Search Results - "Heunks, Leo"

Critical illness-associated diaphragm weakness by Dres, Martin, Goligher, Ewan C., Heunks, Leo M. A., Brochard, Laurent J.

“…Diaphragm weakness is highly prevalent in critically ill patients. It may exist prior to ICU admission and may precipitate the need for mechanical ventilation…”
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Physiology of the Respiratory Drive in ICU Patients: Implications for Diagnosis and Treatment by Jonkman, Annemijn H, de Vries, Heder J, Heunks, Leo M A

“…This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online…”
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Diaphragm Pathology in Critically Ill Patients With COVID-19 and Postmortem Findings From 3 Medical Centers by Shi, Zhonghua, de Vries, Heder J, Vlaar, Alexander P J, van der Hoeven, Johannes, Boon, Reinier A, Heunks, Leo M A, Ottenheijm, Coen A C

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Divergent SARS‐CoV‐2‐specific T‐ and B‐cell responses in severe but not mild COVID‐19 patients by Oja, Anna E., Saris, Anno, Ghandour, Cherien A., Kragten, Natasja A.M., Hogema, Boris M., Nossent, Esther J., Heunks, Leo M.A., Cuvalay, Susan, Slot, Ed, Linty, Federica, Swaneveld, Francis H., Vrielink, Hans, Vidarsson, Gestur, Rispens, Theo, Schoot, Ellen, Lier, René A.W., Ten Brinke, Anja, Hombrink, Pleun

“…Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the causative agent of the current coronavirus disease 2019 (COVID‐19) pandemic. Understanding…”
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Diaphragm-Protective Mechanical Ventilation to Improve Outcomes in ICU Patients? by Heunks, Leo, Ottenheijm, Coen

“…[...]diaphragm dysfunction is highly prevalent. [...]this study demonstrates a relationship between changes in diaphragm thickness and diaphragm effort…”
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Oxygen-induced hypercapnia in COPD: myths and facts by Abdo, Wilson F, Heunks, Leo M A

“…During our medical training, we learned that oxygen administration in patients with chronic obstructive pulmonary disease (COPD) induces hypercapnia through…”
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Clinical strategies for implementing lung and diaphragm-protective ventilation: avoiding insufficient and excessive effort by Goligher, Ewan C., Jonkman, Annemijn H., Dianti, Jose, Vaporidi, Katerina, Beitler, Jeremy R., Patel, Bhakti K., Yoshida, Takeshi, Jaber, Samir, Dres, Martin, Mauri, Tommaso, Bellani, Giacomo, Demoule, Alexandre, Brochard, Laurent, Heunks, Leo

“…Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury to the lung is mediated by excessive mechanical stress and strain,…”
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Levosimendan efficacy and safety : 20 Years of SIMDAX in clinical use by Papp, Zoltán, Agostoni, Piergiuseppe, Alvarez, Julian, Bettex, Dominique, Bouchez, Stefan, Brito, Dulce, Cˇerný, Vladimir, Comin-Colet, Josep, Crespo-Leiro, Marisa G, Delgado, Juan F, Édes, Istvan, Eremenko, Alexander A, Farmakis, Dimitrios, Fedele, Francesco, Fonseca, Cândida, Fruhwald, Sonja, Girardis, Massimo, Guarracino, Fabio, Harjola, Veli-Pekka, Heringlake, Matthias, Herpain, Antoine, Heunks, Leo MA, Husebye, Tryggve, Ivancan, Višnja, Karason, Kristjan, Kaul, Sundeep, Kivikko, Matti, Kubica, Janek, Masip, Josep, Matskeplishvili, Simon, Mebazaa, Alexandre, Nieminen, Markku S, Oliva, Fabrizio, Papp, Julius-Gyula, Parissis, John, Parkhomenko, Alexander, Põder, Pentti, Pölzl, Gerhard, Reinecke, Alexander, Ricksten, Sven-Erik, Riha, Hynek, Rudiger, Alain, Sarapohja, Toni, Schwinger, Robert HG, Toller, Wolfgang, Tritapepe, Luigi, Tschöpe, Carsten, Wikström, Gerhard, von Lewinski, Dirk, Vrtovec, Bojan, Pollesello, Piero

“…Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. Levosimendan was first approved for clinical use in 2000, when authorization was…”
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The impact of critical illness on the expiratory muscles and the diaphragm assessed by ultrasound in mechanical ventilated children by IJland, Marloes M., Lemson, Joris, van der Hoeven, Johannes G., Heunks, Leo M. A.

“…Background Critical illness has detrimental effects on the diaphragm, but the impact of critical illness on other major muscles of the respiratory pump has…”
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Determining the optimal number of lung ultrasound zones to monitor COVID-19 patients: can we keep it ultra-short and ultra-simple? by Heldeweg, Micah L. A., Lieveld, Arthur W. E., de Grooth, Harm J., Heunks, Leo M. A., Tuinman, Pieter R.

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Functional assessment of the diaphragm by speckle tracking ultrasound during inspiratory loading by Oppersma, Eline, Hatam, Nima, Doorduin, Jonne, van der Hoeven, Johannes G, Marx, Gernot, Goetzenich, Andreas, Fritsch, Sebastian, Heunks, Leo M A, Bruells, Christian S

“…Assessment of diaphragmatic effort is challenging, especially in critically ill patients in the phase of weaning. Fractional thickening during inspiration…”
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Monitoring of the respiratory muscles in the critically ill by Doorduin, Jonne, van Hees, Hieronymus W H, van der Hoeven, Johannes G, Heunks, Leo M A

“…Evidence has accumulated that respiratory muscle dysfunction develops in critically ill patients and contributes to prolonged weaning from mechanical…”
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Highlights in acute respiratory failure by Scala, Raffaele, Heunks, Leo

“…Acute respiratory failure (ARF) is a devastating condition for patients that results from either impaired function of the respiratory muscle pump or from…”
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Estimation of the diaphragm neuromuscular efficiency index in mechanically ventilated critically ill patients by Jansen, Diana, Jonkman, Annemijn H, Roesthuis, Lisanne, Gadgil, Suvarna, van der Hoeven, Johannes G, Scheffer, Gert-Jan J, Girbes, Armand, Doorduin, Jonne, Sinderby, Christer S, Heunks, Leo M A

“…Diaphragm dysfunction develops frequently in ventilated intensive care unit (ICU) patients. Both disuse atrophy (ventilator over-assist) and high respiratory…”
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Respiratory muscle ultrasonography: methodology, basic and advanced principles and clinical applications in ICU and ED patients—a narrative review by Tuinman, Pieter R., Jonkman, Annemijn H., Dres, Martin, Shi, Zhong-Hua, Goligher, Ewan C., Goffi, Alberto, de Korte, Chris, Demoule, Alexandre, Heunks, Leo

“…Respiratory muscle ultrasound is used to evaluate the anatomy and function of the respiratory muscle pump. It is a safe, repeatable, accurate, and non-invasive…”
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Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study by Laffey, John G., Bellani, Giacomo, Pham, Tài, Fan, Eddy, Madotto, Fabiana, Bajwa, Ednan K., Brochard, Laurent, Clarkson, Kevin, Esteban, Andres, Gattinoni, Luciano, van Haren, Frank, Heunks, Leo M., Kurahashi, Kiyoyasu, Laake, Jon Henrik, Larsson, Anders, McAuley, Daniel F., McNamee, Lia, Nin, Nicolas, Qiu, Haibo, Ranieri, Marco, Rubenfeld, Gordon D., Thompson, B. Taylor, Wrigge, Hermann, Slutsky, Arthur S., Pesenti, Antonio

“…Purpose To improve the outcome of the acute respiratory distress syndrome (ARDS), one needs to identify potentially modifiable factors associated with…”
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Expiratory Muscle Relaxation-Induced Ventilator Triggering: A Novel Patient-Ventilator Dyssynchrony by Jonkman, Annemijn H, Holleboom, Minke C, de Vries, Heder J, Vriends, Marijn, Tuinman, Pieter R, Heunks, Leo M A

“…In critically ill patients receiving mechanical ventilation, expiratory muscles are recruited with high respiratory loading and/or low inspiratory muscle…”
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Abdominal functional electrical stimulation to assist ventilator weaning in critical illness: a double-blinded, randomised, sham-controlled pilot study by McCaughey, Euan J, Jonkman, Annemijn H, Boswell-Ruys, Claire L, McBain, Rachel A, Bye, Elizabeth A, Hudson, Anna L, Collins, David W, Heunks, Leo M A, McLachlan, Angus J, Gandevia, Simon C, Butler, Jane E

“…For every day a person is dependent on mechanical ventilation, respiratory and cardiac complications increase, quality of life decreases and costs increase by…”
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ERS clinical practice guidelines: high-flow nasal cannula in acute respiratory failure by Oczkowski, Simon, Ergan, Begüm, Bos, Lieuwe, Chatwin, Michelle, Ferrer, Miguel, Gregoretti, Cesare, Heunks, Leo, Frat, Jean-Pierre, Longhini, Federico, Nava, Stefano, Navalesi, Paolo, Ozsancak Uğurlu, Aylin, Pisani, Lara, Renda, Teresa, Thille, Arnaud W, Winck, João Carlos, Windisch, Wolfram, Tonia, Thomy, Boyd, Jeanette, Sotgiu, Giovanni, Scala, Raffaele

“…High-flow nasal cannula (HFNC) has become a frequently used noninvasive form of respiratory support in acute settings; however, evidence supporting its use has…”
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The Calcium Sensitizer Levosimendan Improves Human Diaphragm Function by DOORDUIN, Jonne, SINDERBY, Christer A, BECK, Jennifer, STEGEMAN, Dick F, HEES, Hieronymus W. H. Van, DER HOEVEN, Johannes G. Van, HEUNKS, Leo M. A

“…Acquired diaphragm muscle weakness is a key feature in several chronic conditions, including chronic obstructive pulmonary disease, congestive heart failure,…”
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