Search Results - "Hetz, Claudio A"
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ER stress signaling and the BCL-2 family of proteins: from adaptation to irreversible cellular damage
Published in Antioxidants & redox signaling (01-12-2007)“…Programmed cell death is essential for the development and maintenance of cellular homeostasis, and its deregulation results in a variety of pathologic…”
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Beyond apoptosis: nonapoptotic cell death in physiology and disease
Published in Biochemistry and cell biology (01-10-2005)“…Apoptosis is a morphologically defined form of programmed cell death (PCD) that is mediated by the activation of members of the caspase family. Analysis of…”
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Stressing out the ER: a role of the unfolded protein response in prion-related disorders
Published in Current molecular medicine (01-02-2006)“…Transmissible Spongiform Encephalopathies are fatal and infectious neurodegenerative diseases characterized by extensive neuronal apoptosis and the…”
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Diminishing Apoptosis by Deletion of Bax or Overexpression of Bcl-2 Does Not Protect against Infectious Prion Toxicity In Vivo
Published in The Journal of neuroscience (21-11-2007)“…B-cell lymphoma protein 2 (Bcl-2) and Bcl-2-associated X protein (Bax), key antiapoptotic and proapoptotic proteins, respectively, have important roles in…”
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Thy-1 binds to integrin β3 on astrocytes and triggers formation of focal contact sites
Published in Current biology (10-07-2001)“…Background: Thy-1 is an abundant neuronal glycoprotein in mammals. Despite such prevalence, Thy-1 function remains largely obscure in the absence of a defined…”
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Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase
Published in Journal of cell science (01-12-2002)“…Engagement of the Fas receptor promotes apoptosis by activation of caspases. In addition, alterations in plasma membrane lipid orientation and intracellular…”
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Emerging roles of the unfolded protein response signaling in physiology and disease
Published in Current molecular medicine (01-02-2006)Get more information
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