Search Results - "Hetzel, M R"

Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer by Vincent, E E, Elder, D J E, Thomas, E C, Phillips, L, Morgan, C, Pawade, J, Sohail, M, May, M T, Hetzel, M R, Tavaré, J M

“…Background: The activity of the protein kinase Akt is frequently dysregulated in cancer and is an important factor in the growth and survival of tumour cells…”
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Primary tracheal tumours: a national survey by Gelder, C M, Hetzel, M R

“…BACKGROUND--Primary tracheal tumours are rare, so few physicians have extensive experience of their management. No direct comparisons have been made of…”
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Endoscopic palliation of tracheobronchial malignancies by Hetzel, M R, Smith, S G

“…The prognosis for tracheobronchial tumours remains poor. Most patients can be offered only palliation. When the main symptom is breathlessness or refractory…”
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Value of washings and brushings at fibreoptic bronchoscopy in the diagnosis of lung cancer by Mak, V H, Johnston, I D, Hetzel, M R, Grubb, C

“…A retrospective study was performed to evaluate the diagnostic yield for lung cancer from histological biopsy specimens and from washings and brushings for…”
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Comparison of normal and asthmatic circadian rhythms in peak expiratory flow rate by Hetzel, M R, Clark, T J

“…A computer technique (cosinor analysis) has been used to evaluate circadian rhythms in airway calibre in normals and asthmatics. Two hundred and twenty-one…”
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Interstitial laser photocoagulation of normal lung parenchyma in rats by FIELDING, D. I, BUONACCORSI, G, HANBY, A, HETZEL, M. R, BOWN, S. G

“…Management of peripheral lung tumours may be risky in patients with poor lung function or in the elderly. A new possibility is interstitial laser…”
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Brittle asthma: fiend or phantom? by HETZEL, M R

“…[...]for type 1 brittle asthma they require a monitoring period of at least 150 days during which variation of >40% is observed for >50% of the time in spite…”
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Value of pulse oximetry in screening for long-term oxygen therapy requirement by Roberts, C M, Bugler, J R, Melchor, R, Hetzel, M R, Spiro, S G

“…Pulse oximetry, combined with spirometry, was evaluated as a method of selecting chronic obstructive pulmonary disease (COPD) out-patients requiring definitive…”
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The role of computed tomography (CT) in the investigation of unexplained haemoptysis by Millar, A B, Boothroyd, A E, Edwards, D, Hetzel, M R

“…Forty patients with a history of haemoptysis, normal chest radiographs apart from evidence of chronic airflow limitation, and normal fibreoptic bronchoscopy…”
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Debrisoquine metabolism and genetic predisposition to lung cancer by LAW, M. R, HETZEL, M. R, IDLE, J. R

“…It is usually the metabolites of environmental carcinogens that initiate a cancer, and if the metabolism were subject to genetically determined polymorphism,…”
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Commentary: yet more to see down the bronchial tree? by Hetzel, M. R.

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Fine-needle interstitial photodynamic therapy of the lung parenchyma: photosensitizer distribution and morphologic effects of treatment by Fielding, D I, Buonaccorsi, G A, MacRobert, A J, Hanby, A M, Hetzel, M R, Bown, S G

“…To look at the effect of interstitial photodynamic therapy (PDT) in normal lung parenchyma to assess its potential for treating localized, peripheral lung…”
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Metabolic oxidation phenotypes as markers for susceptibility to lung cancer by Ayesh, Riad, Idle, Jeffrey R, Ritchie, James C, Crothers, Michael J, Hetzel, Martin R

“…That bronchial carcinoma is not an inevitable consequence of cigarette smoking has stimulated the search for host factors that might influence the…”
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Interstitial laser photocoagulation and interstitial photodynamic therapy of normal lung parenchyma in the pig by Fielding, D I, Buonaccorsi, G, Cowley, G, Johnston, A M, Hughes, G, Hetzel, M R, Bown, S G

“…Interstitial laser photocoagulation (ILP) and interstitial photodynamic therapy (PDT) involve delivery of light to lesions in solid organs using thin fibres…”
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Experimental studies to assess the potential of photodynamic therapy for the treatment of bronchial carcinomas by Smith, S G, Bedwell, J, MacRobert, A J, Griffiths, M H, Bown, S G, Hetzel, M R

“…BACKGROUND--Photodynamic therapy (PDT) is a technique for producing localised tissue necrosis with light after prior administration of a photosensitising drug…”
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Elective resection of tumours of the trachea and main carina after endoscopic laser therapy by Shankar, S, George, P J, Hetzel, M R, Goldstraw, P

“…In our patients with tumour affecting the trachea or carina elective surgery was carried out after endoscopic laser treatment. Laser treatment was performed as…”
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The pulmonary clock by Hetzel, M R

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Changes in regional ventilation and perfusion of the lung after endoscopic laser treatment by George, P J, Clarke, G, Tolfree, S, Garrett, C P, Hetzel, M R

“…To determine whether endoscopic laser treatment improves both ventilation and perfusion in patients with advanced lung cancer, krypton-81m ventilation and…”
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Role of the neodymium YAG laser in the management of tracheal tumours by George, P J, Garrett, C P, Hetzel, M R

“…Twenty one patients with tracheal tumours (10 primary and 11 secondary) have been treated with the neodymium YAG laser under general anaesthesia. Fourteen of…”
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Maximal expiratory flow-volume curves in Londoners aged 60 years and over by Fowler, R W, Pluck, R A, Hetzel, M R

“…To obtain more accurate information about respiratory function in the elderly, we carried out spirometry and constructed maximum expiratory flow-volume curves…”
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