistant bacteria are currently considered as an emergent global disease and a major public health problem. The B-Deba...

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Bibliographic Details
Published in:	New microbes and new infections Vol. 6; no. C; pp. 22 - 29
Main Authors:	Roca, I, Akova, M, Baquero, F, Carlet, J, Cavaleri, M, Coenen, S, Cohen, J, Findlay, D, Gyssens, I, Heure, O.E, Kahlmeter, G, Kruse, H, Laxminarayan, R, Liébana, E, López-Cerero, L, MacGowan, A, Martins, M, Rodríguez-Baño, J, Rolain, J.-M, Segovia, C, Sigauque, B, Tacconelli, E, Wellington, E, Vila, J
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-07-2015 European Society of Clinical Microbiology and Infectious Diseases Elsevier
Subjects:	Administració de medicaments Administration of drugs Antibiotic consumption antibiotic resistance antibiotic stewardship Antibiotics antibiotics as growth promoters Antibiòtics Bacteris patògens drug discovery Drug resistance Drug utilization infection control measures Infectious Disease Mini-Review multidrug resistant bacteria Pathogenic bacteria Public health Resistència als medicaments Salut pública self-medication surveillance Utilització de medicaments wastewater treatment plants infection control measures multidrug resistant bacteria wastewater treatment plants drug discovery antibiotic resistance antibiotics as growth promoters self-medication antibiotic stewardship surveillance Antibiotic consumption
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Summary:	Abstract In the last decade we have witnessed a dramatic increase in the proportion and absolute number of bacterial pathogens resistant to multiple antibacterial agents. Multidrug-resistant bacteria are currently considered as an emergent global disease and a major public health problem. The B-Debate meeting brought together renowned experts representing the main stakeholders (i.e. policy makers, public health authorities, regulatory agencies, pharmaceutical companies and the scientific community at large) to review the global threat of antibiotic resistance and come up with a coordinated set of strategies to fight antimicrobial resistance in a multifaceted approach. We summarize the views of the B-Debate participants regarding the current situation of antimicrobial resistance in animals and the food chain, within the community and the healthcare setting as well as the role of the environment and the development of novel diagnostic and therapeutic strategies, providing expert recommendations to tackle the global threat of antimicrobial resistance.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	2052-2975 2052-2975
DOI:	10.1016/j.nmni.2015.02.007