Search Results - "Hetzler, Zach"

Ratiometric nonfluorescent CRISPR assay utilizing Cas12a-induced plasmid supercoil relaxation by Mohammad, Noor, Talton, Logan, Dalgan, Selen, Hetzler, Zach, Steksova, Anastasiia, Wei, Qingshan

“…Most CRISPR-based biosensors rely on labeled reporter molecules and expensive equipment for signal readout. A recent approach quantifies analyte concentration…”
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Flexible sensor patch for continuous carbon dioxide monitoring by Hetzler, Zach, Wang, Yan, Krafft, Danny, Jamalzadegan, Sina, Overton, Laurie, Kudenov, Michael W., Ligler, Frances S., Wei, Qingshan

“…Monitoring and measurement of carbon dioxide (CO 2 ) is critical for many fields. The gold standard CO 2 sensor, the Severinghaus electrode, has remained…”
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Unidirectional trans-cleaving behavior of CRISPR-Cas12a unlocks for an ultrasensitive assay using hybrid DNA reporters containing a 3′ toehold by Mohammad, Noor, Talton, Logan, Hetzler, Zach, Gongireddy, Megha, Wei, Qingshan

“…Abstract CRISPR-Cas12a can induce nonspecific trans-cleavage of dsDNA substrate, including long and stable λ DNA. However, the mechanism behind this is still…”
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Liquid Metal‐Based Biosensors: Fundamentals and Applications by Jamalzadegan, Sina, Kim, Sooyoung, Mohammad, Noor, Koduri, Harshita, Hetzler, Zach, Lee, Giwon, Dickey, Michael D., Wei, Qingshan

“…Biosensors are analytical tools for monitoring various parameters related to living organisms, such as humans and plants. Liquid metals (LMs) have emerged as a…”
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Adeno-associated virus genome quantification with amplification-free CRISPR-Cas12a by Hetzler, Zach, Marinakos, Stella M., Lott, Noah, Mohammad, Noor, Lass-Napiorkowska, Agnieszka, Kolbe, Jenna, Turrentine, Lauren, Fields, Delaney, Overton, Laurie, Marie, Helena, Hucknall, Angus, Rammo, Oliver, George, Henry, Wei, Qingshan

“…Efficient manufacturing of recombinant Adeno-Associated Viral (rAAV) vectors to meet rising clinical demand remains a major hurdle. One of the most significant…”
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Single-use biosensors for biomanufacturing: Perspective on the state-of-the-art by Hetzler, Zach, Lott, Noah, Dey Poonam, Aditi, Dalgan, Selen, Wei, Qingshan

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Low-rate smartphone videoscopy for microsecond luminescence lifetime imaging with machine learning by Wang, Yan, Sadeghi, Sina, Velayati, Alireza, Paul, Rajesh, Hetzler, Zach, Danilov, Evgeny, Ligler, Frances S, Wei, Qingshan

“…Time-resolved techniques have been widely used in time-gated and luminescence lifetime imaging. However, traditional time-resolved systems require expensive…”
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Low-Rate Smartphone Videoscopy for Microsecond Luminescence Lifetime Imaging with Machine Learning by Wang, Yan, Sadeghi, Sina, Paul, Rajesh, Hetzler, Zach, Danilov, Evgeny, Ligler, Frances S, Wei, Qingshan

“…PNAS Nexus, 2023, pgad313 Time-resolved techniques have been widely used in time-gated and luminescence lifetime imaging. However, traditional time-resolved…”
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