Search Results - "Hetuin, Dominique"

Dormant tumor cells develop cross-resistance to apoptosis induced by CTLs or imatinib mesylate via methylation of suppressor of cytokine signaling 1 by SAUDEMONT, Aurore, HAMROUNI, Abdelbasset, MARCHETTI, Philippe, JIZHONG LIU, JOUY, Nathalie, HETUIN, Dominique, COLUCCI, Francesco, QUESNEL, Bruno

“…In the BCR/ABL DA1-3b mouse model of acute myelogenous leukemia, dormant tumor cells may persist in the host in a state of equilibrium with the CD8(+)…”
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Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-γ and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway by Liu, Jizhong, Hamrouni, Abdelbasset, Wolowiec, Darius, Coiteux, Valérie, Kuliczkowski, Kazimierz, Hetuin, Dominique, Saudemont, Aurore, Quesnel, Bruno

“…Multiple myeloma (MM) cells inhibit certain T-cell functions. We examined the expression of B7-H1 (PD-L1), a B7-related protein that inhibits T-cell responses,…”
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A structural explanation of the effects of dissociated glucocorticoids on glucocorticoid receptor transactivation by Dezitter, Xavier, Fagart, Jérôme, Taront, Solenne, Fay, Michel, Masselot, Bernadette, Hétuin, Dominique, Formstecher, Pierre, Rafestin-Oblin, Marie-Edith, Idziorek, Thierry

“…There is a therapeutic need for glucocorticoid receptor (GR) ligands that distinguish between the transrepression and transactivation activity of the GR, the…”
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Transduction of bone marrow cells by the AdZ.F(pK7) modified adenovirus demonstrates preferential gene transfer in myeloma cells by Gonzalez, R, Vereecque, R, Wickham, T J, Facon, T, Hetuin, D, Kovesdi, I, Bauters, F, Fenaux, P, Quesnel, B

“…Adenoviral vectors can efficiently infect myeloma cell lines, but transduction of fresh myeloma cells performed at low multiplicity of infections (MOIs) showed…”
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In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors by Berthon, Céline, Driss, Virginie, Liu, Jizhong, Kuranda, Klaudia, Leleu, Xavier, Jouy, Nathalie, Hetuin, Dominique, Quesnel, Bruno

“…B7-H1 (PD-L1) is a B7-related protein that inhibits T-cell responses. B7-H1 participates in the immunoescape of cancer cells and is also involved in the…”
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NK cells that are activated by CXCL10 can kill dormant tumor cells that resist CTL-mediated lysis and can express B7-H1 that stimulates T cells by Saudemont, Aurore, Jouy, Nathalie, Hetuin, Dominique, Quesnel, Bruno

“…Tumor dormancy is a phenomenon where small numbers of tumor cells persist in the host for months or years. We previously showed in the DA1-3b/C3H mouse model…”
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Abstract 1342: RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage by Nugues, Anne-Lucie, Bouafia, Hassiba, Hetuin, Dominique, Berthon, Celine, Loyens, Anne, Bertrand, Elisabeth, Jouy, Nathalie, Idziorek, Thierry, Quesnel, Bruno

“…Introduction. Impairment in cell death pathways represents a general characteristic of most cancer cells. The receptor-interacting protein kinase 3 (RIP3)…”
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Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway by Liu, Jizhong, Hamrouni, Abdelbasset, Wolowiec, Darius, Coiteux, Valérie, Kuliczkowski, Kazimierz, Hetuin, Dominique, Saudemont, Aurore, Quesnel, Bruno

“…Multiple myeloma (MM) cells inhibit certain T-cell functions. We examined the expression of B7-H1 (PD-L1), a B7-related protein that inhibits T-cell responses,…”
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Induction of leukemia-specific CD8+ cytotoxic t cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-[alpha] by Saudemont, Aurore, Corm, Selim, Wickham, Thomas, Hetuin, Dominique, Quesnel, Bruno

“…Acute myeloid leukemia (AML) cells can be differentiated into dendritic cells (DCs) using appropriate combinations of cytokines but generation of autologous…”
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Induction of leukemia-specific CD8 cytotoxic t cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-α by Saudemont, Aurore, Corm, Selim, Wickham, Thomas, Hetuin, Dominique, Quesnel, Bruno

“…Acute myeloid leukemia (AML) cells can be differentiated into dendritic cells (DCs) using appropriate combinations of cytokines but generation of autologous…”
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γ‐Ray irradiation induces B7.1 expression in myeloid leukaemic cells by Vereecque, Rodolphe, Buffenoir, Geraldine, Gonzalez, Ricardo, Cambier, Nathalie, Hetuin, Dominique, Bauters, Francis, Fenaux, Pierre, Quesnel, Bruno

“…Expression of B7 molecules provides co‐stimulatory signals to T lymphocytes, which prevent the induction of anergy. It has been previously reported that B7.1…”
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Mis-splicing yields circular RNA molecules by Cocquerelle, C, Mascrez, B, Hétuin, D, Bailleul, B

“…We previously identified novel human ets-1 transcripts in which the normal order of exons is inverted, and demonstrated that although the order of exons is…”
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Transfer of p16inka/CDKN2 gene in leukaemic cell lines inhibits cell proliferation by Quesnel, B, Preudhomme, C, Lepelley, P, Hetuin, D, Vanrumbeke, M, Bauters, F, Velu, T, Fenaux, P

“…The gene encoding for p16ink4a, a negative regulator of transition between G1 and S phase, is homozygously deleted in a large proportion of acute lymphoblastic…”
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